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Digitale Medien

Post-transfusion malaria in thalassaemia patients (1990)

Choudhury, N. J. ; Dubey, M. L. ; Jolly, J. G. ; [weitere]

Springer

Annals of hematology 61 (1990), S. 314-316

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Details

ISSN: 1432-0584

Schlagwort(e): Transfusion malaria ; Thalassaemia ; Antigen detection

Quelle: Springer Online Journal Archives 1860-2000

Thema: Medizin

Notizen: Summary A total of 125 β-thalassaemia patients receiving repeated blood transfusions were screened by Giemsa stain, Acridine-orange stain and antigen detection for evidence of malaria infection on each visit. A total of 8 (6.4%) of the patients developed post-transfusion malaria (PMT) as confirmed by tracing the infected blood donors. A high incidence of PTM in thalassaemia patients appears to be due to the use of fresh blood and the high frequency of blood transfusions required by these patients. Antigen detection using monoclonal antibody was found to be more sensitive for diagnosis of PTM and for screening suspected donors than the conventional blood smear examination methods and is therefore recommended for routine blood donor screening to rule out malaria infection.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF01732885

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