ISSN:
1574-6968
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Biology
Notes:
Abstract Streptomyces griseus genomic DNA codes for two different streptomycin phosphotransferases. Both genes confer streptomycin resistance to their host. A cloned DNA fragment containing one of the two resistance determinants overlaps with another cloned segment of S. griseus genomic DNA, complementing 1 out of 3 classes of streptomycin-idiotrophic mutants. This demonstrates physical linkage of resistance and biosynthetic genes involved in streptomycin biogenesis in the genome of S. griseus.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1111/j.1574-6968.1985.tb01002.x
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