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  • Electronic Resource  (2)
  • 1990-1994  (1)
  • 1980-1984  (1)
  • 1993  (1)
  • 1981  (1)
  • Alprazolam  (1)
  • Flow symmetry  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Psychopharmacology 75 (1981), S. 258-261 
    ISSN: 1432-2072
    Keywords: Sleep ; Diazepam ; Alprazolam
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract One group of eight normal young males was administered three doses of alprazolam (0.25, 0.5 and 1.0 mg) and placebo, while a second group of eight normal young males was given three doses of diazepam (2, 5, and 10 mg) and placebo in the same design. All subjects slept in the sleep laboratory for 10 nights, 2 consecutive nights each week for 5 consecutive weeks. The first 2 nights served as adaptation. During the next 4 weeks subjects received a random dose of alprazolam (or placebo) or a random dose of diazepam (or placebo) each week. Similar dose-related benzodiazepine effects were found on sleep with both medications. Alprazolam reduced percent stage 4 and REM sleep and increased stage 2 sleep and latency to REM. Diazepam decreased percent stage 1 and increased percent stage 2 sleep. No drug by dose interactions were found. It was concluded that, while both drugs had similar effects on sleep, alprazolam showed significant effects on REM sleep parameters and might be evaluated for possible antidepressant effect.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Mathematical methods of operations research 38 (1993), S. 261-267 
    ISSN: 1432-5217
    Keywords: Flow symmetry ; algebraic flows ; directed graphs
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics , Economics
    Notes: Abstract Analgebraic flow for a digraphD=(V, A) is a generalization of acirculation forD in which the operation of addition is replaced by a binary operation defined over a commutative semigroup. A substantial literature exists in which flow-theory has been studied in this more general setting. For example, Hamacher has generalized the classical max-flow min-cut theorem to algebraic flows. In this paper, we show thatx is an algebraic flow if and only if for each pair of distinct verticess andt, the value of a maximum (s, t) algebraic flow with capacitiesx is equal to the value of a maximum (t, s) algebraic flow with capacitiesx. This characterization, which we callflow-symmetry, is a common generalization of two previous flow-symmetric results that have appeared in the literature. First, Lovász, by proving a conjecture of Kotzig, showed that flow-symmetry holds for the usual semigroup operation of addition of non-negative reals. That is, a vectorx≥0 defined on the arc setA is a circulation forD if and only if for each pair of distinct verticess andt the value of a maximum (s, t) flow inD with capacitiesx equals the value of a maximum (t, s) flow inD with capacitiesx. Second, in a previous paper, we showed that the analogous result holds for the semigroup in which the summation operator is replaced by the maximization operator. That is,x is amax-balanced flow if and only if for each pair of distinct verticess andt, the value of a maximum bottleneck (s, t) path inD with capacitiesx equals the value of a maximum bottleneck (t, s) path inD with capacitiesx. In this paper, we show that these results are each special cases of our characterization of an algebraic flow.
    Type of Medium: Electronic Resource
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