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  • Electronic Resource  (2)
  • 2000-2004  (1)
  • 1990-1994  (1)
  • 2000  (1)
  • 1991  (1)
  • Hydrochloric acid and chloride media  (1)
  • Key words: Ozone—Pulmonary inflammation—Ebselen—Peroxynitrite.  (1)
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  • Electronic Resource  (2)
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  • 2000-2004  (1)
  • 1990-1994  (1)
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  • 2000  (1)
  • 1991  (1)
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  • 1
    Electronic Resource
    Electronic Resource
    Ebselen Decreases Ozone-Induced Pulmonary Inflammation in Rats (2000)
    Springer
    Lung 178 (2000), S. 225-234 
    Details
    ISSN: 1432-1750
    Keywords: Key words: Ozone—Pulmonary inflammation—Ebselen—Peroxynitrite.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. We studied the effects of ebselen on rat lung inflammatory responses against ozone exposure. Rats were treated with ebselen every 12 h from 1 h before a single 4-h exposure to 2 ppm ozone. Treatment with ebselen (10 mg/kg) significantly decreased pulmonary inflammation as indicated by the albumin concentration and the number of neutrophils in the bronchoalveolar lavage fluid 18 h after the ozone exposure. Although treatment with ebselen did not alter the macrophage expression of inducible nitric oxide synthase after the ozone exposure, it did markedly inhibit the nitration reaction of tyrosine residues, suggesting that ebselen scavenges peroxynitrite during ozone-induced pulmonary inflammation. Treatment with ebselen also enhanced the pulmonary expression of both copper, zinc, and manganous superoxide dismutases at the same time point. These enzymes may also contribute to a decrease in the formation of peroxynitrite by lowering the concentration of superoxide. Thus, ebselen represents a useful compound for protecting against certain acute lung injuries by modulating the oxidant-related inflammatory process.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004080000026
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Chromatography of inorganic ions on diethyl-(2-hydroxy-propyl)aminoethyl cellulose layers in hydrochloric acid and in HCl-ammonium chloride media (1991)
    Springer
    Chromatographia 31 (1991), S. 60-62 
    Details
    ISSN: 1612-1112
    Keywords: Thin-layer chromatography ; Diethyl-(2-hydroxy-propyl)aminoethyl (QAE)-cellulose ; Hydrochloric acid and chloride media ; Inorganic ions ; Re(VII)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Summary Thin-layer chromatographic behavior of 49 inorganic ions has been systematically studied on diethyl-(2-hydroxy-propyl)aminoethyl (QAE)-cellulose, a strongly basic anion exchanger, in aqueous hydrochloric acid and in acid-ammonium chloride media (0.01 to 1.0 mol dm−3). Aspects of the adsorption behavior of the ions on the cellulose are compared with those on other anion exchangers in the same eluent system. Feasibilities of separation of multicomponent mixtures are proposed on QAE-cellulose in both media. In particular, the selective separation of Re(VII) from many other ions can be accomplished on these systems.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02290497
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    Paper (German National Licenses)
    Fulltext
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