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  • 1
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 72 (1992), S. 1660-1660 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 71 (1992), S. 4515-4522 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Palladium oxide thin films are studied by ellipsometry, optical transmission, and Raman scattering. The PdO films are made by completely oxidizing Pd films sputtered onto fused silica substrates, and their optical constants determined using a combination of ellipsometry and transmission measurements. Oxidation kinetics experiments are performed on thick Pd substrates at temperatures of 300–500 °C. The optical properties of the films show a thickness dependence suggesting an increased absorption at the PdO-Pd interface. Ellipsometry on oriented single crystals of PdO yields the anisotropic optical constants at 632.8 nm. These results are combined with an effective medium theory to show that the oxidized films have a void density of 20–25%. Raman scattering is demonstrated to be a very sensitive probe for detecting the presence of PdO on Pd. An oxide only a few A(ring) thick is readily detectable, despite the absence of any surface enhanced Raman effect.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 70 (1997), S. 520-522 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: A novel method for determining magnetic anisotropies from hysteresis loops is presented. While sweeping the loop, a magnetic field is applied perpendicularly to the sweep-field axis. This causes the magnetization to rotate reversibly in a wide field range and still reach saturation at finite fields. An example is given whereby surface and volume anisotropies are determined from magneto-optical Kerr effect loops in Co films grown on stepped Cu(001). © 1997 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1439-0523
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Several genetic maps for sugar beet (Beta vulgaris L.), from different German research groups, have been published and it is now possible to consider combining them with the aid of the common markers. The computer program JOINMAP (versions 1.3 and 2.0) was used for pair-wise combination of three populations. Several problems arose: the genetic background of the populations, different population structures (F2 versus F1× F1), different number of polymorphic loci for common probes in the populations to be combined, different estimates of the recombination rates between the same markers and differences between the JoinMap versions. The maps from two F2 populations could be integrated into a single map, but it was more appropriate to construct separate maps for the F2 populations and the F1× F1 population using common markers as reference points only.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1520-4995
    Source: ACS Legacy Archives
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1439-0523
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: The linkage relationship between eighteen isozyme loci and the morphological markers hypocotyl colour (R-r), monogerm character (M-m), pollen fertility (X) and stem fasciation (Verb.) are tested. Three linkage groups could be set up, involving all morphological marker loci and eight of the isozyme loci. Est-2, R-r, Fdp-2, Got2 and Icd-1 belong to linkage group I, linkage group II includes the loci Fas-fas M-m, Est-3 and Aco-1, linkage group III contains the loci X, Mdh-1 and Est-5.When analysing the inheritance of isozymes and RFLPs, deviations are usually found in some lines from the expected frequencies of a 3 : 1 or 1 : 2 : 1 segregation at single marker loci. In many cases these data can still be used for the estimation of recombination values with linked loci under the control of selection. Procedures to estimate linkage in such cases are given and applied to experimental data in Beta vulgaris.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    [S.l.] : International Union of Crystallography (IUCr)
    Acta crystallographica 48 (1992), S. 626-639 
    ISSN: 1600-5724
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Notes: It is shown in this paper that the reflectivity of X-rays at smooth and fiat surfaces gives the dispersive correction f′(E) to the atomic form factor with an accuracy comparable to that obtained by X-ray interferometry. A detailed set of values of f′(E) in the energy range 7–27 keV is given for Ni, Cu, CuO, Ta, LiTaO3, Pt and Au, together with the corresponding linear absorption coefficients μ/ρ. Whenever comparison is possible the values of f′(E) agree very well with those obtained by interferometry or by Kramers–Kronig transformation. Data calculated according to Cromer & Liberman [J. Chem. Phys. (1970). 53, 1891–1898] agree well with our data far from absorption edges. At the edges there are substantial differences because the calculations do not take into account the structure of the edges, their chemical shift in compounds and the EXAFS structure above the edges. Below absorption edges the values of f′(E) for metals and their oxides are equal, provided the chemical shift in the position of the edges is taken care of. This feature is interesting in anomalous scattering experiments, where the variation off' with energy is used to vary the scattering contrast of a given atomic species. Once f′(E) is known, X-ray reflectivity measurements can be used to determine the density and the thickness of layers on fiat substrates. In addition, the roughness of the air-layer and layer-substrate interfaces have been determined with high precision in the metals and oxides mentioned above.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1432-1440
    Keywords: Insulin action ; Insulin pharmacokinetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary To compare the pharmacokinetics of two different concentrations, containing either 40 or 100 IU/ml of short-acting human insulin (Velasulin HM), intermediate-acting human insulin (Insulatard HM), or an insulin mixture (25% short-acting insulin, 75% intermediate-acting insulin; Mixtard HM), three randomized, single-blind, crossover trials were performed using the euglycemic clamp technique. Eighteen healthy volunteers received insulin of either formulation subcutaneously in each of the studies (15 IU Velasulin, 20 IU Insulatard, or Mixtard). The blood glucose levels were maintained constant by glucose infusions. In the trial using Velasulin, the two different insulin concentrations were equivalent regarding the total absorption [area under the curve (AUC) of serum insulin: 126 ± 28 and 123 ± 35 mU/1 x 12 h for U40 and U100 (x ± SD)], but not in regard to the rate of absorption (t max 1.3 ± 0.4 and 2.4 ± 1.0 h for U40 and U100). In the case of Insulatard, total absorption was not equivalent (AUC 153 ± 35 and 128 ± 37 ml/l x 24 h for U40 and U100), but the rate of absorption was equivalent (t max 4.8 ± 2.9 and 5.3 ± 4.6 h). In the Mixtard series, total absorption was equivalent (AUC 142 ± 32 and 128±22 mU/1 x 24 h), but the rate of absorption was not (t max 2.2 ± 0.9 and 3.2 ± 4.2 h for U40 and U100). The glucose requirement was not equivalent in each of the three series. It was higher for the U-100 formulation in the Velasulin trial (2363±578 ml/12 h for U40 and 2601 ± 820 mi/ 12h for U100) and lower in the Insulatard trial (2203 ± 1271 ml/24 h for U40 and 1864 ± 864 ml/ 24h for U100) and the Mixtard trial (2559 ± 914 ml/24h for U40 and 2067 ± 896 ml/24 h for U100). When switching insulin from U40 to U100 formulations, more frequent blood glucose monitoring in the early phase following the insulin injection is recommended.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1432-2013
    Keywords: Key words Human nasal epithelium ; Nicotine ; Nicotinic receptor ; Epithelial Na+ channel ; Intracellular Ca2+
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  We investigated the effects of nicotine and its derivate nicotine di-d-tartrate on primary cultured human nasal epithelial cells. Both substances evoked an in-crease in the intracellular free calcium concentration. In the presence of extracellular Ca2+ the cytosolic Ca2+ ([Ca2+]i) increase was long lasting, whereas in the absence of external Ca2+ there was a transient increase of [Ca2+]i indicating that nicotine has an influence on Ca2+ conductances across the membranes and on intracellular Ca2+ stores. Both effects could be blocked by the nicotinic receptor antagonist methyllycaconitine (MLA). Apical or basolateral application of nicotine during transepithelial transport measurements with confluent monolayers of cultured human nasal cells resulted in a significant, reversible decrease of amiloride-sensitive sodium absorption with an apparent half-maximal blocker concentration of about 950 μM. To exclude the possibility that remnant neuronal components were responsible for the observed effects we used tetrodotoxin and verapamil to block putative neuronal channels and 4-(4-diethyla- mino)styryl-N-methylpyridinium iodide (4-di-2-Asp) to stain neuronal tissue. Both experimental approaches demonstrated that there were no neuronal-mediated effects. These results indicate the direct effects of nicotine on human nasal epithelium, giving the first evidence of the existence of nicotinic receptors in non-excitable cells.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 43 (1992), S. 209-210 
    ISSN: 1432-1041
    Keywords: Moxonidine ; Hydrochlorothiazide ; pharmacokinetics ; drug interaction ; steady-state ; healthy volunteers ; adverse effects
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Type of Medium: Electronic Resource
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