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  • Electronic Resource  (2)
  • 1995-1999  (2)
  • 1999  (1)
  • 1996  (1)
  • Key words:Antilactoferrin antibody – Antimyeloperoxidase antibody – Autoantibody – Polyclonal B-cell activation  (1)
  • Polymyositis  (1)
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  • Electronic Resource  (2)
Years
  • 1995-1999  (2)
Year
  • 1999  (1)
  • 1996  (1)
Keywords
  • 1
    Electronic Resource
    Electronic Resource
    The main HTLV-I-harboring cells in the muscles of viral carriers with polymyositis are not macrophages but CD4+ lymphocytes (1996)
    Springer
    Acta neuropathologica 92 (1996), S. 358-361 
    Details
    ISSN: 1432-0533
    Keywords: Key words In situ polymerase chain reaction ; Immunohistochemistry ; Human T cell lymphotropic ; virus type I ; Proviral DNA ; Polymyositis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We have analyzed muscle biopsy specimens from polymyositis patients who are also positive for human T cell lymphotropic virus type I (HTLV-I) using both immunohistochemistry for surface antigens of lymphocytes and macrophages and in situ polymerase chain reaction for HTLV-I proviral DNA on the same sections. We found HTLV-I in CD4+ cells but not in macrophages. This finding suggests that most of the HTLV-I-containing CD4+ cells are not macrophages but lymphocytes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004010050530
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Antineutrophil Cytoplasmic Antibody in Patients with Primary Sjo¨gren’s Syndrome (1999)
    Springer
    Clinical rheumatology 18 (1999), S. 268-271 
    Details
    ISSN: 1434-9949
    Keywords: Key words:Antilactoferrin antibody – Antimyeloperoxidase antibody – Autoantibody – Polyclonal B-cell activation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract: The incidence, specificity and clinical significance of positivity for serum antineutrophil cytoplasmic antibody (ANCA) was investigated in 60 patients with primary Sjögren’s syndrome (SjS). The indirect immunofluorescence (IIF) technique and an enzyme-linked immunosorbent assay (ELISA) were used to measure ANCA. Purified myeloperoxidase (MPO), lactoferrin (LF), cathepsin-G (CTG) and elastase (HLE) served as ANCA antigens for the ELISA. Ten (16.7%) of the 60 SjS patients showed positivity by IIF for perinuclear, but not cytoplasmic, ANCA. Four of the 60 sera were shown to be positive for LF, four for MPO, 0 for CTG and 0 for HLE by ELISA. There was no correlation between ANCA positivity and clinical features. ANCA in patients with SjS might be an epiphenomenon of polyclonal B-cell activation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s100670050100
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
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