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  • Electronic Resource  (20)
  • 2005-2009  (2)
  • 2000-2004  (9)
  • 1955-1959  (9)
  • 1
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 71 (2000), S. 836-838 
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: For the International Fusion Materials Irradiation Facility (IFMIF) scenario, a 140 mA deuterium beam in continuous wave (cw) mode with an atomic yield of above 85% is required. The normalized root-mean-square emittance should be less than 0.2 π mm mrad at the entrance of a RFQ. As part of a conceptual design for IFMIF, a new ion source has been developed and is tested at the Institut für Angewandte Physik in Frankfurt. The ion source is of the volume type with a tungsten cathode driving the discharge. Both cw and pulsed mode are possible and were studied. First experiments were carried out with deuterium. 80 mA deuterons with a D+ fraction of above 90% were extracted [A. Maser et al., Rev. Sci. Instrum. 67, 1054 (1996)]. In order to avoid neutron generation by the d–d reaction, hydrogen was used instead of deuterium later on. As far as the ion source and plasma production processes are concerned, the use of hydrogen instead of deuterium is equivalent because of their similar atomic shells. Recently, a 200 mA proton beam at 55 kV was extracted in cw mode (according to Child–Langmuir, 200 mA H+ corresponds to 140 mA D+) with a H+ fraction of 93%. This article will give a detailed description of the ion source and the essential experimental results. Especially, the influence of important physical parameters (such as discharge current and strength of the filter field) on the H+ fraction was studied. By using different kinds of auxiliary gases, the influence on the H+ fraction and the noise level were investigated, too. © 2000 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Analytical chemistry 31 (1959), S. 579-581 
    ISSN: 1520-6882
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 73 (2002), S. 1027-1029 
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: For the International Fusion Materials Irradiation Facility project (IFMIF) the Institut für Angewandte Physik at the University of Frankfurt is concerned with developing a high current proton/deuteron ion source. The 1999 "Frankfurt 200 mA Proton Source" is a volume type belonging to the high-efficient ion-sources family. This type of ion source has proven its capability to produce high-current ion beams of a single mass-to-charge ratio at very low-beam emittances. The arc discharge ion source delivers a 200 mA full beam (93% protons) at 55 keV with very high-beam intensities (outlet aperture 8 mm diam). Thus, the beam requirements for the IFMIF project are fulfilled. After having done the basic plasma investigation with a 127° cylinder spectrometer, the quality of the ion beam was a point of interest. Therefore, the beam emittance was measured with a conventional slit-grid measurement device. The goal was to measure the beam emittance at high-beam currents. The article will give a detailed description of the measurement of a 56 mA beam at 26 keV with 85% protons. Theoretical considerations of the emittance value, given by ion temperature and aberrations of the extraction system, allows an estimation of the emittance of a 170 mA at 55 keV proton beam. In a second step, an estimation of a postaccelerated 140 mA at 100 keV deuteron beam was completed. © 2002 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Berlin, Germany : Blackwell Verlag GmbH
    Anatomia, histologia, embryologia 34 (2005), S. 0 
    ISSN: 1439-0264
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Bone marrow derived stromal cells are of mesenchymal origin and precursor cells for skeletal tissue components such as chondroblasts and osteoblasts. Furthermore, under experimental conditions, a differentiation potency into myogenic and neuronal cells could be demonstrated. Because of their multipotency these cells represent a population of non-haematogen stem cells that can be regarded as an alternative to human embryonic stem cells for future autologous cell replacement therapies. For a closer look at the differentiation capacity of these cells, rat and human bone marrow stromal cells were isolated from the femur bone and kept in the cell culture applying different cultivation protocols. In a cultivation medium with a serum content of 20%, the majority of these cells express a variety of neuronal markers such as ß-III Tubulin and NeuN as well as the astrocyte marker GFAP, while a minority of about 20% express the marker for neural precursor cells nestin. Cultivation in a chemically defined serum free medium results in the differentiation of a markedly higher percentage of nestin positive neural precursor-like cells. Using bFGF in combination with B27 these cells can be forced to form three dimensionally organized spheres. In order to elucidate a possible therapeutical potency of the bone marrow derived cells the synthesis of neurotrophic factors such as BDNF and NGF were analysed using the ELISA technique. Furthermore, they can be infected using a third generation adenoviral vector with high efficiency and show migratory activity in vitro. After injection of bone marrow derived mesenchymal stem cells into the lateral ventricle of adult rats they adhere to the ependymocytes and pass the ependymal barrier in order to settle in the subventricular space.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Berlin, Germany : Blackwell Verlag GmbH
    Anatomia, histologia, embryologia 34 (2005), S. 0 
    ISSN: 1439-0264
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Brain injury remains a significant and potentially devastating outcome of cardiopulmonary bypass (CPB) under circulatory arrest. These outcomes caused by a microvasculature embolization are associated with increased mortality, longer hospital stays and increased use of intermediate or long term care facilities. The administration of heparin in heart surgery during deep hypothermic cardiopulmonary bypass is the basic prophylactic strategy for reducing or even preventing, microvasculature embolization. Unfortunately, an incidence of neuropsychological impairments (NPI) is found in as many as 25 % of the survivors. As it is suspected that these impairments are correlated with morphological alterations, in our study we use the GP IIb-IIIa receptor blocker Eptifibatide for the inhibition of platelet aggregation, in order to look for a reduction of tissue damage compared to the standard treatment. Two groups of 11 piglets (mean body weight of 15±5 kg) underwent 10-minute normothermic bypass, 40-minute cooling on cardiopulmonary bypass, 60-minutes deep hypothermic circulatory arrest (DHCA) at 15°C, and 40-minute rewarming to 37°C. Group 1 was treated only with unfractionated heparin (UFH), whereas Group 2 was medicated with Eptifibatide, in addition to the UFH-treatment group 1. After rewarming, all animals underwent bilateral carotid perfusion with 4% paraformaldehyde. Histological investigations of semi thin sections reveal a marked decrease of hippocampal alterations by using the GP IIb-IIIa receptor blocker in addition to standard UFH treatment. We detect a reduction of degenerative areas in perivascular (vessels with 10–30 μm in diameter) tissue. These semi-quantitative data are confirmed by ultrastructural findings.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Copenhagen : International Union of Crystallography (IUCr)
    Applied crystallography online 33 (2000), S. 1162-1174 
    ISSN: 1600-5767
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Geosciences , Physics
    Notes: The instrumental transparency functions of five commercially available texture goniometers were measured experimentally with six monocrystalline samples cut in different orientations from a large highly perfect silicon crystal with a rocking curve of less than 0.01°. Transparency functions were measured in steps of 0.02 to 0.2° in the pole-figure angles α, β. The window size Δα depends on the Bragg angle θ in the form 1/sinθ; the window size Δω is constant for each goniometer. The dominant instrumental parameter determining the long axis Δα of the pole-figure window is the axial width of the detector entrance slit. This parameter is smallest for area detectors (smaller by more than an order of magnitude compared with conventional scintillation detectors as well as one-dimensional position-sensitive detectors). The main features of the pole-figure window and their dependence on the instrumental parameters can be deduced fairly well from a simple geometrical model. The particular shapes of the transparency functions of the studied goniometers are markedly different. Particularly, they are not very well represented by Gauss functions. The two-dimensional transparency function can be fairly well characterized by its α and β profiles. The normalized profiles are virtually independent of the goniometer angles 2θ and α. The increasing size of the pole-figure window with decreasing θ puts a lower limit on the Bragg angle below which pole-figure measurement ceases to be meaningful.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    International journal of legal medicine 44 (1955), S. 262-272 
    ISSN: 1437-1596
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Law
    Notes: Zusammenfassung 1. Zur Beurteilung interstitieller lymphocytärer Entzündungen der Säuglings- und Kleinkindlunge wurden 100 mit Ausnahme spezifischer Prozesse nicht ausgewählte Lungen vom Ende des 1. bis einschließlich des 6. Lebensmonates so untersucht, daß ein Querschnitt durch jeden Lungenlappen beurteilt werden konnte, die lymphocytäre Infiltration des Zwischengewebes in Grad I, II und III eingeteilt und diese Gradeinteilung zu Bronchitis, Peribronchitis und Bronchopneumonie in Beziehung gesetzt. Dabei ergab sich: a) In 51 Lungen waren keine bemerkenswerten, in 38 Lungen geringfügige, topographisch uncharakteristische Veränderungen des Zwischengewebes festzustellen; b) in 11 Lungen bestand eine starke und ausgedehnte lymphocytäre Infiltration als einziges Zeichen einer vorausgegangenen Erkrankung. 2. Die unter 1. b) beschriebenen Lungenveränderungen sind bei plötzlichen Todesfällen im Säuglings- und frühen Kindesalter bei der Beurteilung der Todesursache zu berücksichtigen. 3. Eine bisher weniger beachtete pulmonale Todesursache („interstitielle lymphocytäre Pneumonie mit Ödem”) wird auf Grund von 7 gerichtsmedizinischen Beobachtungen beschrieben. 4. Es wird über 9 plötzliche Todesfälle infolge interstitieller plasmacellulärer Pneumonie unter Berücksichtigung der bei einzelnen Formen bestehenden diagnostischen Schwierigkeiten berichtet.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    International journal of legal medicine 44 (1955), S. 538-549 
    ISSN: 1437-1596
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Law
    Notes: Zusammenfassung 1. Um die Möglichkeiten einer vaginalcytologischen Diagnose des provozierten Abortes unter gerichtsmedizinischen Gesichtspunkten zu prüfen, wurden Ausstriche aus dem Scheidengewölbe von 300 Frauen (darunter 100 Frauen nach klinisch festgestelltem Abort) qualitativcytologisch wie quantitativ nach der Zellzahl untersucht; es ergab sich: a) Der Scheidenzustand ist während Cyclus, Schwangerschaft, vor und nach Abort so unterschiedlich, daß eine cytologische Diagnose möglich ist. b) Der drohende oder, nach Eintritt, nicht-fieberhafte anamnestisch nicht-provozierte Abort ist gekennzeichnet durch die zuerst ansteigende, unmittelbar nach Abort hohe Zahl charakteristischer eosinophiler Zellen. c) Der fieberhafte Abort ist gekennzeichnet durch hohe Zahl basophiler Zellen und Schleim, eine niedrige Zahl eosinophiler Zellen, die erst später, nach 8 Tagen, wieder beträchtlich zunehmen. 2. Die experimentellen Beobachtungen bei künstlicher Unterbrechung der Trächtigkeit der Ratte stimmen vaginalcytologisch mit den Beobachtungen bei fieberhaftem Abort grundsätzlich überein. 3. Die Diagnose eines provozierten Abortes kann vaginalcytologisch begründet sein, unter gerichtsmedizinischen Bedingungen allein, als einziger Beweis, nicht ausreichen, aber ausschlaggebend sein, wenn sie sich in weitere Beweise einfügt.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    International journal of legal medicine 45 (1956), S. 17-20 
    ISSN: 1437-1596
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Law
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    International journal of legal medicine 45 (1956), S. 510-515 
    ISSN: 1437-1596
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Law
    Notes: Zusammenfassung Die Gl. submaxillaris zeigte in 29 von 35 sicheren E 605-Vergiftungen einen je nach der Zeitdauer der Vergiftung wechselnden Zustand vorgeschrittener Mitochondriolyse, vacuolärer Cytolyse bis zu vollständigem Zellkollaps. In quantitativ-cytologischen Untersuchungen wurde durch Bestimmung der Mitochondrienzahl nach experimenteller E 605-Vergiftung die cytologisch beim Menschen beobachtete Mitochondriolyse bestätigt. Die beschriebenen Zellveränderungen können als charakteristisch angesehen werden. Bei der mikroskopischen Untersuchung von E 605-Vergiftungen sollte die Speicheldrüse mituntersucht werden.
    Type of Medium: Electronic Resource
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