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  • Digitale Medien  (2)
  • 2005-2009
  • 1990-1994  (2)
  • global ischemia  (1)
  • surgical indications  (1)
Materialart
  • Digitale Medien  (2)
Erscheinungszeitraum
  • 2005-2009
  • 1990-1994  (2)
Jahr
  • 1
    Digitale Medien
    Digitale Medien
    Springer
    Acta neurochirurgica 124 (1993), S. 71-78 
    ISSN: 0942-0940
    Schlagwort(e): Ischaemic cerebrovascular disease ; unruptured intraeranial aneurysm ; surgical indications ; results ; subarachnoid haemorrhage
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Out of 3435 patients with ischaemic cerebrovascular disease 2540 cases were investigated using cerebral angiography. In 127 of them (5%) aneurysms were found, but without clinical evidence of subarachnoid haemorrhage (SAH). 45 cases were operated upon and 82 were treated conservatively. Five of these 82 cases (6%) suffered from SAH 3 months to 10 years (mean interval 5,6 years) after the angiographic diagnosis. Four of these 5 patients with SAH died. Among the 45 surgical cases follow-up was uneventful in 29 (64%). The other 16 cases postoperatively showed neurological deterioration (36%), which was transient in 6 but with only minor improvement in 10. Of these 10 cases 2 died from cerebral infarction related to intra-operative temporary vascular occlusion respectively myocardial infarction. Thus surgical mortality was 4% and permanent morbidity 18%. Causes of postoperative neurological deterioration were partly related to general arteriosclerotic changes and special fragility of the ischaemic brain, and partly to operative technique (excessive brain retraction, damage to cortical veins, occlusion of major vessels or damage to perforators, temporary artery occlusion). Apparently in cases with ischaemic cerebrovascular diseases operative procedures, which in other cases as a rule are well tolerated, may produce harmful effects. Therefore, in these cases, the indication for operative treatment of so far silent aneurysms should be restricted to patients who are in good general condition with longer life expectancy as far as the vascular disease is concerned, and without major neurological deficit. Furthermore, the operative technique should be especially gentle and atraumatic.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Springer
    Basic research in cardiology 89 (1994), S. 250-259 
    ISSN: 1435-1803
    Schlagwort(e): Electrical pacing ; global ischemia ; reperfusion ; isolated nonworking heart ; calcium
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary The effects of electrical pacing during the early reperfusion following hypothermic global ischemia (60 min, at 25°C) was studied in the isolated working rat heart model. The hearts were divided into three groups. Hearts in Group I (n=8) were control without hypothermia, ischemia or pacing. Hearts in Group II (n=16) were paced with ventricular rate at 300 beats/min with 1 m Volt for 10 min during the Langendorff mode after an initial 5 min of reperfusion. Hearts in Group III (n=14) were not paced. The recovery of aortic flow (both absolute and percent) was significantly better in Group II than in Group III, but was significantly lower in both groups than in control. No significant differences were noted, however, in heart rate, aortic pressure or coronary flow between Group II and III. In contrast, the tissue concentration of adenosine triphosphate (ATP) in Groups II and III decreased significantly by the end of reperfusion relative to Group I, but no difference in ATP existed between Group II and III. Myocardial ATP concentrations did not correlate with percent recovery of aortic flow. The myocardial concentration of calcium in Groups II and III increased by the end of reperfusion as compared with Group I, but no difference in calcium existed between Group II and III. The myocardial concentration of calcium demonstrated a significant correlation with percent recovery of aortic flow (r=0.71, n=30,p〈0.005). Our results indicate that an electrical pacing during early reperfusion in the myocardium improves functional recovery of aortic flow.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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