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  • Electronic Resource  (2)
  • 1995-1999  (2)
  • Constipation  (1)
  • Engineering  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Diseases of the colon & rectum 38 (1995), S. 509-513 
    ISSN: 1530-0358
    Keywords: Colon ; Innervation ; Nerves ; Muscle ; Immunohistochemistry ; Constipation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract PURPOSE: This study was designed to investigate neural and muscular features of the colonic wall in patients with severe idiopathic constipation. METHODS: By using quantitative immunohistochemistry, resected specimens from 14 patients with idiopathic chronic constipation and 17 nonobstructed cancer controls were studied. RESULTS: Routine histology revealed no significant histologic abnormality throughout the colon apart from four cases of melanosis coli. Ratio of the thickness of circular to longitudinal muscle was significantly lower in the left colon in constipated subjects. The myenteric plexus appeared morphologically normal in all subjects. S-100 protein, which stains neuronal supporting tissues, demonstrated an increase in the proportion of neural tissue in the myenteric plexus. There was an increased number of PGP-9.5 immunoreactive nerve fibers in the muscularis propria in constipated patients, and this was significantly higher in the ascending and descending colon. CONCLUSION: Intractably constipated patients have alterations in the neural composition of the colonic myenteric plexus and innervation of the circular muscle.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 41 (1998), S. 1133-1151 
    ISSN: 0029-5981
    Keywords: flow control ; numerical solution of Navier-Stokes equation ; Karhunen-Loève Galerkin procedure ; Engineering ; Numerical Methods and Modeling
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: A new method of solving the Navier-Stokes equations efficiently by reducing their number of modes is proposed in the present paper. It is based on the Karhunen-Loève decomposition which is a technique of obtaining empirical eigenfunctions from the experimental or numerical data of a system. Employing these empirical eigenfunctions as basis functions of a Galerkin procedure, one can a priori limit the function space considered to the smallest linear subspace that is sufficient to describe the observed phenomena, and consequently reduce the Navier-Stokes equation defined on a complicated geometry to a set of ordinary differential equations with a minimum degree of freedom. The present algorithm is well suited for the problems of flow control or optimization, where one has to compute the flow field repeatedly using the Navier-Stokes equation but one can also estimate the approximate solution space of the flow field based on the range of control variables. The low-dimensional dynamic model of viscous fluid flow derived by the present method is shown to produce accurate flow fields at a drastically reduced computational cost when compared with the finite difference solution of the Navier-Stokes equation. © 1998 John Wiley & Sons, Ltd.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
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