ISSN:
1432-1076
Keywords:
Key words Galactoasemia
;
Portosystemic shunt
;
Total bile acids
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract To determine whether plasma levels of total bile acids may provide a useful index for hypergalactosaemia due to porto-systemic shunts, these levels were determined in hypergalactosaemic neonates. Increased levels were found in all cases with portohepatic venous or portocaval shunts. The levels of both total bile acids and galactose were normalized when the shunts disappeared on the echograms. Both bile acids and galactose are almost completely absorbed by the liver via the first portal blood passage. Portosystemic shunts contribute to elevated levels of bile acids and galactose. Conclusion Increased plasma levels of total bile acids serve as a diagnostic clue to the presence of porto systemic shunts in neonates with hypergalactosaemia.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/s004310050697
Permalink
