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  • 1
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Macromolecules 24 (1991), S. 3136-3141 
    ISSN: 1520-5835
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    FEMS microbiology letters 82 (1991), S. 0 
    ISSN: 1574-6968
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Abstract: Cyclitol derivatives have been synthesized and screened for growth inhibitory effect upon prokaryotic and eukaryotic organisms. One derivative, (2S, 3R, 5R)-3-azido-2-benzoyloxy-5-hydroxycyclohexanone, was studied in detail: it has no effect upon bacteria, but it is inhibitory to Neurospora crassa. In Neurospora crassa it increased the amount of myo-inositol-1-phosphate synthase and inhibited the activity of myo-inositol-monophosphatase. The enhanced synthesis of myo-inositol-1-phosphate synthase was the consequence of lowering the intracellular inositol concentration. Li+ treatment of Neurospora crassa has effects similar to those of P.I.-658.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Experimental brain research 26 (1976), S. 1-17 
    ISSN: 1432-1106
    Keywords: Medial geniculate body ; Neuronal geometry ; Synaptic triplets ; Cat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Golgi and electron microscopic analysis of the known cellular layers in concentric shells of the ventro-lateral portion of the medial geniculate body revealed a flat grid of high density neuropil filling the space between the geniculocortical relay cells, forming essentially a single cell layer in each lamina. The “skeleton” of this neuropil grid is made up by the interdigitating dendritic tufts of the geniculocortical relay cells, joined together by a rich system of desmosomoid adhesion plaques. The “holes” of the “skeleton” are filled in by the multilobed dendritic appendages of Golgi type II interneurons and the grape-like terminals of the inferior collicular specific afferents. Additional axon terminals of other sources — terminals of descending corticogenicular fibers, axons of the Golgi type II interneurons and terminals of the initial collaterals of the geniculocortical relay cells — contribute only to a very insignificant fraction of neuropil volume. The Golgi type II interneurons are oriented in perpendicular direction to the cell layers so that they may bridge with their dendrites several successive layers. Although the general expression “synaptic glomeruli” used in other relay nuclei for this type of specific synaptic arrangement is hardly applicable to this grid-like neuropil, the essential synaptic articulation pattern of all thalamic relay nuclei is well maintained. The specific inferior collicular afferents are presynaptic to both relay cell dendrites and to the multilobed dendritic appendages of Golgi type II cells, which in turn are presynaptic to the same dendritic regions of the relay cells receiving the bulk of the specific afferents.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Supportive care in cancer 2 (1994), S. 56-60 
    ISSN: 1433-7339
    Keywords: Bone marrow transplantation ; Team ; Support ; Burnout ; Psychosomatic ; Liaison service
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Both patients and staff in a bone marrow transplantation (BMT) unit have to cope with the effects of an aggressive treatment that helps many patients but also kills some. This has led to the regular involvement of support services in most American BMT units. This article describes the experience in 4 years of continuous psychosomatic liaison activity at the BMT unit at the University Hospital in Basel. The specific stressors a transplant team is subject to are described, such as high morbidity and mortality of patients and the close relationship between patients and staff members. Support for the transplant team cosists in the following activities: a psychosocial interview with each patient at the beginning of his or her hospital stay; weekly psychosocial round-ups with the whole team; regular participation in ward rounds; organization of workshops to prevent burnout. Although an empirical evaluation of this approach is lacking, the clinical evidence suggests that constant and reliable team support helps to stabilize the team, adding to its inner security. This ultimately improves patient care.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Pediatric surgery international 8 (1993), S. 262-263 
    ISSN: 1437-9813
    Keywords: Ileocaecal valve ; Atresia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A case of ileocaecal atresia is presented. This is an exceedingly rare cause of obstruction in the newborn. The embryology of the ileocaecal valve is described and related to the possible cause of the atresia.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1437-9813
    Keywords: Posterior sagittal pull-through ; Recto-urinary ; fistula ; Urethral stricture ; Neurogenic bladder
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The use of the sagittal surgical approach to the rectum and urinary fistula in male patients with anorectal agenesis is addressed. Iatrogenic damage to the urethra (1 in 60 cases) and pelvic (2 in 60 cases) occurred when the operator had difficulty identifying the rectum intraoperatively and where inappropriate midline dissection was done. The importance of an adequate preoperative contrast rectogram and the intraoperative identification of the rectum with the aid of a catheter is emphazied. Perirectal blunt dissection is discouraged, the need for deep lateral directed tissue retraction is avoided by applying direct traction onto the freed rectum, and a long and wide portion of rectal wall is left in the midline on the urethra and bladder neck. The anatomy of the autonomic pelvic plexus at risk in the normal and congenitally abnormal case is described.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Virchows Archiv 324 (1954), S. 707-748 
    ISSN: 1432-2307
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1436-5073
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Summary In the turbidimetric determination of traces of phosphoric acid, in accord with the Hegedüs and Dvorszky version, employing strychnine nitrate, excellent reproducibility is attained only when the MoO3 employed for the preparation of the reagent contains 0.2–0.5% WO3/MoO3. If less than 0.01% WO3/MoO3 is present, large deviations in the obtained values ensue.
    Notes: Zusammenfassung Mit der turbidimetrischen Strychninnitrat-Methode für Phosphorspurenbestimmung nach der Version von Hegedüs und Dvorszky kann man nur dann ausgezeichnete Reproduzierbarkeit erreichen, wenn das für die Reagenszubereitung verwendete MoO3 0,2–0,5% WO3/MoO3 enthält. Falls weniger als 0,01% WO3/ MoO3 anwesend sind, kommt es zu starken Meßwertschwankungen.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1432-0568
    Keywords: Glial fibrillary acidic protein ; Glia ; Turtle brain
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The distribution of glial fibrillary acidic protein (GFAP)-immunoreactivity is described in serial Vibratome sections of the turtle brain. The results are discussed in relation to our previous studies of rat and chicken brains. In the turtle brain, the distribution of GFAP-positive elements is rather evenly abundant as compared to that observed in the chicken and rat. The GFAP-positive structures are fibers of different length and orientation, but the stellate cells are not GFAP-positive. The basic systems is the radial ependymoglia, directed from the ventricles toward the outer surface of the brain. This system also contains some transverse and randomly oriented fibers. The cell bodies are not usually GFAP-positive. The large brain tracts could be recognized by their weak immunostaining, but gray matter nuclei could not be identified on the basis of immunostaining against GFAP. The layers of the optic tectum could be distinguished, as well as the gray and white matter of brain stem and spinal cord and the molecular and granular layers of the cerebellum. In the cerebellum, a fiber system resembling the Bergmann-fibers, a strong midline raphe and coarse transverse fibers could be observed. These latter fibers have no equivalent in other cerebella. Their perikarya proved also to be GFAP-positive, and seemed to be dividing in the adult turtle brain. We conclude that the appearance of GFAP-positive stellate cells had a great importance in the evolution of avian and mammalian brains strengthening the thicker brain walls and assisting in the formation of local differences of GFAP-immunoreactivity in different brain areas.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Experimental brain research 26 (1976), S. 19-37 
    ISSN: 1432-1106
    Keywords: Medial geniculate body ; Interneurons ; Cat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Three different types of interneurons can be separated in the Golgi picture, and many of their details can be identified under the electron microscope, in the medial geniculate body (MGB) of the cat: (1) typical short axon Golgi II. cells of the thalamic type, (2) somewhat larger Golgi type II cells with medium range axon, and (3) spidery neurogliform short axon cells. The most distinctive features of the two first types (1) and (2) are their irregular drumstick shape appendages, increasing in number as well as in length and irregularity of their stalks towards the periphery of the dendrites. These appendages form the vast majority of synaptic profiles in the aggregations of synaptic neuropil (glomeruli) of the nuclei, and they are both presynaptic and postsynaptic by the usual standards applied for the evaluation of the polarity of synapses. The characteristic beaded dendrites of the (3) neurogliform cell type can be recognised particularly easily in the electron microscope picture. They are both presynaptic and postsynaptic in structural polarity. All identified process profiles of interneurons contain flattened (F.-type) or pleomorphic synaptic vesicles. Membrane contacts, in which the interneurons appear to be presynaptic are either of the symmetric (Gray type II) or of an intermediate type. The membrane contacts of postsynaptic portions of the interneurons are usually of the asymmetric type (Gray type I) and the presynaptic profiles contain round (R-type) vesicles. The larger one have been shown already earlier to be derived from specific sensory (inferior collicular) afferents, while many of the smaller ones could be identified in the present study as being derived from cortico-geniculate descending pathways, arising from the auditory areas. Some of the synaptic contacts of the interneurons are apparently derived from other interneurons, the presynaptic profiles being often equivocal or more likely of axonal origin (all interneurons have clear axons in the Golgi picture). The occurrence of three distinct types of interneurons — probably all of inhibitory nature — the complexity in synaptic arrangement, and more particularly in the dendritic linkage of numerous synaptic sites does not favour such simple explanations as surround inhibition by forward or by backward inhibition, but suggests more sophisticated modes of impulse processing in the MGB.
    Type of Medium: Electronic Resource
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