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  • Electronic Resource  (3)
  • 1990-1994  (3)
  • Anal stricture  (1)
  • Anorectal myectomy  (1)
  • Extracellular matrix  (1)
Source
Material
  • Electronic Resource  (3)
Years
  • 1990-1994  (3)
Year
Keywords
  • 1
    Electronic Resource
    Electronic Resource
    Videoproctographic assessment after restorative proctocolectomy (1990)
    Springer
    Diseases of the colon & rectum 33 (1990), S. 566-572 
    Details
    ISSN: 1530-0358
    Keywords: Restorative proctocolectomy ; J-pouch ; W-pouch ; Anal stricture ; Proctography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Videoproctography was performed in 40 patients after restorative proctocolectomy to evaluate pouch emptying, anopouch angle, and pelvic floor movement in relationship to functional outcome. Results were compared between the two different pouch designs tested and a control group of 26 patients who had an intact rectum. There was no difference in emptying between the two pouch designs or compared with the control subjects. Emptying did not influence either the frequency of defecation or patient soiling rate. The presence of an anal stricture was associated with poor emptying in each case in the pouch group. Anorectal angle was no different between the different pouch designs or compared with the control group at rest, during pelvic floor contraction, or attempted defecation. A similar finding was obtained with anorectal angle position and movement during pelvic floor contraction and attempted defecation in both pouch design groups and when compared with normal rectum. This study shows that the only factor that is consistently associated with poor pouch emptying is the presence of an anal stricture.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02052208
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Long-term results of anorectal myectomy for chronic constipation (1990)
    Springer
    Diseases of the colon & rectum 33 (1990), S. 795-797 
    Details
    ISSN: 1530-0358
    Keywords: Constipation ; Anorectal myectomy ; Aganglionosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Anorectal myectomy has been shown to provide clinical benefit to patients with outlet obstruction. Long-term results of anorectal myectomy have been evaluated in 57 patients operated on between February 1984 and February 1988 with a median follow-up of 24 months. Overall improvement was recorded in only 31 percent of patients. Spontaneous evacuation without the need for laxatives was recorded in only 11 patients (19 percent), while 38 (67 percent) had no functional improvement. Results were independent of preoperative colonic transit or histologic evidence of aganglionosis. Anorectal myectomy identified aganglionosis in 23 percent of patients with chronic constipation, but there was minimal long-term benefit from the procedure.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02052329
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Immunoreactivity of the JK-132 monoclonal antibody directed against basement membrane collagen in normal and diabetic glomeruli (1994)
    Springer
    Virchows Archiv 424 (1994), S. 235-241 
    Details
    ISSN: 1432-2307
    Keywords: Diabetes mellitus ; Type IV collagen ; Glomerulus ; Extracellular matrix ; Monoclonal antibody
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The possible involvement of basement membrane-associated collagen (recognized by the monoclonal antibody JK-132) in the evolution of diabetic nephropathy was studied in kidney specimens from seven patients with noninsulin-dependent diabetes mellitus, and its distribution was compared with those of antibodies against α1 to α4 chains of type IV collagen. JK-132, a monoclonal antibody against basement membrane-associated collagen, reacted immunohistochemically exclusively with the mesangial matrix of the glomerular capillary. In contrast, antibodies to the α1 and α2 chains (IV) reacted strongly with mesangial matrix, and less strongly with the glomerular basement membrane (GBM). Antibodies to the α3 and α4 chains (IV) reacted mainly with GBM. In diabetes, JK-132 reacted most extensively with the expanded mesangial matrix, its staining intensity increasing with progression of the diabetic glomerulosclerosis. Antibodies to the α1 and α2 chains (IV) reacted prominently with the expanded mesangial matrix but less strongly with the GBM. Antibodies to the α3 and α4 chains reacted intensely with the thickened GBM. These results suggest that basement membrane-associated collagen differs from α1 to α4 chains of type IV collagen and that basement membrane-associated collagen is a good marker of mesangial expansion in diabetic nephropathy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00194606
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    Paper (German National Licenses)
    Fulltext
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