ISSN:
1420-9071
Keywords:
Gerbil
;
adrenal cortex
;
isocitric dehydrogenase
;
mitochondria
;
steroid
;
steroid hydroxylation
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary In gerbil adrenal cortex the activity of intramitochondrial NADP-linked isocitric dehydrogenase (IDH) is up to 10-fold greater than the NAD-linked IDH. The NADP-IDH, apparent Km 0.58 mM, Vmax 280 nmoles/min/mg mitochondrial protein, appears to be the major source of reducing equivalents to support adrenal mitochondrial steroid 11B- and 19-hydroxylation in this species.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01966160
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