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  • Electronic Resource  (4)
  • 1985-1989  (4)
  • Anguilla rostrata (Teleostei)  (1)
  • Barbiturates  (1)
  • CL 218,872  (1)
  • Clostridium acidiurici  (1)
  • surfactants
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  • Electronic Resource  (4)
Years
Year
Keywords
  • 1
    Electronic Resource
    Electronic Resource
    Sleep induction by an adrenal steroid in the rat (1987)
    Springer
    Psychopharmacology 93 (1987), S. 226-229 
    Details
    ISSN: 1432-2072
    Keywords: Benzodiazepines ; Barbiturates ; Steroids ; Chloride channel
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The ring A reduced metabolites of deoxycorticosterone and progesterone, 3alpha,5alpha-tetrahydrodeoxycorticosterone (THDOC) and 3alpha-hydroxy-5alpha-dihydroprogesterone (3alpha-OH-DHP) have been shown to be potent barbiturate-like ligands of the benzodiazepine receptor complex. The former has also been reported to have anxiolytic effects in mice and rats. In the present study, sleep recordings were obtained on rats given 5 and 10 mg/kg of these steroids alone and in combination with flurazepam. THDOC, but not 3alpha-OH-DHP, had potent dose-dependent sleep-inducing properties and increased nonREM sleep. Flurazepam had similar hypnotic effects and also reduced REM sleep. There were no significant interactions between THDOC and flurazepam, except in the case of REM latency, which tended to increase when the two compounds were given together. In summary, THDOC, a mineralocorticoid metabolite found in brain, has sedative properties and could conceivably play a role in stress responses.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00179939
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Accumulation and incorporation of 185W-tungsten into proteins of Clostridium acidiurici and Clostridium cylindrosporum (1987)
    Springer
    Archives of microbiology 147 (1987), S. 295-299 
    Details
    ISSN: 1432-072X
    Keywords: Clostridium acidiurici ; Clostridium cylindrosporum ; Tungsten uptake ; Molybdate antagonism ; Formate dehydrogenase ; Tungsten-binding-storage protein
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Uptake of tungstate by growing cells was unaffected by the presence of molybdate in Clostridium cylindrosporum, whereas in C. acidiurici the accumulation was decreased by molybdate at 10-6 mol/l tungstate and higher concentrations. The labelling pattern of soluble proteins by 185W-tungsten indicated after gel chromatography the presence of three different tungstoproteins in both bacteria. Formate dehydrogenase activity always eluted at a maximum of tungsten labelling. The incorporation of tungsten into formate dehydrogenase containing fractions and a possible tungsten-binding-storage protein was independent of the presence of excess molydate pointing to a genuine role for tungstate in these bacteria.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00463491
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Three-dimensional organization of the plasmalemmal vesicular system in directly frozen capillaries of the rete mirabile in the swim bladder of the eel (1988)
    Springer
    Cell & tissue research 254 (1988), S. 17-24 
    Details
    ISSN: 1432-0878
    Keywords: Endothelium ; Swim bladder ; Capillaries ; Vesicles ; Ultrastructure ; Cryofixation ; Anguilla rostrata (Teleostei)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Several recent studies comparing chemically fixed and cryofixed endothelium have indicated that glutaraldehyde fixation may result in increases in the population of “vesicles” in the cytoplasm. Other reports based on ultrathin serial-section reconstruction of chemically fixed endothelium have revealed that the vesicular system is comprised of interconnected membranous compartments, which are ultimately continuous with either cell surface but do not extend across the endothelial cell. In this study, we have investigated the three-dimensional organization of the vesicular system in directly frozen, freeze-substituted capillaries of the rete mirabile from the swim bladder of the eel, specifically using the same block of embedded capillaries in which frozen capillaries had previously been found to contain less “vesicles” than chemically fixed capillaries. The results show that essentially all vesicles remain inter-connected with each other and are part of two separate sets of invaginations from the luminal and abluminal cell surface like in chemically fixed tissue. Any increase in vesicle number resulting from glutaraldehyde fixation does not affect the overall three-dimensional organization of the vesicular system in these endothelial cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00220012
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Sleep and benzodiazepine receptor sub-types (1987)
    Springer
    Journal of neural transmission 70 (1987), S. 329-336 
    Details
    ISSN: 1435-1463
    Keywords: Sleep ; benzodiazepines ; CL 218,872
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary CL 218,872, which preferentially binds to benzodiazepine (BZ) type 1 receptors, and flurazepam, which is thought to bind to both types 1 and 2, were given alone and in combination to rats. CL 218,872 had little effect on sleep latency, but significantly increased total sleep time. As expected, flurazepam both shortened sleep latency and prolonged total sleep. Pretreatment with CL 218,872 had no effect on these alterations in sleep induced by flurazepam. The implications for possible significance of sub-typing of BZ receptors are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01253607
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    Paper (German National Licenses)
    Fulltext
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