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  • Electronic Resource  (2)
  • 1985-1989  (2)
  • Life and Medical Sciences  (1)
  • Rheumatoid arthritis  (1)
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  • Electronic Resource  (2)
Years
  • 1985-1989  (2)
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Keywords
  • 1
    Electronic Resource
    Electronic Resource
    Antigen-induced tenosynovitis in hypersensitized rabbits: a model for rheumatoid tenosynovitis (1988)
    Springer
    Rheumatology international 8 (1988), S. 47-53 
    Details
    ISSN: 1437-160X
    Keywords: Rabbit ; Tenosynovitis ; Antigen ; Tendon ; Rheumatoid arthritis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Rabbits were first immunized and later challenged with the same antigen (bovine serum albumin, or ferritin) by injection into the tibialis anterior tendon. Inflammatory changes of the tenosynovium and epitenon included infiltration by neutrophils (early) and mononuclear cells (later) over a 6-week course of tenosynovitis. A pattern of antigen entrapment in the tendon together with immunoglobulin was shown by use of radiolabelled antigen and immunochemical staining. Half-life of antigen in the tissues averaged 5 days over the 6-week period. Changes in the epitenon included cellular necrosis, appearance of phagocytic cells, and disruption of the collagen matrix. Tissues of control animals (challenged without prior immunization) showed minimal changes and significantly less retention of antigen (P〉0.005). The model is relevant to the mechanism of tendon damage associated with antigen-driven chronic inflammation, as may be the case in rheumatoid arthritis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00271834
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Letters to the edior (1986)
    Hoboken, NJ [u.a.] : Wiley-Blackwell
    Journal of Orthopaedic Research 4 (1986), S. 129-131 
    Details
    ISSN: 0736-0266
    Keywords: Life and Medical Sciences
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jor.1100040117
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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