Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • Electronic Resource  (2)
  • 1980-1984  (2)
  • Idiopathic hypoalbuminemia  (2)
Source
Material
  • Electronic Resource  (2)
Years
  • 1980-1984  (2)
Year
Keywords
  • 1
    Electronic Resource
    Electronic Resource
    Turnover of autologousα 1-antitrypsin in a patient with congenital analbuminemia (1983)
    Springer
    Journal of molecular medicine 61 (1983), S. 547-552 
    Details
    ISSN: 1432-1440
    Keywords: Analbuminemia ; α 1-Antitrypsin-turnover ; Idiopathic hypoalbuminemia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Despite very low amounts of albumin (1.7 mg/100 ml) the total plasma protein concentration of a patient with congenital analbuminemia was only slightly reduced to 6.3 g/100 ml. The lack of albumin is compensated by high concentrations of many other plasma proteins. Among the plasma proteins measured,α 1-antitrypsin showed a particularly high level. To investigate the underlying mechanism of this increase we purified plasmaα 1-antitrypsin from the patient, labelled it with125I, and studied its turnover in the analbuminemic patient and two normal volunteers. A half-life of 15 days in the patient compared with 7.5 and 8 days in the normal volunteers was found. The calculated synthesis rate ofα 1-antitrypsin was about twice as high in the patient as in the controls. Therefore, both a longer half-life and an increased synthesis rate contribute to the high level ofα 1-antitrypsin in the plasma of the analbuminemic patient.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01486844
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Analbuminemia (1983)
    Springer
    Journal of molecular medicine 61 (1983), S. 541-545 
    Details
    ISSN: 1432-1440
    Keywords: Analbuminemia ; Idiopathic hypoalbuminemia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Analbuminemia (idiopathic hypoalbuminemia) is a rare congenital anomaly of albumin characterised by very low levels of this protein. Only 21 cases have been reported in the literature. The lack of albumin is “compensated” by increased amounts of various circulating plasma proteins. Other not well understood regulatory mechanisms are responsible for the absence of severe clinical consequences. Clinical aspects, genetics and pathophysiology of this disease are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01486843
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...