ISSN:
1573-3297
Keywords:
linkage
;
X chromosome
;
lod score
;
quantitative character
;
major gene
;
marker locus
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Psychology
Notes:
Abstract A sequential lod-score method is proposed for detecting linkage on the X chromosome between a marker locus and the locus of a major gene influencing a quantitative trait. The method uses information from sons of doubly heterozygous mothers. The average number of families required to detect linkage is substantially less than that of the fixed sample-size method proposed by Hill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01071297
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