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  • Electronic Resource  (12)
  • 1975-1979  (12)
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  • Electronic Resource  (12)
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  • 1
    Electronic Resource
    Electronic Resource
    Argon laser with wall stabilized transverse discharge (1977)
    Springer
    Applied physics 14 (1977), S. 193-197 
    Details
    ISSN: 1432-0630
    Keywords: 42.55 ; 52
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract Planar and cylindrical discharges for argon lasers are compared by plasmatheoretical calculations. The maximum laser output power available in the two arrangements is computed in dependence of various parameters neglecting saturation mechanisms. A transverse discharge arrangement confining the positive column by two parallel walls is described and experimental laser threshold values for the current and pressure are reported.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00883089
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  • 2
    Electronic Resource
    Electronic Resource
    Axial and radial ion movement in the plasma of an ion laser (1976)
    Springer
    Applied physics 10 (1976), S. iii 
    Details
    ISSN: 1432-0630
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00929523
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  • 3
    Electronic Resource
    Electronic Resource
    Liposomen als Träger für Methotrexat (1977)
    Springer
    Journal of cancer research and clinical oncology 90 (1977), S. 187-195 
    Details
    ISSN: 1432-1335
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Medikamente, die in Liposomen (künstliche Lipidvesikel) eingeschlossen sind, haben nach intravenöser Applikation eine andere Pharmakokinetik als Medikamente, die in freier Form injiziert werden. Am Beispiel des Folsäureantagonisten Methotrexat (MTX) wird gezeigt, daß es möglich ist, MTX in einer therapeutisch verwendbaren Dosis (0,5 mg MTX/ml Liposomenlösung pro Injection) in Liposomen einzuschließen und bei hoher Stabilität des Einschlusses zu lagern. Nach intravenöser Injektion in die Schwanzvene von Mäusen wird in Liposomen verkapseltes Methotrexat in Zellsystemen mit hoher Endocytoserate angereichert und nicht wie freies Methotrexat sofort wieder über die Nieren ausgeschieden. Es wird für die Organe Leber, Milz, Nieren, Darm, Lunge und Blut gezeigt, daß es über einen Zeitraum von 6 Std zu einer unterschiedlichen Anreicherung von Methotrexat im Gewebe nach Einschluß von Methotrexat in Liposomen kommt, und daß z. B. nach 6 Std die MethotrexatKonzentration in der Leber um den Faktor 20 höher ist als bei frei injiziertem Methotrexat.
    Notes: Summary Drugs entrapped in liposomes (artifical lipid vesicles) exhibit different pharmacokinetics after intravenous application than drugs injected in a free form. The folidacidantagonist methotrexate can be entrapped in liposomes in a therapeutically useful concentration (0.5 mg MTX/ml) and can be stored with high stability of entrappment. After intravenous injection into the tail vein of mice liposomes entrapped methotrexate is found more enriched in cell systems with high rate of endocytosis and not eliminated by the kidneys within 3 h like free methotrexate. It can be shown, that for the organs liver, spleen, kidney, gut, lung, and blood over a 6 h period liposomes entrapped methotrexate is enriched in the tissues and that for example after 6 h the methotrexate level in the liver is 20 fold higher in comparison to free injected methotrexate.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00285325
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  • 4
    Electronic Resource
    Electronic Resource
    Temperature distribution in tissue during laser irradiation (1978)
    Springer
    Radiation and environmental biophysics 15 (1978), S. 277-287 
    Details
    ISSN: 1432-2099
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Physics
    Notes: Summary During irradiation with an Ar+- and Kr+-laser the temperature rise in living and dead tissue was measured in various depths. The contribution of the blood flow to the heat transport during irradiation was found to be small. The influence of the different depths of penetration and backscattering at the blue-green Ar+- and the red Kr+-radiation was investigated. The measurements compared with theory show reasonable agreement for an one-dimensional model below 100° C. The results are discussed with respect to laser application in medicine.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02176795
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  • 5
    Electronic Resource
    Electronic Resource
    Laserchirurgie an der unteren Nasenmuschel, der Zunge und des Stimmbandes in vitro beim Menschen (1977)
    Springer
    European archives of oto-rhino-laryngology and head & neck 216 (1977), S. 536-536 
    Details
    ISSN: 1434-4726
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Using an argonlaser with a power of 1–100 W experiments on incision and coagulation of tissue are described for different focussing conditions. The laser power for performing laser surgery on the lower human turbinates, the tongue and the vocal cords is determined. For laser application on the turbinates a power of 2 W is sufficient for coagulation of tissue. Higher powers are necessary for laser incision of the tongue. The bloodless procedure is demonstrated in animal experiments performing a hemiglossectomy on the tongue of the anesthezised rabbit. The advantages of laser surgery are discussed. The macroscopical changes of the tissue after laser irradiation is described and possible clinical applications are mentioned.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00458961
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  • 6
    Electronic Resource
    Electronic Resource
    Erste klinische Erfahrungen mit dem Argonlaser bei der Rhinopathia vasomotorica (1977)
    Springer
    European archives of oto-rhino-laryngology and head & neck 216 (1977), S. 632-634 
    Details
    ISSN: 1434-4726
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The construction of a laser-beam-guide system for application in the nasal cavity is presented. An Ar+-laser beam of 1–3 W is conducted to the end tube of 4 mm diameter using two movable arms connected with two rotating mirrors. The beam diameter at the exit of the system is 0.7 mm. The technical procedure for the application of the laser beam on the lower human turbinates is described. Only surface anesthesia was necessary, and no bleeding occured. Over all the time of observation of 6 months, the patients were free of symptoms. The laser procedure is compared with other surgical techniques. Further, the morphological changes after laser irradiation and the symptomatology of laser surgery in the case of vasomotor rhinitis is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00459031
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  • 7
    Electronic Resource
    Electronic Resource
    Quantum mechanics of electromagnetically bounded spin-1/2 particles in expanding universes: II. Energy spectrum of the hydrogen atom (1978)
    Springer
    General relativity and gravitation 9 (1978), S. 489-500 
    Details
    ISSN: 1572-9532
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Completing the preceding paper, the energy spectrum of the hydrogen atom in expanding Robertson-Walker universes is studied in detail using rigorous methods of functional analysis. Thereby, for closed universes (spherical case,ε=1), the corresponding electromagnetic field needs special considerations. For the hyperbolic case (ε=−1) it is shown (a) that the Hamilton operator is uniquely self-adjoint, (b) that the continuous energy spectrum agrees with the one in 4-flat space-time and that the energy eigenvalues are bounded by±m 0 , (c) that they approach Minkowski space spectrum for increasing curvature radius, and (d) that the hydrogen atom cannot be used as an atomic clock showing proper time. For the spherical case (ε=1) it is shown (a) that the Hamilton operator is uniquely self-adjoint and (b) that the energy spectrum is solely discrete.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00759543
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  • 8
    Electronic Resource
    Electronic Resource
    Quantum mechanics of electromagnetically bounded spin-1/2 particles in an expanding universe: I. Influence of the expansion (1978)
    Springer
    General relativity and gravitation 9 (1978), S. 243-255 
    Details
    ISSN: 1572-9532
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The quantum mechanically described electron in an external electromagnetic field, both embedded in an expanding universe with shear, is discussed. This is important for the fundamental question if a quantum mechanically treated atomic clock in curved space-time (based on a hydrogen atom) shows proper or gravitational time. Furthermore, contradictory results reported by other authors seem to imply that quantum mechanics cannot be reconciled with curved space-time. It is shown that this is not the case for expanding Robertson-Walker universes. As basis, in this paper a Hilbert space formulation of the problem with special regard to the Hamiltonian is given. The respective influence of the cosmic expansion and the intrinsic and extrinsic curvatures of the cosmic hypersurfaces on bound quantum mechanical systems is treated in general. For the special case of an expanding 3-flat (ε=0) Robertson-Walker universe it is shown that the energy levels of a hydrogen atom agree completely with the one in 4-flat space-time, so that in this case the hydrogen atom can be taken as atomic clock showing proper time.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00759377
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  • 9
    Electronic Resource
    Electronic Resource
    Axial and radial ion movement in the plasma of an ion laser (1975)
    Springer
    Applied physics 8 (1975), S. 79-84 
    Details
    ISSN: 1432-0630
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract This paper presents a theory of ion movement in the plasma of a cw ion laser considering all ions in a cross-section of the discharge tube collectively. Results are given for an experimental study of the profile of the spontaneous emission of the ArII-4880 Å line under optimal lasing conditions up to the region of output power saturation. A comparison of calculated and experimental results with respect to line shape, line width or temperature, and line shift shows satisfactory agreement.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00883675
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  • 10
    Electronic Resource
    Electronic Resource
    An assay of somatic recombination in male recombination lines of Drosophila melanogaster (1978)
    Springer
    Genetica 49 (1978), S. 77-80 
    Details
    ISSN: 1573-6857
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00187816
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