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  • Digitale Medien  (8)
  • Diaphragm pacing  (3)
  • Ultrastructure  (3)
  • Action potential  (2)
  • 1
    Digitale Medien
    Digitale Medien
    An experimental study on the isolated lateral semicircular canal of the bull frog (1986)
    Springer
    European archives of oto-rhino-laryngology and head & neck 243 (1986), S. 27-30 
    Details
    ISSN: 1434-4726
    Schlagwort(e): Bull frog ; Lateral semicircular canal ; Action potential ; Crista ; Time constant
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary We used isolated lateral semicircular canals from the bull frog, Rana catesbeiana. The cupula was removed from the crista and a glass micropipette was used to depress the sensory cilia on the crista toward the utricular side. Five points on the crista were selected for stimulation. Decremental time constants of the lateral ampullary nerve action potentials were measured. The longest time constant was obtained from stimulation to the wide portion of the crista. The time constant progressively decreased as the narrow side of the crista was approached. These results indicate that the lateral semicircular canal crista is equivalent to the halved posterior semicircular canal crista in terms of both morphology and physiology.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00457903
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  • 2
    Digitale Medien
    Digitale Medien
    Inner ear damage induced by Mycobacterium fortuitum (1986)
    Springer
    European archives of oto-rhino-laryngology and head & neck 243 (1986), S. 121-125 
    Details
    ISSN: 1434-4726
    Schlagwort(e): Bacterial labyrinthitis ; Ultrastructure ; Mycobacterium ; Mouse
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary We used electron microscopy to investigate Mycobacterium fortuitum -induced changes in the inner ears of mice. We found that the inner and outer hair cells had degenerated and disappeared in the organ of Corti. Changes in the lower turn of the cochlea were more severe than those of the upper turn while the changes of the outer hair cells were more severe than those of the inner hair cells. Disappearance, fusion and ballooning of the sensory hairs were observed in the vestibular organs. The bacterial extract also induced inner ear damage which was similar to that caused by live M. fortuitum.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00453763
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  • 3
    Digitale Medien
    Digitale Medien
    Ultrastructural localization of carbonic anhydrase in the vestibular end organs of the guinea pig (1989)
    Springer
    European archives of oto-rhino-laryngology and head & neck 246 (1989), S. 56-60 
    Details
    ISSN: 1434-4726
    Schlagwort(e): Carbonic anhydrase ; Vestibular organ ; Guinea pig ; Histochemistry ; Ultrastructure
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Carbonic anhydrase activity was demonstrated cytochemically on an ultrastructural level in the vestibular end organs of the guinea pig. Reaction product was found in the dark cells, transitional cells, cells of the planum semilunatum and supporting cells. In the dark cells, reaction product was observed in the cytoplasm as well as in the basal infoldings. Reaction product was also observed in the basal infoldings of the transitional cells and the cells of the planum semilunatum. The globular structures inside the supporting cells, transitional cells and the cells of the planum semilunatum were also surrounded by the reaction product. These findings suggest that carbonic anhydrase may have different functions, such as water and ion transport, respiration, nutrition and calcium carbonate deposition in the vestibular end organs.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00454136
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  • 4
    Digitale Medien
    Digitale Medien
    Three-dimensional ultrastructure of the endolymphatic sac (1987)
    Springer
    European archives of oto-rhino-laryngology and head & neck 244 (1987), S. 117-122 
    Details
    ISSN: 1434-4726
    Schlagwort(e): Endolymphatic sac ; Guinea pig ; Scanning electron microscope ; Ultrastructure
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary The subcellular structures of the epithelial cells of the guinea pig endolymphatic sac were studied. By using a newly developed scanning electron microscopy technique, the intracellular organelles could be studied three-dimensionally and the topographic relationships analyzed. The light epithelial cell has an extensive network of endoplasmic reticulum which is characteristically arranged in a basoapical direction. The connections between the inner surface of the plasmalemma and the endoplasmic reticulum were observed, as were connections between the Golgi complex and the endoplasmic reticulum. Our findings support the hypothesis that the endoplasmic reticulum might form transcellular channels through which the cell can transport water and ions from the lumen of the endolymphatic sac out into the subepithelial tissue. The dark epithelial cells seen in particular contained the smooth type of endoplasmic reticulum. Lysosomes were also observed in the dark cells, indicating that these cells probably have more of a secretory function.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00458561
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  • 5
    Digitale Medien
    Digitale Medien
    An experimental study demonstrating the physiological polarity of the frog's utricle (1987)
    Springer
    European archives of oto-rhino-laryngology and head & neck 244 (1987), S. 215-217 
    Details
    ISSN: 1434-4726
    Schlagwort(e): Action potential ; Utricular nerve ; Striola ; Cupula ; Physiological polarity
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary The frog Rana nigromaculata was used as an experimental model. The utricle and its nerve were isolated with the anterior and the lateral semicircular canal ampullae in frog Ringer's solution. The utricular otoconia and the otoconial membrane were then carefully removed. The halved anterior canal cupula was next placed in the tip of a glass microelectrode, which was mounted on a micromanipulator. The cupula was placed in the center of either the medial or the lateral part of the macula and was moved toward or away from the striola along the axis vertical to the striola. When the medial part of the macula was stimulated, 5 μm of striolapetal cupular movement elicited an excitatory nerve discharge. When the lateral part of the macula was stimulated, the striolapetal stimulus likewise induced an excitatory response. These results indicate the existence of physiological polarity on the utricular macula.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00455308
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  • 6
    Digitale Medien
    Digitale Medien
    A heart-rate-responsive diaphragm pacemaker (1987)
    Springer
    Medical & biological engineering & computing 25 (1987), S. 458-462 
    Details
    ISSN: 1741-0444
    Schlagwort(e): Diaphragm pacing ; Exercise responsive ; Heart rate ; Microcomputer ; Pacemaker ; Stimulator ; Ventilation support
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Chemie und Pharmazie , Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02443369
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  • 7
    Digitale Medien
    Digitale Medien
    Addition to an RF-coupled phrenic nerve stimulator implant to provide outward transmission of body temperature (1986)
    Springer
    Medical & biological engineering & computing 24 (1986), S. 659-661 
    Details
    ISSN: 1741-0444
    Schlagwort(e): Diaphragm pacing ; Pacemaker ; RF ; Telemeter ; Temperature
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Chemie und Pharmazie , Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02446273
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  • 8
    Digitale Medien
    Digitale Medien
    Heart rate and body temperature sensitive diaphragm pacing (1992)
    Springer
    Medical & biological engineering & computing 30 (1992), S. 155-161 
    Details
    ISSN: 1741-0444
    Schlagwort(e): Diaphragm pacing ; Exercise ; Physiological pacing ; Rate responsive
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Chemie und Pharmazie , Medizin
    Notizen: Abstract Two ways of rate control for diaphragm pacing are proposed. One is rate control using only the patients' body temperature (method I). The other is rate control by both the patients' heart rate and body temperature (method II). To test the effectiveness of these methods, a diaphragm pacemaker which can be controlled by both heart rate and body temperature has been developed. It was applied to nine mongrel dogs. The pacing rate is controlled by atrial blood temperature (method I) or by both heart rate and temperature (method II). The animal's metabolism was elevated by the administration of a pyrogenic drug. It was found that method I is not suited to rapid changes in metabolism; however, it is useful in extreme metabolic elevation. An animal's metabolism was supported by using method II in all ranges of metabolism. This method proved more effective than method I for rate-responsive diaphragm pacing.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02446125
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