ISSN:
1438-2199
Keywords:
Amino acids
;
Monosodium glutamate
;
Glutamate dehydrogenase
;
Aminotransferases
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Glutamate (Glu) the major amino acid in mammalian brain and most dietary proteins possesses neurotransmitter as well as neurotoxic properties. We administered monosodium glutamate (MSG) 4 mg/g bwt, sc on postnatal day (PND) 1 through 10 to rats on alternate days or daily and sacrificed them on PND 45 or PND 90 respectively. The activities of glutamate dehydrogenase and aminotransferases were evaluated in the circumventricular organs of brain. Results show that neonatal MSG produces alterations in glutamate metabolism in blood-brain-barrier deficient regions.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00806557
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