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  • Electronic Resource  (5)
  • Bone marrow transplantation  (2)
  • Inorganic Chemistry  (2)
  • Analytical Chemistry and Spectroscopy  (1)
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  • Electronic Resource  (5)
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  • 1
    ISSN: 1432-0584
    Keywords: Key words Interleukin-6 ; Aplasia ; Bone marrow transplantation ; Hematopiesis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  Interleukin-6 (IL-6) has been shown to be an inducer of the acute-phase response (APR) and to be involved in the pathogenesis of several disease states, including graft-versus-host disease (GvHD) following allogeneic bone marrow transplantation (BMT). As blood cells of the monocyte lineage are known to be major producers of this cytokine, we wondered whether extreme peripheral leukopenia following total ablation of hematopoiesis could compromise IL-6 production during the first days after allogeneic or autologous BMT. In the absence of detectable circulating leukocytes we measured elevated IL-6 levels in six children having fever (≥38°  C) of presumed infectious origin with an average of 74±60 units/ml (range 19–309 units/ml). IL-6 levels in febrile children having a normal hematopoiesis (118±254 units/ml, range 17–1213 units/ml) were not significantly higher than those found in the febrile BMT group (p〉0.05). Moreover, there was a clear association between elevated IL-6 levels and the presence of fever. C-reactive protein (CRP) was also elevated (≥1 mg/dl), whereas tumor-necrosis factor alpha (TNF) was undetectable (〈1 pg/ml). Two transplanted patients without fever during the period of total aplasia had neither detectable CRP nor IL-6, thus demonstrating that the transplant procedure itself does not induce an APR. Our data obtained during maximal leukopenia following BMT show that a functional hematopoietic system is not necessary for regular production of IL-6, which is associated with fever. Cells of nonhematopoietic origin may contribute to this production.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-0584
    Keywords: Interleukin-6 ; Aplasia ; Bone marrow transplantation ; Hematopiesis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Interleukin-6 (IL-6) has been shown to be an inducer of the acute-phase response (APR) and to be involved in the pathogenesis of several disease states, including graft-versus-host disease (GvHD) following allogeneic bone marrow transplantation (BMT). As blood cells of the monocyte lineage are known to be major producers of this cytokine, we wondered whether extreme peripheral leukopenia following total ablation of hematopoiesis could compromise IL-6 production during the first days after allogeneic or autologous BMT. In the absence of detectable circulating leukocytes we measured elevated IL-6 levels in six children having fever (≥38° C) of presumed infectious origin with an average of 74±60 units/ml (range 19–309 units/ml). IL-6 levels in febrile children having a normal hematopoiesis (118±254 units/ml, range 17–1213 units/ml) were not significantly higher than those found in the febrile BMT group (p〉0.05). Moreover, there was a clear association between elevated IL-6 levels and the presence of fever. C-reactive protein (CRP) was also elevated (≥1 mg/dl), whereas tumor-necrosis factor alpha (TNF) was undetectable (〈1 pg/ml). Two transplanted patients without fever during the period of total aplasia had neither detectable CRP nor IL-6, thus demonstrating that the transplant procedure itself does not induce an APR. Our data obtained during maximal leukopenia following BMT show that a functional hematopoietic system is not necessary for regular production of IL-6, which is associated with fever. Cells of nonhematopoietic origin may contribute to this production.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Chichester : Wiley-Blackwell
    Organic Magnetic Resonance 31 (1993), S. 352-356 
    ISSN: 0749-1581
    Keywords: Separated-local-field NMR ; Chemical-shift tensor orientations ; Poly(ethylene oxide) ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The 13C chemical-shift tensor orientations in the OCH2CH2O moieties of poly(ethylene oxide) (PEO) and poly(ethylene terephthalate) (PET) were determined by means of 1H—13C separated-local-field NMR spectroscopy, and the literature values for the shift tensors in polyethylene (PE) and polyoxymethylene (POM) were improved. An angular resolution of ± 4° was attained on standard equipment with 90° pulse lengths exceeding 4 μs. Relatively high uniformity of the methylene tensor orientations, complying with local molecular symmetry, was found.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 424 (1976), S. 5-12 
    ISSN: 0044-2313
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: On Oxopalladates of Alkali MetalsAccording to X-ray data of single crystals there are: Na2PdO2 (yellow rod-shaped crystals) orthorhombic, a = 3.077, b = 10.359, c = 8.351 Å, Z = 4; dx = 4.60, dpyk = 4.63 g · cm-3. „K2PdO3“ (black square prism) orthorhombic, a = 6.202, b = 9.219, c = 4× 11.372 = 45.48 Å, Z = 24, dx = 3.60, dpyk = 3.50 g · cm-3, and „K6PdO4“ (orange square prism) orthorhombic (pseudotetragonal), a = b = 12.368, c = 13.593 Å, Z = 8, D24 - P212121.„Rb2PdO3“ (black) is isostructural (Guinier data) to „K2PdO3“, a = 7.354, b = 9.605, c = 11.586 Å, dx = 4.58, dpyk = 4.47 g · cm-3. Na2PdO3 exists in another reddish brown form, isostructural to Li2MnO3 (C2h6 - C2/c), a = 5.374, b = 9.309, c = 10.789 Å, β = 99.5°, Z = 8, dx = 5.00, dpyk = 4.73 g · cm-3.
    Notes: Orthorhombisch kristallisieren nach Einkristalldaten Na2PdO2 (gelbe Stäbchen), C2v12-Cmc21 oder D2h17 - Cmcm mit a = 3,077, b = 10,359, c = 8,351 Å, Z = 4, drö = 4,60 und dpyk = 4,63 g · cm-3, „K2PdO3“ (schwarze quadratische Säulen) mit a = 6,202, b = 9,219, c = 4× 11,371 = 45,48 Å, Z = 24, drö = 3,60 und dpyk = 3,50 g · cm-3 und „K6PdO4“ (orangerote quadratische Säulen) (pseudotetragonal) mit a = b = 12,368, c = 13,593 Å, Z = 8, D24 - P212121.„Rb2PdO3“ (schwarz) ist nach Guinier-Daten isotyp mit „K2PdO3“, a = 6,354, b = 9,309, c = 11,586 Å, drö = 4,58 und dpyk = 4,47 g · cm-3. Von Na2PdO3 existiert eine weitere rotbraune Form, die mit Li2MnO3 (C2h6 - C2/c) isotyp ist, a = 5,374, b = 9,309, c = 10,789 Å, β = 99,5°, Z = 8, drö = 5,00 und dpyk = 4, 73 g · cm-3.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 409 (1974), S. 60-68 
    ISSN: 0044-2313
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: The Oxopalladate Na2Pd3O4Hithertoo unknown Na2Pd3O4 was prepared. The black rod-shaped single crystals are orthorhombic, a = 3.043, b = 5.446, c = 13.175 Å, drö = 6.50 g · cm-3, dpyk = 6.43 g · cm-3, D252h-I mmm. For parameters see text.There are Pd3O4 double-layers normal to [001], which are connected with eachother by Na in a trigonal prismatic coordination. The MADELUNG part of lattice energy (MAPLE) is calculated for Na2Pd3O4 and compared with those of the binary oxids. MAPLE for a hypo-thetical form of Pd3O4 is discussed in comparison to the “isolated” double-layer Pd3O4.
    Notes: Neu dargestellt wurde Na2Pd3O4, der erste Vertreter von Oxiden des Palladiums dieses Formeltyps. Die schwarzen stäbchenförmigen Kristalle kristallisieren orthorhombisch mit a = 3,043, b = 5,466, c = 13,175 Å, drö = 6,50 g · cm-3, dpyk = 6,43 g · cm-3 Z = 2 in D252h-I mmm; Punktlagen und Parameter vgl. Text.Es liegen Pd3O4-Doppelschichten senkrecht zu [001] vor, die durch Na in trigonalprismatischer Koordination miteinander verbunden werden. Der MADELUNQ- Anteil der Gitterenergie, MAPLE, wird für Na2Pd3O4 berechnet und mit denen der binären Oxide verglichen. Diskutiert wird ferner MAPLE für eine hypothetische Form von Pd3O4 im Vergleich MAPLE für die “isolierte” Doppelschicht Pd3O4.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
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