ISSN:
1434-9949
Keywords:
Cytophagic Histiocytic Panniculitis
;
Weber-Christian Disease
;
Steroid Pulse Therapy
;
Cyclosporine A
;
Ferritin
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary We report a 35-year-old man, who had been diagnosed with Weber-Christian disease, presented with acute onset of high fever, malaise, jaundice and hepatosplenomegaly with subcutaneous nodules. Laboratory tests showed elevated serum ferritin and liver enzymes, especially lactate dehydrogenase (LDH), with pancytopenia and coagulation abnormalities. Peripheral blood and bone marrow examinations showed erythro-, leuko- and thrombo-phagocytic histiocytes and macrophages. The patient developed the same clinical features seven years ago. Based on diagnosis of cytophagic histiocytic panniculitis, the patient was treated with steroid pulse therapy and oral cyclosporin A. The combination therapy caused a marked improvement in the clinical condition.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02242462
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