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  • Electronic Resource  (8)
  • Chemistry  (4)
  • Failuremechanisms
  • Flash X-rays
  • Propranolol ester derivatives
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Colloid & polymer science 270 (1992), S. 659-666 
    ISSN: 1435-1536
    Keywords: Failuremechanisms ; high-impactpolystyrene ; short-fiber-reinforcedthermoplastics ; rubberparticles ; craze-controlledcracking
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract Injection-molded, short-glass-fiber-reinforced high-impact polystyrene was investigated under uniaxial tension with special attention to the effects of fiber and rubber concentration on fracture behavior. According to a fracture morphology study performed by polarized optical and scanning electron microscopy, crazes were consecutively initiated from rubber-styrene composite particles and from fiber ends. The rubber particles exhibited an intra-particle failure mode which resulted from the failure manner of the matrix becoming of a more brittle character with increasing fiber fraction. Fibers were surrounded by neigh boring growing crazes. Failure at the fiber-matrix interfaces proceeded with an increase in the number of crazes. With increasing concentration of the fibers, crazing at rubber particles appeared to be suppressed and crazing occurred more preferentially at the fiber ends, which accelerated a macroscopic fracture.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1612-1112
    Keywords: Column liquid chromatography ; Chiral separation ; Alpha 1-acid glycoprotein-bonded column ; Propranolol ; Propranolol ester derivatives
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Summary The retention, enantionselectivity and enantiomeric elution order of racemic propranolol (PP) and its ester derivatives (O-acetyl,-propionyl,-butyrul and-valeryl PP) on an α1-acid glycoprotein (AGP)-bonded column have been investigated by changing eluent composition (eluent pH, buffer concentration, type and content of organic modifier). The retention of these cationic solutes, PP and its ester derivatives, was influenced by eluent pH, ionic strength and organic modifier content. The enantioselectivity was dependent on eluent pH and type of organic modifier. Reversal of the enantiomeric elution order of ester derivatives of PP (O-propionyl-butyryl) and-valeryl PP) occurred around eluent pH 6–7. These results suggst that chiral recognition or binding properties may be altered by the change in eluent composition, espeically eluent pH and type of organic modifier.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1612-1112
    Keywords: Column liquid chromatography ; Ovomucoid-bonded silica ; Chiral separation ; Propranolol ; Propranolol ester derivatives
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Summary The retention, enantioselectivity and enantiomeric elution order of racemic propranolol (PP) and its ester derivatives (O-acetyl,-propyl,-butyl and-valeryl PP) on an ovomucoid-bonded silica column have been investigated with respect to pH, ionic strength and organic modifier. For these cationic solutes, an increase in the organic modifier content and/or a decrease in the pH result in a decreased retention of both enantiomers. Enantioselectivity of the ester derivatives was higher than of underivated PP. The enantiomeric elution order was (S)/(R) for PP and (R)/(S) for the four ester derivatives, when ethanol or 2-propanol was used as the organic modifier. When methanol or acetonitrile was used as the organic modifier, inversion of the enantiomeric elution order was observed for O-valeryl PP with the use of methanol and for PP and O-propyl PP with acetonitrile. These results suggest that at least two chiral binding- or recognitionsites are present in a protein molecule and/or conformational changes occur in the chiral binding- or recognition-site(s) of the protein molecule bonded to a silica matrix.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 17 (1971), S. 1141-1152 
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Additional Material: 12 Ill.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Medical & biological engineering & computing 31 (1993), S. S37 
    ISSN: 1741-0444
    Keywords: Cold-cathode diode ; Disk cathode ; Flash X-rays ; Photon energy control ; Pulsed X-rays ; Tube current control
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract Fundamental studies of a repetitive flash X-ray generator using a diskcathode radiation tube are described. The high-voltage pulser employed a modified two-stage surge-Marx circuit. The two condensers in the pulser were charged from 40 to 60 kV, and the electric charges were discharged to the X-ray tube repetitively to generate flash X-rays. The total capacity during the main discharge was 425 pF, and the maximum output voltage from the pulser was about 1·9 times the charged voltage. The flash X-ray tube of the demountable-diode type and was composed of a rodshaped anode tip made of tungsten, a disk cathode made of graphite and a tube body made of polymethylmethacrylate. The peak tube voltage was primarily determined by the anode-cathode (A-C) space, and the peak tube current was less than 0·5 kA. Thus the maximum photon energy could be easily controlled by varying the A-C space, and the tube current roughly increased according to increases in the charged voltage. The pulse width ranged from 40 to 100 ns, and the X-ray intensity was less than 1·1 μC kg−1 at 0·5 m per pulse. The repetition rate was less than 50 Hz, and the effective focal spot size was equivalent to the anode diameter.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    New York : Wiley-Blackwell
    Biopolymers 27 (1988), S. 1917-1925 
    ISSN: 0006-3525
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Adiabatic differential scanning microcalorimetry, which provides curves of the heat capacity vs temperature, was carried out for the DNA of plasmid pJL3-TB5 (5277 base pairs in length). The calorimetry curve shows nine peaks ranging from 81 to 96°C in 1 × SSC buffer at a heating rate of 0.25°C, due to the stepwise helix-coil transition of the DNA along the molecular chain. The theoretical melting curve, which can be constructed by calculation from the entire nucleotide sequence of the plasmid DNA by the helix-coil transition theory, is then compared with the calorimetry curve. The two curves resemble each other remarkably well, particularly when a parameter for the methylated adenine residues at GATC sites by Dam methylase is used appropriately. This allows us to assign each peak in the calorimetry curve to the melting of the respective regions of the plasmid DNA sequence. The local stability of the helix-coil transition along the DNA chain is closely related to the functional regions coded by pJL3-TB5, such as genes, transcriptional promoters, and particular sites generated by recombination of two different sequences in vivo and in vitro.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Stamford, Conn. [u.a.] : Wiley-Blackwell
    Polymer Engineering and Science 27 (1987), S. 25-32 
    ISSN: 0032-3888
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Ultrasonic fractography studies were performed on poly(methyl methacrylate) of high molecular weight. The transient fracture velocity change at the slow-to-fast transition during discontinuous propagation has been measured precisely. Fast fracture starts with a characteristic velocity which falls in a narrow range between 90 to 150 m/s, nearly independent of the loading speeds and the specimen temperature from -50 to 40°C. Parallel double-cantilever-beam specimens exhibited stick-slip type propagation whose velocity change was also evaluated. In these specimens, the fast fracture abruptly slows down to speeds on the order of 10° m/s. These intermediate velocities have never been obtained in the slow-to-fast transition. Velocity measurements under hydrostatic pressure have shown that fracture velocities decrease significantly with increasing pressure, and that the slow-to-fast transition tends to disappear at a pressure between 5 and 10 MPa. Models have been presented concerning the mechanism of the slow-to-fast transition, crazing and cracking under superposed cyclic stress field, and the relationship between dynamic toughness and fracture velocity in this material.
    Additional Material: 14 Ill.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Chichester [u.a.] : Wiley-Blackwell
    Surface and Interface Analysis 24 (1996), S. 711-717 
    ISSN: 0142-2421
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Physics
    Notes: The degradation of the surface composition of poly(ethylene terephthalate) (PET) film by ultraviolet light was analysed by ESCA combined with gas chemical modification (GCM) techniques. A new approach for distinguishing phenolic hydroxyl and alcoholic hydroxyl groups was presented, which uses the difference in reactivity of trifluoroacetic anhydride to the phenolic group and to the alcoholic group. The carboxyl group was detected with trifluoroethanol. The ESCA-GCM results showed differences of the chemical composition of the light-facing side and the back side of the PET film. According to photodegradation mechanisms of PET reported by other researchers, carboxyl group formation suggested cleavage of the main chain of PET. The number of the phenolic carbon on the light-facing side corresponded to the existence of 16 phenolic groups per 100 monomeric units.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
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