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  • Electronic Resource  (3)
  • Ejection fraction  (1)
  • Luminometer  (1)
  • Neutrophils  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Rheumatology international 6 (1986), S. 57-60 
    ISSN: 1437-160X
    Keywords: Neutrophils ; Elastase ; Rheumatoid arthritis ; Systemic lupus erythematosus ; Inflammation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Elastase-inhibitor complex (EIC) levels were determined in EDTA-plasma samples of 40 patients with connective tissue disease by a double antibody immunoassay technique. In active rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE), EIC levels were significantly higher than in the normal controls (P〈10−8) and fell on remission. The mean EIC level in active RA was significantly greater than in inactive disease (P=0.0001) but there was no statistically significant difference between the EIC levels in the acute and inactive disease states in SLE (P=0.49). In active RA, there was a positive correlation between EIC levels and white blood cell count (WBC) but not with erythrocyte sedimentation rate (ESR). In SLE there was no significant correlation between EIC levels and ESR or WBC. EIC measurement may be useful in the objective assessment of activity in RA.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-203X
    Keywords: Key wordsOryza sativa ; Luciferase gene ; Transient expression ; luc ; Luminograph ; Luminometer
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Transformed rice plants of var `TN1' were regenerated from immature embryos following particle bombardment with a construct containing the firefly luciferase gene as a reporter gene and the hygromycin resistance gene as a selectable marker. Expression of the luciferase gene in the presence of the substrate luciferin was visualised in the calli derived from bombarded immature embryos and in the leaves and roots of the regenerated transformed plants using a low light imaging system (luminograph). Embryogenic callus proliferation and plant regeneration were unaffected by luciferin treatment and luminograph screening. The quantitative Luc assay using samples of leaf tissue from the segregating generations gave early information about the homozygous and hemizygous state of the luc transgene.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Annals of biomedical engineering 17 (1989), S. 483-494 
    ISSN: 1573-9686
    Keywords: Impedance cardiography ; Stroke volume ; Ejection fraction ; End-diastolic volume ; End-systolic volume ; Intensive care unit ; Review
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Technology
    Notes: Abstract Impedance cardiography has not achieved popularity in the Intensive Care Unit (ICU) to date probably because of the limitations in technique and interpretation associated with the altered physiology of critically ill patients, and also because of interference from other machinery in the ICU. The current climate of questioning the existing technology for bedside cardiovascular assessment however spurs the need to evaluate impedance cardiography as a noninvasive alternative. Validation in noncritically ill patients is good when compared to other technologies (e.g., thermodilution, Fick, dye dilution (r〉0.9)). Reliability is good with a coefficient of variation in an ICU population of 8.9%, (compared to 18.6% for thermodilution). It has also shown promise in detecting the clinically significant changes of central intravascular volume. Impedance cardiography appears to be useful for measurement of stroke volume (SV) and ejection fraction (EF). From these, left ventricular end-diastolic volume (VED) can be calculated, probably a more reliable estimate of left ventricular filling than pulmonary capillary wedge pressure (PW), measured by pulmonary artery (PA) catheter. In addition, VES can be calculated and with the knowledge of left ventricular end-systolic pressure (PES) (from invasive arterial monitoring), an end-systolic pressure-volume (ES-PV) (relationship can be derived. This is thought to be a measure of contractility that is independent of preload and afterload. The ultimate test in the ICU for impedance cardiography is whether clinical outcome of critically ill patients is altered by the use of this technology. Such outcome testing is essential before the true value of impedance cardiography in the management of critically ill patients can be determined.
    Type of Medium: Electronic Resource
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