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Estrogens influence antibody coating in experimental urinary tract infection (1983)

Riedasch, G. ; Setzis, K. ; Bersch, W. ; [et al.]

Springer

Journal of molecular medicine 61 (1983), S. 529-531

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ISSN: 1432-1440

Keywords: Antibody coating ; Urinary tract infection ; Estrogens

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Summary Female rats were infected with E. coli 0.25 by intravesical instillation. After 4 weeks, significantly higher bacterial counts (bladder puncture and renal homogenates) were found in estradiol treated rats (0.5 mg/kg/week) than in solvent controls, but the proportion of antibody-coated bacteria was significantly (P〈0.01) lower in bladder urine and renal homogenates. There was no influence of estrogens on renal histology or ureteral width. The results are compatible with an effect of estrogens on local immune response in the urinary tract.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF01488721

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