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Digitale Medien

Undifferentiated carcinoma of the colon containing exocrine, neuroendocrine and squamous cells (1983)

Damjanov, Ivan ; Amenta, Peter S. ; Bosman, Fred T.

Springer

Virchows Archiv 401 (1983), S. 57-66

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Details

ISSN: 1432-2307

Schlagwort(e): Keratin ; Alpha-1-antitrypsin ; Lysozyme

Quelle: Springer Online Journal Archives 1860-2000

Thema: Medizin

Notizen: Summary The light microscopic, electron microscopic and histochemical features of a highly malignant colonic tumor resected from a 39 year old man are presented. The tumor was composed predominantly of undifferentiated cells, with focally admixed neuroendocrine, exocrine and squamous cells, occasionally arranged in an organoid manner. Histochemically the tumor contained argyrophilic cells as well as cells that reacted positively with the antibodies to alpha-1-antitrypsin, alpha-1-antichymotrypsin, carcinoembryonic antigen and lysozyme. The term “stem cell carcinoma of the intestine” is proposed for this highly malignant tumor composed of undifferentiated cells exhibiting only focally their multidirectional developmental capacity.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00644789

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