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  • 1990-1994
  • 1970-1974  (10)
  • 1971  (1)
  • 1970  (9)
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  • 1990-1994
  • 1970-1974  (10)
Year
  • 1
    Electronic Resource
    Electronic Resource
    COMPARTMENTATION OF CITRIC ACID CYCLE METABOLISM IN BRAIN: LABELLING OF GLUTAMATE, GLUTAMINE, ASPARTATE AND GABA BY SEVERAL RADIOACTIVE TRACER METABOLITES (1970)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 17 (1970), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: —(1) Compartmentation of the metabolism of amino acids in brain has been studied in slices of cerebral cortex incubated with sodium [1-14C]acetate, sodium [1-14C]-bicarbonate, [1-14C]GABA or l-[1-14C]glutamate and in samples of brain after injection in vivo of [1-14C]- or [3H]acetate.(2) The method of treatment of the slices (a) maintained in ice-cold medium prior to incubation; (b) preincubation at 37°C and transfer to fresh medium affected the metabolism of the added, labelled substrate, particularly its labelling of glutamine.(3) The specific activity of glutamine labelled from the above metabolites was greater than that of glutamic acid in experiments of 10–30 minutes duration, whether or not subjected to pretreatment in the cold.(4) Incubation in medium containing 27 mm-K+ was associated with a decrease in the relative specific activity (RSA) of glutamine, except for the increase when l-[1-14C]glutamate was the precursor.(5) The data have been discussed in terms of metabolic compartmentation and their consistency with the concept of the presence in brain of more than one citric acid cycle, one containing the relatively smaller pools of intermediates and associated with synthetic processes; the other containing the relatively larger pools of intermediates and functioning as a homeostatic buffer for energy metabolism.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-4159.1970.tb02254.x
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  • 2
    Electronic Resource
    Electronic Resource
    COMPARTMENTATION OF CITRIC ACID CYCLE METABOLISM IN BRAIN: EFFECT OF AMINOOXYACETIC ACID, OUABAIN AND Ca2+ ON THE LABELLING OF GLUTAMATE, GLUTAMINE, ASPARTATE AND GABA BY [1-14C]ACETATE, [U-14C]GLUTAMATE AND [U-14C] ASPARTATE (1970)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 17 (1970), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: —(1) The effects of aminooxyacetic acid, ouabain and Ca2+ on the compartmentation of amino acid metabolism have been studied in slices of brain incubated with sodium-[1-14C]acetate, l-[U-14C]glutamate and l-[U-14C]aspartate as tracer metabolites.(2) Aminooxyacetic acid (10-3 m) inhibited the labelling of aspartate from [14C]acetate and [14C]glutamate, as well as the incorporation of label from [14C]aspartate into glutamate and glutamine. It also inhibited the labelling of GABA from all three radioactive precursors, as would be anticipated if there was inhibition of several transaminases as well as glutamate decarboxylase. The RSA of glutamine labelled from [1-14C]acetate was increased. This finding indicated that the glutamate pool which is utilized for glutamine formation is associated with glutamate dehydrogenase, and this enzyme appears to be related to the ‘synthetic tricarboxylic acid cycle’. AOAA exerted its major inhibitory effects on the citric acid‘energy cycle’with which transaminases are associated.(3) Ouabain (10-5 m) inhibited the labelling of glutamine to a much greater extent than the labelling of glutamate from [1-14C]acetate. It also caused leakage of amino acids from the tissue into the medium. Its effect on the glutamate–glutamine system was interpreted to be a selective inhibition of the 'synthetic’citric acid cycle.(4) The omission of Ca2+ from the incubation medium was associated with formation of glutamine with RSA less than 1·0 when labelled from [U-14C]glutamate, [U-14C]aspartate and lower than normal when labelled from [1-14C]acetate.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-4159.1970.tb02253.x
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  • 3
    Electronic Resource
    Electronic Resource
    Electric Effects of the Failure of Fibre Reinforced Plastics (1971)
    [s.l.] : Nature Publishing Group
    Nature 230 (1971), S. 322-324 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Mahieu has demonstrated1 that there are electrical and luminescent effects associated with .the failure of glass reinforced resins. He showed that current changes of between 10~12 and 10-10 A occurred both in the direction of the bias current and/or in opposition to it when a tensile specimen was ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/230322a0
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  • 4
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    Unknown
    Mass Terms as Subjects (1970)
    Minneapolis : Periodicals Archive Online (PAO)
    Philosophical Studies. 21:1/2 (1970:Jan./Feb.) 
    Details
    ISSN: 0031-8116
    Topics: Philosophy
    URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:6193-1970-021-01-000007
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  • 5
    Electronic Resource
    Electronic Resource
    Tertiary basalts of Baffin Bay: Possible primary magma from the Mantle (1970)
    Springer
    Contributions to mineralogy and petrology 25 (1970), S. 203-224 
    Details
    ISSN: 1432-0967
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Abstract New analyses show that Tertiary tholeiitic basalts from the Baffin Bay area have generally primitive characteristics. Comparison of the bulk chemical compositions of the basalts with material of known phase relations suggests that these basalts have properties intermediate between investigated natural and synthetic compositions. A discrete group of these basalts coincides in projection with the composition of the liquid produced by the partial melting of garnet periodotite at 30 kb. The compositions in this group are believed to be parental to the other rocks in the province principally through a mechanism of olivine fractionation. Eclogite fractionation is invoked to account for the chemical differences between the two suites of basalts in Baffin Bay.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00371131
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  • 6
    Electronic Resource
    Electronic Resource
    Mass terms as subjects (1970)
    Springer
    Philosophical studies 21 (1970), S. 25-28 
    Details
    ISSN: 1573-0883
    Source: Springer Online Journal Archives 1860-2000
    Topics: Philosophy
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00375978
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    Paper (German National Licenses)
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  • 7
    Electronic Resource
    Electronic Resource
    The effect of glow discharge on insulators as observed in the scanning electron microscope (1970)
    Springer
    Journal of materials science 5 (1970), S. 364-366 
    Details
    ISSN: 1573-4803
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00552290
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  • 8
    Electronic Resource
    Electronic Resource
    The effect of glow discharge on insulators as observed in the scanning electron microscope (1970)
    Springer
    Journal of materials science 5 (1970), S. 364-366 
    Details
    ISSN: 1573-4803
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02397791
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  • 9
    Electronic Resource
    Electronic Resource
    Review: Image contrast in the scanning electron microscope (1970)
    Springer
    Journal of materials science 5 (1970), S. 689-708 
    Details
    ISSN: 1573-4803
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract Already the scanning electron microscope is used extensively in the fields of materials science and the life sciences, but it is still being rapidly developed. This paper is an up-to-date review of the types of contrast that can be detected and of the mechanisms that give rise to them. The effect of the type of collector and display system used is discussed together with the possibility of improving the images to show enhanced contrast.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00549753
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  • 10
    Electronic Resource
    Electronic Resource
    A bend-testing stage for the scanning electron-microscope (1970)
    Springer
    Journal of materials science 5 (1970), S. 873-880 
    Details
    ISSN: 1573-4803
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The design of a stage to bend materials in a scanning electron-microscope (Stereoscan, Cambridge Scientific Instruments Ltd) is described together with examples of its use in the fracture of composite materials. The bend module, when fitted to a large modular stage, can be used with existing scanning electron microscopes and is capable of bending, under increasing load or cyclic loading conditions, rectangular specimens of a maximum size 44×4×1.5 mm, to a maximum strain of 1.5%. Using the module with a standard display system the non-catastrophic stages of deformation and failure can be followed at higher magnification than has previously been possible. When the module is used in conjunction with a fast scanning and display system, deformation and fracture processes may be recorded at high magnifications while the specimen is being strained.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00574859
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