ISSN:
1432-2072
Keywords:
Lysergic Acid Diethylamide
;
Para-Chlorophenylalanine
;
Alpha-Methyl-Para-Tyrosine
;
Operant Conditioning
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract The bar-pressing behavior of hungry rats was maintained by a fixed-ratio schedule of food reinforcement. At 5 and 12 days after pretreatment with p-chlorophenylalanine (PCPA), a subtreshold dose (20 μg/kg) of lysergic acid diethylamide (LSD) was found to disrupt this behavior. No such disruption occurred when PCPA pretreatment was followed by either a distracting external stimulus (tone) or a low dose of D-amphetamine (0.3 mg/kg). Sensitivity to LSD was apparently unaffected by pretreatment with α-methyl-p-tyrosine (AMPT).
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00402765
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