Library

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • 1975-1979
  • 1970-1974  (5)
  • 1960-1964
  • 1970  (5)
Material
Years
  • 1975-1979
  • 1970-1974  (5)
  • 1960-1964
Year
  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 17 (1970), S. 0 
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: 〈list xml:id="l1" style="custom"〉1The rapid and extensive conversion of glucose-carbon into amino acids is an index of the final coordination of the mechanisms underlying energy metabolism in the adult brain. This phenomenon develops in the rat during a short period extending from 10 to about 19 days after birth. The underlying factors have been analysed.〈list xml:id="l2" style="custom"〉2The development of the pattern of distribution of glucose-carbon characteristic of the adult brain was markedly influenced by the thyroid state of the animals. The age-curve for the conversion of glucose-carbon into brain amino acids was displaced to the left after treatment with thyroid hormone (T3) in infancy thus indicating an accelerated maturation. Conversely, neonatal thyroidectomy resulted in a significant retardation in the conversion of glucose-carbon into amino acids.〈list xml:id="l3" style="custom"〉3The specific radioactivity of glutamate increased five-fold in the brain of normal rats from the 10th to the 19th day of age. The values (as a percentage of those for littermate controls) were 220 in the case of the 10 day-old thyroid treated rats and about 30 for the 19 day-old thyroid deficient animals. At the age of 10 days neither treatment affected the concentration of glutamate which was also only slightly less than the control values in the brain of 19 day-old thyroid deficient animals (–17 per cent).〈list xml:id="l4" style="custom"〉4Specific pool(s) of glutamate associated with the formation of GABA can be demonstrated in the brain of 19 day-old rats after administration of [U-14C]glucose as a result of anoxia post mortem. These pools did not develop in the brain of 10 day-old animals. Neonatal thyroidectomy retarded the development of these glutamate pools.〈list xml:id="l5" style="custom"〉5Evidence is summarized which indicates that the development of the rapid conversion of glucose-carbon into amino acids reflects the enlargement, during maturation, of the metabolic compartments which are associated with neuronal processes.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 2
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Industrial and engineering chemistry 9 (1970), S. 304-304 
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 3
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 225 (1970), S. 1173-1173 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] SIR,-It is refreshing to read Mr Bruce Sanford's letter (Nature, 225, 979; 1970) which departs from the usual attitude of burying one's head in the sand in the hope that computers will solve the information explosion problem. Far too often the use of computers is voiced in the context of ...
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Calcified tissue international 6 (1970), S. 103-112 
    ISSN: 1432-0827
    Keywords: Calcium ; Strontium ; Bone ; Exchange ; Equilibrium
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Description / Table of Contents: Résumé La réactivité de l'os de rat envers un contenu faible et élevé de strontium a été étudiée par la technique de l'échange radioisotopique dans des conditionsin vitro bien définies. Des courbes d'absorption de solution de45Ca par des poudres d'os, pauvres et riches en strontium, ainsi que celles de solution de85Sr par des poudres d'os, riches en strontium, ont été analysées. Des fonctions exponentielles et de puissance ont été établies. Les résultats indiquent que le strontium en solution atteint un équilibre d'échange dans l'os, à contenu élevé en strontium, en huit heures environ et que le calcium continue à rechercher un état d'équilibre. Il semble, en outre, que les réactions de diffusion et d'échange de surface de la phase solide hydratée soient les mécanismes majeurs observés pendant ces expériences.
    Abstract: Zusammenfassung Die Reaktionsfähigkeit von Rattenknochen mit niederem und hohem Strontiumgehalt wurdein vitro mit der Isotopenaustauschtechnik unter gut definierten Bedingungen untersucht. Kurven, welche die vom Knochenpulver mit niederem und hohem Strontiumgehalt aufgenommene45Ca-Menge, sowie jene von Knochenpulver mit ausschließlich hohem Strontiumgehalt aufgenommene85Sr-Menge wiedergaben, wurden ausgewertet. Die Gleichungen der Exponential- sowie der Potenzfunktionen wurden abgeleitet. Die Interpretation der Ergebnisse dieser Experimente ist, daß das Strontium der Lösung ein Austauschgleichgewicht mit Knochen mit hohem Strontiumgehalt nach einer Periode von etwa 8 Std erreicht, während Calcium fortfährt, sich einem Gleichgewichtsstadium zu nähern. Es wird weiterhin vermutet, daß Diffusion und Oberflächen-Austauschreaktionen der Hydratationsschicht der soliden Phase die vorherrschenden Vorgänge sind, die im Laufe dieser Experimente stattfinden.
    Notes: Abstract The reactivity of rat bone of low- or of high-strontium content was investigated by the technique of radioisotopic exchange under well-defined conditionsin vitro. Analyses of curves depicting the uptake from solution of45Ca by low- and by high-strontium bone powders, and of85Sr by high-strontium bone powder only, were performed. Both exponential and power function expressions were derived. The interpretation of results of these experiments is that strontium of solution reaches exchange-equilibrium with bone of high-strontium content over a period of about eight hours, but that calcium continues to approach a state of equilibrium. Further, it is suggested that diffusion and surface exchange reactions of the hydrated solid phase are the dominant processes operating during the periods of these experiments.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 5
    ISSN: 0002-9106
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The fate of heterologous, isologous and homologous ferritin-I125 injected into rat footpads was compared by determination of radioactivity in sera and organs, and by radioautography and electron microscopy. The clearance of heterologous ferritin-I125 from circulation was significantly faster than that of isologous or homologous ferritin-I125. This was supported by measurement of radioactivity in various organs, and by radioautography and electron microscopy of popliteal lymph nodes which reveled structural details of macrophages undergoing antigen uptake.These observations permit the following conclusions. (1) In most reticuloendothelial cells there is some nonspecific pinocytosis of antigen which is not related to immunogenicity. (2) The induction of massive immunologically specific pinocytosis by macrophages may be due to specific antigen recognition by receptors located at the cell surface. (3) Heterologous ferritin ingested by macrophages are mostly found in vacuoles or scattered in the ground cytoplasm. However, some appear in the nucleoplasm, usually in association with loose strands of chromatin materials. (4) Ferritin molecules are conspicuously absent from mitochondria, the rough-surfaced endoplasmic reticulum and Golgi apparatus. (5) The fiber-associated reticular cells of the primary nodule and germinal centers may correspond to “dendritic reticular cells” or “dendritic macrophages,” capable of long-term retention of antigens.
    Additional Material: 2 Tab.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...