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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 12 (1969), S. 218-226 
    ISSN: 1432-0533
    Keywords: Muscle ; Actin ; Z-Line ; Myofibril ; Loss of Myofilaments
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Verlust der I-Band-Myofilamente und des Materials im Z-Streifen werden bei drei verschiedenen pathologischen Zuständen beschrieben. dystrophischer Myotonie, subakuter spinaler Strangdegeneration und myatrophischer Lateralsklerose. Im Falle einer myatrophischen lateralsklerose wird auch eine Hypertrophie des Z-Streifens beschrieben. Es wird eine mögliche cyclische Alteration des Z-Streifens als Reaktion auf verschiedene, bisher unbekannte pathologische Reize und in Verbindung damit ein Verlust der Myofilamente des I-Bandes vermutet.
    Notes: Summary Loss of I-band myofilaments and Z-line material is described in three different pathological conditions; namely, dystrophia myotonica, sub-acute combined degeneration of the spinal cord and amyotrophic lateral sclerosis. In the case of amyotrophic lateral sclerosis hypertrophy of the Z-line is also described. A possible cyclical alteration in the Z-line in response to, so far unknown, pathological stimuli is suggested and in conjunction with this possible loss of I-band myofilaments.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 12 (1969), S. 183-188 
    ISSN: 1432-0533
    Keywords: Dystrophia myotonica ; Electron Microscopy ; Sarcolemmal Nuclei ; Myofibrillar Material
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung In fünf Fällen von Dystrophia myotonica zeigte die elektronenoptische Untersuchung von bioptisch entnommenem Material zentrale und subsarkolemmale Kerne, die komplexe vacuoläre Areale um myofibrilläres Material enthalten. Diese bisher nicht beobachtete Veränderung könnte durch Verlagerung von myofibrillärem Material in den Kern während seiner Wanderung in das Faserzentrum durch Invagination, aber nicht Durchbrechung der Kernmembran bedingt sein.
    Notes: Summary In five cases of dystrophia myotonica electron microscope preparations of muscle taken at biopsy showed both centrally placed and subsarcolemmal nuclei containing complex vacuolar areas enclosing myofibrillar material. It is suggested that this appearence, which has not been seen in any other condition, may be due to the forcing of myofibrillar material into the nucleus during its migration to the centre of the fibre invaginating but not breaching its membrane.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 4 (1965), S. 436-441 
    ISSN: 1432-0533
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Electron microscopy of motor end plates from cases of Guillain-Barré syndrome and myasthenia gravis showed that shrinkage of the terminal axonic expansions was accompanied by replacement of the expansion in its synaptic position by Schwann cell cytoplasm.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 5 (1965), S. 225-242 
    ISSN: 1432-0533
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung 1. In einer großen Serie von Muskelbiopsien von Fällen pseudohypertrophischer Muskeldystrophie zeigten vital gefärbte Präparate fast ausnahmslos Veränderungen an den motorischen Nervenendungen. 2. Die motorischen Endplatten zeigten entweder schwach gefärbte Anschwellung und Fusion der Endausbreitung mit Vereinfachung der Endverzweigungen oder Schrumpfung und dunkler Anfärbung der Endausbreitung, wodurch die Endplatten ein stumpfartiges Aussehen erhielten. Diese zweite Art der Veränderung zeigte sich vor allem an atropischen Muskelfasern. 3. Elektronmikroskopische Präparate lassen vermuten, daß die Vitalität der Neurone nicht vermindert ist und die beobachteten Veränderungen Sekundärerscheinungen einer primären Muskelfasererkrankung darstellen, die solchermaßen ein weiteres Beispiel für die Labilität der Struktur der motorischen Endplatten in bezug auf ihre Reaktionsfähigkeit bei Veränderungen ihrer Umgebung liefern.
    Notes: Summary 1. In a large series of muscle biopsies from cases of pseudohypertrophic muscular dystrophy vitally stained preparations almost invariably showed changes in the terminal motor innervation. 2. The motor end plates showed either pale staining swelling and fusion of the terminal expansions with some simplification of the terminal arborisation or shrinkage and dark staining of the terminal expansions giving the end plate a stumpy appearance. This second change was mainly seen on atrophic muscle fibres. 3. Electron microscopic preparations suggested that the vitality of the neurone was not diminished and the changes seen were secondary to primary disease of the muscle fibre thus providing yet another example of the lability of the structure of the motor end plate in response to changes in its environment.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 133 (1966), S. 0 
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 182 (1958), S. 1523-1523 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Meiotic division in the male sterile plants proceeded normally, but in the majority of anthers pollen development ceased at the tetrad stage, after which the young pollen grains degenerated. At flowering time the anthers were shrivelled (2 4 mm. long). In about 1 per cent of anthers occurring at ...
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Industrial & engineering chemistry 27 (1935), S. 1326-1332 
    ISSN: 1520-5045
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Scandinavian journal of immunology 6 (1977), S. 0 
    ISSN: 1365-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: In vitro exposure of mouse thymocytes to complexes of polyadenylic:polyuridylic acid (poly A:U) effected, within 6 h, the release of soluble factor(s) capable of nonspecifically enhancing IgM and IgG plaque-forming cells (PFCs) in in vitro primary and secondary spleen cell responses to burro erythrocytes. Poly A:U stimulation was, most likely, polyclonal, since production of soluble factor(s) occurred in the absence of antigen and in serum-free culture media. Poly A:U-induced soluble factor(s) were not capable of substituting for T cells but were dependent on T cells for the expression of PFC enhancement. These data support the hypothesis that the mechanism of poly A:U's adjuvant action is polyclonal stimulation of T cells, causing early induction and release of nonspecific, soluble PFC-enhancing factor(s).
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Naturwissenschaften 80 (1993), S. 176-178 
    ISSN: 1432-1904
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Digestive diseases and sciences 28 (1983), S. 1106-1115 
    ISSN: 1573-2568
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The timing of pyloric closure was studied at upper alimentary endoscopy in 20 subjects without antroduodenal pathology. Antral and duodenal contractions were recorded with ballon catheters and pyloric closure detected as a fall in impedance measured across two pairs of silver wire electrodes mounted around the shaft of the duodenal catheter 0.5 cm proximal to the balloon During 300 min of good quality recording, active pyloric closure was observed on 193 occasions and 69% of closures were associated with antral or duodenal contractions within 2 sec. In 55.5% of the 154 isolated duodenal contractions (no preceding antral contraction), the pylorus, which was closed before the contraction, remained closed; in 32% the pylorus, which was open, closed within 2 sec of the contraction, while in only 12.5% was the pylorus open throughout. These observations suggest that the pylorus is able to close in response to an isolated duodenal contraction and thus may act as a barrier to duodenogastric reflux when antroduodenal contractions are not linked.
    Type of Medium: Electronic Resource
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