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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 12 (1969), S. 183-188 
    ISSN: 1432-0533
    Keywords: Dystrophia myotonica ; Electron Microscopy ; Sarcolemmal Nuclei ; Myofibrillar Material
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung In fünf Fällen von Dystrophia myotonica zeigte die elektronenoptische Untersuchung von bioptisch entnommenem Material zentrale und subsarkolemmale Kerne, die komplexe vacuoläre Areale um myofibrilläres Material enthalten. Diese bisher nicht beobachtete Veränderung könnte durch Verlagerung von myofibrillärem Material in den Kern während seiner Wanderung in das Faserzentrum durch Invagination, aber nicht Durchbrechung der Kernmembran bedingt sein.
    Notes: Summary In five cases of dystrophia myotonica electron microscope preparations of muscle taken at biopsy showed both centrally placed and subsarcolemmal nuclei containing complex vacuolar areas enclosing myofibrillar material. It is suggested that this appearence, which has not been seen in any other condition, may be due to the forcing of myofibrillar material into the nucleus during its migration to the centre of the fibre invaginating but not breaching its membrane.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 4 (1965), S. 436-441 
    ISSN: 1432-0533
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Electron microscopy of motor end plates from cases of Guillain-Barré syndrome and myasthenia gravis showed that shrinkage of the terminal axonic expansions was accompanied by replacement of the expansion in its synaptic position by Schwann cell cytoplasm.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 5 (1965), S. 225-242 
    ISSN: 1432-0533
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung 1. In einer großen Serie von Muskelbiopsien von Fällen pseudohypertrophischer Muskeldystrophie zeigten vital gefärbte Präparate fast ausnahmslos Veränderungen an den motorischen Nervenendungen. 2. Die motorischen Endplatten zeigten entweder schwach gefärbte Anschwellung und Fusion der Endausbreitung mit Vereinfachung der Endverzweigungen oder Schrumpfung und dunkler Anfärbung der Endausbreitung, wodurch die Endplatten ein stumpfartiges Aussehen erhielten. Diese zweite Art der Veränderung zeigte sich vor allem an atropischen Muskelfasern. 3. Elektronmikroskopische Präparate lassen vermuten, daß die Vitalität der Neurone nicht vermindert ist und die beobachteten Veränderungen Sekundärerscheinungen einer primären Muskelfasererkrankung darstellen, die solchermaßen ein weiteres Beispiel für die Labilität der Struktur der motorischen Endplatten in bezug auf ihre Reaktionsfähigkeit bei Veränderungen ihrer Umgebung liefern.
    Notes: Summary 1. In a large series of muscle biopsies from cases of pseudohypertrophic muscular dystrophy vitally stained preparations almost invariably showed changes in the terminal motor innervation. 2. The motor end plates showed either pale staining swelling and fusion of the terminal expansions with some simplification of the terminal arborisation or shrinkage and dark staining of the terminal expansions giving the end plate a stumpy appearance. This second change was mainly seen on atrophic muscle fibres. 3. Electron microscopic preparations suggested that the vitality of the neurone was not diminished and the changes seen were secondary to primary disease of the muscle fibre thus providing yet another example of the lability of the structure of the motor end plate in response to changes in its environment.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 8 (1967), S. 104-107 
    ISSN: 1432-0533
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Es wird über ein Medulloblastom bei zwei Brüdern berichtet. Die Diagnose wurde histologisch bestätigt, und zwar bei einem Bruder bei der Autopsie, beim anderen in einer chirurgischen Biopsie.
    Notes: Summary The case of a medulloblastoma occurring in each of two brothers is reported. The diagnosis was confirmed on histological examinations, at autopsy on one and on an operation specimen from the other.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 184 (1959), S. 1500-1500 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] An abnormality in the ultra-structure of the synaptic region in such end-plates would, however, be more acceptable as the morphological component of this reversible disorder of transmission. We have, therefore, in our present study of the ultra-structure of the human end-plate in myasthenia and ...
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 135 (1966), S. 0 
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 226 (1970), S. 1061-1062 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Thus while all the muscle fibres in the enlarged pool served by a neurone previously maintaining type 1 fibres would now be of type 1, only a portion of the enlarged pool served by a neurone previously innervating exclusively type 2 fibres would be of type 2 (Figs. 1-3). We have recently been able ...
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Journal of neurology 179 (1959), S. 423-430 
    ISSN: 1432-1459
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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