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pH dependence of phosphate reabsorption in the proximal tubule of rat kidney (1975)

Baumann, K. ; Rumrich, G. ; Papavassiliou, F. ; [et al.]

Springer

Pflügers Archiv 360 (1975), S. 183-187

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ISSN: 1432-2013

Keywords: Renal tubule ; Phosphate transport ; pH dependence ; Micropuncture ; Microperfusion

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Summary Early loops of the proximal convoluted tubule of parathyroidectomized rats (PTX-rats) were microperfused with a phosphate (4 mM) containing perfusate. With a perfusion solution of pH around 7.45 as estimated as anion deficit theP i reabsorption was two times greater than with a perfusion solution of pH around 6.85. TheP i reabsorption is reduced in PTX-rats made chronic alkalotic (PTX-cA-rats) but the same pH dependence ofP i reabsorption was found. The data indicate that the divalent phosphate is preferentially reabsorbed.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00580540

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