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  • 1
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of agricultural and food chemistry 26 (1978), S. 812-816 
    ISSN: 1520-5118
    Source: ACS Legacy Archives
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Cats (0.5-1.6 kg) were anaesthetised with sodium pentobar-bital (30 mg per kg i.p.) and papillary muscles (mean cross-sectional area 0.62 ± 0.05 mm2, n = 17) were dissected from the right ventricles. The preparations were attached to a platinum stimulating electrode and mounted individually ...
    Type of Medium: Electronic Resource
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  • 3
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    Unknown
    Wiesbaden : Periodicals Archive Online (PAO)
    Geographische Zeitschrift. 64:4 (1976) 307 
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Computing 20 (1978), S. 189-205 
    ISSN: 1436-5057
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Description / Table of Contents: Zusammenfassung Eines der am besten beschriebenen Modelle kombinatorischer Optimierung ist das Scheduling Problem, bei dem eine endliche Anzahl von Tätigkeiten auf einer festen Anzahl von Maschinen so ausgeführt werden muß, daß eine gegebene Zielfunktion minimiert wird. Jede Tätigkeit benötigt charakteristische Daten wie Bearbeitungszeit, Fertigsteillungstermin, Strafkosten und technologische Nachfolgebeziehungen. Ein algebraischer Ansatz für die Zielfunktion führt zu einem allgemeinen Problem, das alle in der Literatur bekannten klassischen Fälle von Summen und Maximum Zielfunktionen einschließt. Durch die Lösung eines algebraischen Transportproblems wird eine untere Schranke für den Zielfunktionswert bestimmt. Um eine Optimallösung zu erhalten, verwenden wir ein Branch and Bound Verfahren. Weiterhin betrachten wir das allgemeine Job Shop Scheduling Problem mit algebraischer Zielfunktion.
    Notes: Abstract One of the well-studied models of combinatorial optimization is the scheduling problem dealing with a finite set of tasks, which have to be executed on a fixed number of machines so that a given objective is minimized. Each task requires a set of characteristic data like operating time, due date, penalty cost and technological requirements. An algebraic approach to the objective leads to a general problem which includes all classical cases of sum and bottleneck objectives known in literature. By solving an algebraic transportation problem a lower bound for the objective value can be determined. To obtain an optimal solution we employ a branch and bound procedure. Furthermore we consider the general job shop scheduling problem with algebraic objective function.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Neophilologus 62 (1978), S. 513-526 
    ISSN: 1572-8668
    Source: Springer Online Journal Archives 1860-2000
    Topics: Linguistics and Literary Studies
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Research in experimental medicine 168 (1976), S. 57-64 
    ISSN: 1433-8580
    Keywords: Liver perfusion ; hypothermia ; Q10 values of various metabolic processes ; activation energies ; Leberperfusion ; Hypothermie ; Q10-Werte verschiedener Stoffwechselprozesse ; Aktivierungsenergien
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Experimente mit perfundierten Rattenlebern haben gezeigt, daß verschiedene Stoffwechselprozesse (Glycolyse, Fructolyse, Glycogenolyse, Ketogenese, CO2-Produktion, oxydative Pyruvatdecarboxylierung, Gluconeogenese) eine unterschiedliche Temperaturabhängigkeit haben. Diese Temperaturabhängigkeit kann sich außerdem bei Übergang in einen anderen Temperaturbereich ändern. Die Q10-Werte lagen zwischen 1, 7 und 25 und entsprechen in erster Näherung Aktivierungsenergien von 38 bis 216 kJ/Mol.
    Notes: Summary The temperature dependence of various metabolic processes (glycolysis, fructolysis, glycogenolysis, ketogenesis, CO2-production, oxidative decarboxylation of pyruvate and gluconeogenesis) was studied in perfused rat livers. The processes measured differed with respect to their temperature dependence. Moreover, the sensitivity towards changes in temperature differed depending on the temperature range. Q10 values were found between 1, 7 and 25 corresponding to values for activation energies between 38 and 216 kJoule/Mol.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Research in experimental medicine 168 (1976), S. 157-163 
    ISSN: 1433-8580
    Keywords: Maltose ; perfused rat liver ; isolated hepatocytes ; glucose production
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The conversion of14C-maltose into glucose, lactate and14 CO2 was studied in perfused livers from fed and fasted rats and in isolated hepatocytes. Maximal glucose production was 30 mM x g−1 x h−1; half-maximal rates were found with 3 mM maltose. About 0.01 % of the radioactivity infused was recovered as14CO2. The addition of maltose had no effect on rates of oxygen consumption, lactate production or ketogenesis. The data suggest that maltose did not serve as a major substrate for biosynthetic or energy producing processes under the conditions of the perfused rat liver.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1432-2323
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé Trois techniques d'examen radioisotopique sont utiles au diagnostic et au traitement des ischémies myocardiques. 201-Thallium est un analogue du potassium; après administration intraveineuse, sa distribution dans le tissu myocardique est proportionnelle au débit sanguin régional. Les mesures faites avec 201-Thallium au repos et pendant l'effort identifient les zones d'ischémie et de fibröse myocardique et permettent une évaluation fonctionnelle des débits sanguins régionaux. Avec cet isotope, on a pu démontrer, après pontage coronaire, des améliorations de l'irrigation myocardique; la méthode peut donc être utile dans l'évaluation postopératoire. Le 99m-Technetium pyrophosphate se localise dans le tissu myocardique infarci et est donc particulièrement intéressant pour le diagnostic de l'infarctus postopératoire. Cette méthode permet de démontrer les infarctus myocardiques aigus lorsque le diagnostic ne peut être confirmé par la clinique ou par l'électrocardiogramme. L'angiographie par radioisotope est la troisième technique, très prometteuse pour la surveillance des ischémies myocardiques. L'injection d'un embol de traceur et l'enregistrement rapide de l'activité précordiale par une gamma caméra computérisée permettent de mesurer les temps de transit et les volumes moyens des diverses chambres cardiaques, le débit cardiaque, les volumes ventriculaires, et la fraction d'éjection. La méthode donne des mesures en série de la fonction cardiaque et permet d'évaluer la réponse cardiaque à l'effort. Les malades en ischémie myocardique présentent, en réponse à l'accroissement du travail cardiaque, une dilatation aiguë du ventricule gauche, et l'importance de cette dilatation parait bien être proportionnelle à l'étendue de la zone ischémiée. Une revascularisation myocardique réussie supprime cette réponse anormale à l'effort et l'amélioration de la fonction ventriculaire gauche peut être mise en évidence par des épreuves d'effort après pontage coronaire.
    Notes: Abstract Three noninvasive radionuclide techniques are of value in diagnosis and management of patients with myocardial ischemia.201Thallium is an analogue of potassium that is distributed in myocardial tissue in proportion to regional blood flow following intravenous administration. Studies obtained using this agent during rest and exercise identify regions of myocardial fibrosis and ischemia and provide a functional assessment of regional blood flow. Improvement in the distribution of regional myocardial perfusion has been documented following coronary artery bypass grafting, and the procedure may have practical importance in the postoperative assessment of patients.99mTechnetium pyrophosphate is a radiopharmaceutical that localizes in acutely infarcted myocardial tissue and is of particular benefit in the diagnosis of postoperative myocardial infarction. Documentation of acute myocardial infarction by this method is indicated in patients in whom the diagnosis cannot be confirmed by electrocardiograms or other clinical modalities. Radionuclide angiocardiography is a third radionuclide technique that holds great promise in the management of patients with myocardial ischemia. A single bolus injection of tracer with rapid recording of precordial counts using a computerized gamma camera provides measurement of individual chamber transit times and mean volumes, cardiac output, and ventricular volumes and ejection fraction. The study provides serial measurements of cardiac function and permits evaluation of the cardiac response to acute exercise stress. Patients with myocardial ischemia acutely dilate the left ventricle in response to increased cardiac work load, and the magnitude of dilatation appears to be related to the magnitude of ischemia. Successful myocardial revascularization reverses the abnormal response to exercise, and greatly improved left ventricular function can be documented during exercise following coronary artery bypass grafting.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 34 (1978), S. 504-505 
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Theophylline (0.01–10.0 mM) did not incease but rather decreased adenylate cyclase activity (AC) of guineapig auricles. Isoprenaline (1–100 μM) and sodium fluoride (0.3–10.0 mM)stimulated AC in aconcentration-dependent manner.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Research in experimental medicine 173 (1978), S. 285-292 
    ISSN: 1433-8580
    Keywords: Urate metabolism ; Restraint stress ulcers ; Allopurinol ; Doseresponse studies ; Stress hyperuricemia ; Gastric acid ; Mucosal blood flow
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Stress and allopurinol (ALL) were investigated in rats with regard to their influence on serum uric acid and glucose concentration, gastric secretion, microcirculation (MBF) and stress ulcer index. There is a noncompetitive type of interaction between severe stress and ALL-mediated xanthine oxydase inhibition (= per cent fall in serum uric acid) as compared with control conditions (= mild stress).V max is different (84.6 ± 1.9 and 92.3 ± 2.26;P 〈 0.05), but notK m (0.39 ± 0.09 and 0.68 ± 0.08 mg/kg/h ALL). Serum uric acid is higher in rats with draining gastric fistula than those with closed fistula suggesting that already mild stress is associated with an increase in uricemia in this species. ALL does not significantly alter gastric acid and uric acid secretion but improves markedly gastric ulcer index during mild and severe stress. Since MBF is significantly elevated by ALL during the latter circumstances, a dissociation between MBF and acid secretion is one feature of ALL actions and might become a primary aim in treatment of this disorder.
    Type of Medium: Electronic Resource
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