ISSN:
1573-4927
Keywords:
adenylate kinase isozymes
;
phosphopyruvate hydratase
;
6-phosphogluconate dehydrogenase
;
phosphoglucomutase-1
;
chromosome 1
;
man-rodent somatic cell hybrids
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Chemistry and Pharmacology
Notes:
Abstract The expression of the adenylate kinase isozymes and of phosphopyruvate hydratase was studied in man-mouse and man-hamster hybrid clones. Concordant segregation of the loci coding for AK-2 and PPH was observed in 54 of 55 primary hybrid clones, and these loci were demonstrated to be synthetic with the loci specifying PGM-1 and PGD. The pattern of expression of the four enzymes in discordant clones suggests the gene order 1pter-(PGD,PPH)-AK-2-PGM-1-centromere. In addition, AK-1 was found to be expressed independently of AK-2.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00484869
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