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  • 1995-1999  (3)
  • 1980-1984  (2)
  • 1965-1969
  • 1900-1904
  • 1997  (3)
  • 1984  (1)
  • 1983  (1)
Material
Years
  • 1995-1999  (3)
  • 1980-1984  (2)
  • 1965-1969
  • 1900-1904
Year
  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 104 (1997), S. 0 
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, U.K. and Cambridge, USA : Blackwell Science Ltd
    Plant pathology 46 (1997), S. 0 
    ISSN: 1365-3059
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Samples of maize seed were obtained from countries in Central America, Africa and Asia and assessed for fungal infection. Fusarium spp. were the largest single group of fungi present, and from these Fusarium moniliforme was the species most frequently isolated. Other fungi, including Stenocarpella (Diplodia) maydis, S. macrospora and Acremonium strictum, were also present in significant numbers. Isolates of F. moniliforme were characterized for mating populations, using RAPDs, and a number of isolates, taken at random from those assigned to specific mating groups, were also confirmed by crossing. Isolates were also characterized for fusaric acid production and significant differences in fusaric acid production were detected between isolates from different countries and regions within countries. A detailed analysis of isolates from one country, Kenya, was undertaken. The importance of the pathogens is discussed in relation to human, animal and seed health and quarantine regulations, and plant breeding objectives.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford BSL : Blackwell Science
    Alimentary pharmacology & therapeutics 11 (1997), S. 0 
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease characterized by a progressive obliterating fibrosis of the intrahepatic and extrahepatic bile ducts. The pathogenesis of PSC is poorly understood but it is thought to be an immune-mediated disease. The optimal therapy which successfully improves symptoms, delays progression towards liver failure and transplantation and prevents the onset of cholangiocarcinoma remains elusive. Although current treatments are used to manage cholestasis and its consequences and some of the more general complications of the disease, none of the current therapeutic agents have been shown to retard and reverse the rate of disease progression. The role of cupruretics, corticosteroids, methotrexate, anti-fibrogenic agents and ursodeoxycholic acid in the treatment of PSC is reviewed. Orthotopic liver transplantation remains the only therapeutic option for advanced PSC but the timing of transplantation remains controversial and the possibility of recurrence of the disease in the graft is increasingly recognised. It is likely that greater insight into the pathogenetic mechanisms involved in PSC will allow therapy to be targetted more specifically at the biliary epithelium.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Digestive diseases and sciences 28 (1983), S. 321-327 
    ISSN: 1573-2568
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The absorption of nonheme59ferric chloride from a test meal was measured, using a whole-body counter, in 34 alcoholics with liver disease of varying severity, 30 of whom had normal hemoglobin values and four of whom were anemic. The results were compared with those obtained in five patients with iron-deficient anemia and nine healthy control subjects. There were no significant differences in mean percentage iron absorption (±sem) in the nonanemic alcoholic patients with fatty liver (14.6±3.7), alcoholic hepatitis (18.6±5.7), or cirrhosis (21.1±3.5) when compared with control subjects (22.0±2.5). Significantly increased mean percentage iron absorptions were seen, however, in the patients with iron-deficient anemia (64.8±5.6;P〈0.0001) and the alcoholics with anemia (60.7±7.8;P〈0.0001). There was an inverse relationship between iron absorption and serum ferritin concentration in the nonanemic alcoholics (r=−0.37;P〈0.025) but no correlation between iron absorption and liver iron concentration. The addition of absolute alcohol (0.5 g/kg body weight) to the test meal resulted in an increase in mean percentage iron absorption in eight control subjects (21.6±1.6 to 29.0±6.1) and in ten nonanemic alcoholics (15.8±3.2 to 20.0±3.8), although these differences did not achieve significance. Similarly when intravenous alcohol was given to four control subjects at the time of the test meal, iron absorption increased in all four so that the mean percentage iron absorption increased, although not significantly, from 17.6±2.7 to 39.3±9.5. Iron absorption in alcoholics does not differ significantly from normal. While the increased liver iron concentrations seen in approximately one third of alcoholics cannot be attributed to an increase in iron absorption as a result of chronic alcohol ingestion, further studies are needed to elucidate the acute effects of alcohol on iron absorption.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    American Journal of Anatomy 171 (1984), S. 441-456 
    ISSN: 0002-9106
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Isthmic and ampullary oviductal epithelia sampled from Merino ewes at days -1, 1, 3, and 10 of the estrous cycle (estrus = day 0) were studied by scanning and transmission electron microscopy after fixation by vascular perfusion. Secretory cells, ciliated cells, and lymphocytelike basal cells were observed in both isthmic and ampullary epithelium at all stages of the estrous cycle studied and their ultrastructural features were analyzed. Synthesis of lamellated secretory granules occurred in the ampullary secretory cells during the follicular and early luteal phases, and their contents were released by exocytosis into the oviductal lumen during the luteal phase. Granule release was associated with nucleated apical protrusion of these cells into the oviductal lumen. No such secretory activity was displayed by isthmic secretory cells even though a few cells contained nonlamellated granules. Apocrine release of apical vesicles and accompanying cytoplasmic material from apical protrusions of ciliated cells occurred in the isthmus around estrus but not in the ampulla. This unexpected feature has not previously been reported in any other mammal. Dendritic basal cells were distinguished in the lower part of the epithelium by their heterochromatic nuclei, electron-lucent cytoplasm, and lack of attachment zones. No migration of basal cells was observed, and their ultrastructural features were similar in the ampulla and isthmus and at all stages of the estrous cycle examined. The function of these lymphocytelike cells in the epithelium is uncertain, but the presence of phagocytic bodies and lysosomes in 20% of them may indicate a phagocytic role.
    Additional Material: 18 Ill.
    Type of Medium: Electronic Resource
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