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  • 1980-1984  (3)
  • 1965-1969
  • 1950-1954
  • 1983  (3)
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  • 1980-1984  (3)
  • 1965-1969
  • 1950-1954
Year
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  • 1
    Electronic Resource
    Electronic Resource
    VERAPAMIL-INDUCED CONTRACTURE IN AN EXCISED, BLOOD-PERFUSED SKELETAL MUSCLE PREPARATION FROM THE DOG (1983)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical and experimental pharmacology and physiology 10 (1983), S. 0 
    Details
    ISSN: 1440-1681
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: 1. The ability of verapamil to induce a contractile response in skeletal muscle was investigated using the canine isolated, blood-perfused diaphragm preparation.2. Verapamil-induced contracture was characterized by a biphasic increase in muscle tension consisting of an initial phasic and subsequent tonic contracture.3. The second tonic component of the verapamil-induced contracture was inhibited by procaine, but procaine had no effect on the initial phasic contracture.4. Verapamil potentiated both KCl- and caffeine-induced contractures during the second tonic stage. This action might be explained by enhancement by the drug of availability, or by an increased sensitivity of the contractile machinery to calcium liberated by membrane depolarization or by the calcium-induced calcium release mechanism.5. The second tonic component of verapamil-induced contracture was much less than the initial phasic component. It seems, therefore, that the calcium release induced by the procaine-resistant process is the principal action of verapamil in inducing contracture in skeletal muscle.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1440-1681.1983.tb00218.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Aortic fibrous components in exercised rats (1983)
    Springer
    Cellular and molecular life sciences 39 (1983), S. 371-372 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary In exercised female rats, the elastin content of the thoracic and abdominal aorta decreased by 4–8% (p〈0.05). The collagen content in the thoracic aorta, was unchanged but in the abdominal aorta was reduced by 5.2% (p〈0.05). These results are discussed in connection with physical training.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01963128
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Elution characteristics of some solutes used to measure the column void time on reversed-phase stationary phases in micro-HPLC (1983)
    Springer
    Chromatographia 17 (1983), S. 341-344 
    Details
    ISSN: 1612-1112
    Keywords: Column void time ; Reversed-phase HPLC ; Vacancy peak ; IR direct monitoring
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Summary The elution characteristics of some solutes commonly used to measure column void time on three reversedphase stationary phases in micro-HPLC are described. The elution characteristics of sodium nitrie, sodium nitrate, deuterium oxide, acetone and N,N-dimethylformamide were determined by using styrene-divinylbenzene copolymer, octylsilica and octadecylsilica columns with aqueous methanol and/or acetonitrile eluents. The results indicate that sodium nitrite and sodium nitrate are suitable solutes in measuring column void time, and that the elution behavior of deuterium oxide is almost similar to that of both sodium salts but it appears as two peaks on a C-18 column. One of the two peaks is confirmed as “vacancy” by the use of the micro-HPLC/IR direct monitoring system.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02270671
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    Paper (German National Licenses)
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