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  • 1985-1989  (6)
  • 1880-1889
  • 1985  (6)
Source
Material
Years
  • 1985-1989  (6)
  • 1880-1889
Year
  • 1
    Electronic Resource
    Electronic Resource
    NMR study of dilute solutions of main-chain nematic polyesters in p-azoxyanisole (1985)
    s.l. : American Chemical Society
    Macromolecules 18 (1985), S. 2620-2623 
    Details
    ISSN: 1520-5835
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ma00154a044
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Magnetic susceptibility as a probe of the solid-discotic phase transition in binuclear copper(II) n-alkanoates (1985)
    s.l. : American Chemical Society
    Inorganic chemistry 24 (1985), S. 4452-4454 
    Details
    ISSN: 1520-510X
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ic00220a004
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    The modulation of peritoneal macrophage chemiluminescence by acute pleural inflammation, prostanoids and cyclo/lipoxygenase inhibitors (1985)
    Springer
    Inflammation research 17 (1985), S. 184-191 
    Details
    ISSN: 1420-908X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The chemiluminescent (CL) response of peritoneal macrophages was suppressed by induction 4 h earlier of an inflammatory reaction in the pleural cavity which was negated by prior administration of indomethacin, ketoprofen and BW 755C. These changes were accompanied by a concomitant rise in peritoneal PGI2 levels which was abolished by drug pretreatment.In vitro treatment of normal peritoneal macrophages with PGI2 inhibited their subsequent CL response. Indomethacin and ketoprofen produced elevated CL of macrophages obtained from untreated controlsin vitro which was blocked by the lipoxygenase inhibitor NDGA. BW 755C and NDGAin vitro strongly inhibited macrophage CL and partially inhibited CL in a cell-free system. Use of these drugsin vivo demonstrated that indomethacin and ketoprofen augmented the CL response of peritoneal macrophages while BW 755C had no effect. These results suggest the inflammatory processper se can modulate the functions of macrophages in parts of the body remote from the inflammatory site. Moreover this modulation may be under the control of the prostanoid system.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01966590
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    In vitro andin vivo effects of gold salts on chemotaxis and random migration of rat polymorphonuclear leucocytes (1985)
    Springer
    Inflammation research 16 (1985), S. 363-368 
    Details
    ISSN: 1420-908X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The effect produced by three gold salts (sodium aurothiomalate, allochrysine, auranofin) on chemotaxis and random migration of rat polymorphonuclear leucocytes (PMN) was investigated under various experimental conditions. The drug activity was examined after incubationin vitro or after administrationin vivo. PMNs were recruited after the induction of two acute inflammatory reactions (pleurisies induced by isologous serum or a suspension of calcium pyrophosphate (CaPP) crystals). The three gold salts administeredin vivo andin vitro inhibited the chemotactic responses of the two cell types. This action was dose-dependent. Auranofin was the most effective substance while sodium aurothiomalate was the least. The random migration was not always significantly depressed especially for CaPP-elicited cells. Reduction in neutrophil chemotaxis might be an important additional mechanism in the action of gold salts and their activity on inflammatory PMNs recruited at inflammatory foci might be beneficial in the treatment in rheumatic diseases in which PMN migration would be implicated.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01982874
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Effect of acute nonimmune inflammation on locomotion of exudate and blood rabbit neutrophils (1985)
    Springer
    Inflammation 9 (1985), S. 389-394 
    Details
    ISSN: 1573-2576
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The random and directed locomotion of rabbit polymorphonuclear neutrophils (PMNs) were investigated in vitro by the agarose technique. PMNs were either recruited in serum-elicited pleural exudates or isolated from blood collected before or after pleurisy development. Directed PMN migration was assessed in the presence ofN-formyl-methionyl-leucyl-phenylalanine (FMLP), isologous rabbit serum (IRS) or cell-free exudates as chemotactic stimuli. Neutrophils collected from blood before pleurisy induction or 4 h afterwards displayed similar random migration, and similar migration oriented by FMLP, IRS, or cell-free exudates. However, both random and FMLP-induced migration were greater for exudate than blood PMNs. In the presence of IRS or cell-free exudate as chemoattractants, exudate and blood PMNs migrated over similar distances. These results suggest that exudation does not deactivate elicited PMNs but alters their locomotion responses according to the stimulus applied.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00916338
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Bradykinin levels in inflammatory exudates (1985)
    Springer
    Inflammation 9 (1985), S. 419-424 
    Details
    ISSN: 1573-2576
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract An enzyme immunoassay was used to measure the levels of bradykinin (BK)-like immunoreactivity in inflammatory exudates provoked by calcium pyrophosphate (CaPP) or carrageenin. BK-like immunoreactivity increased from 4 to 18 ng/ml in exudates provoked by CaPP and collected from 30 min to 3 h after induction of pleurisy. BK levels decreased progressively (from 16 to 3 ng/ml) in the samples collected at 4 and 6 h. BK levels did not increase in exudates provoked by carrageenin. Control samples of exudates provoked by CaPP but not treated with peptidase inhibitors [orthophenanthroline (OPH) or a mixture of EDTA-captopril-thioglycolic acid (ECT)] as well as samples containing one or the other peptidase inhibitors dissolved in saline, were also negative. The present results indicate that an increased production of kinins is detectable only in exudates induced by CaPP and not in those provoked by carrageenin. Our data also suggest that the kinins are rapidly metabolized, both in vitro (in the exudate sample) and in vivo (in the rat pleural cavity).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00916341
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    Paper (German National Licenses)
    Fulltext
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