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  • 1
    Electronic Resource
    Electronic Resource
    Review article: treatment of Helicobacter pylori infection with ranitidine bismuth citrate- or proton pump inhibitor-based triple therapies (2000)
    Oxford UK : Blackwell Science Ltd
    Alimentary pharmacology & therapeutics 14 (2000), S. 0 
    Details
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Triple therapy, combining a proton pump inhibitor with clarithromycin (C) and either amoxycillin (A) or a nitro-imidazole (I) is the standard in Helicobacter pylori eradication therapy. Recently, triple therapies based on ranitidine bismuth citrate (RBC) have emerged as an alternative. This review examines the current literature for studies directly comparing proton pump inhibitor- with RBC-based triple therapies. Seventeen studies were identified, of which three have been published as a full paper.Eradication rates in an intention-to-treat analysis ranged from 51 to 98%. No large difference in cure rates between the different regimens was demonstrated, although the RBC-I-C combination was somewhat superior. No definite conclusions could be made about the impact of metronidazole or clarithromycin resistance since only three studies performed a formal resistance analysis. No serious side-effects were reported, and dropout rates were equal for the two regimens.Both RBC- and proton pump inhibitor-based triple therapies are highly effective. If one prefers a imidazole/clarithromycin combination the evidence presented here suggests that RBC should be used instead of a proton pump inhibitor. Larger studies comparing both forms of triple therapy, using proper resistance analysis, are needed before final conclusions can be reached regarding efficacy in the setting of bacterial resistance.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2036.2000.00798.x
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  • 2
    Electronic Resource
    Electronic Resource
    Gingival health and frequency of tooth brushing in the beagle dog model (1986)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of clinical periodontology 13 (1986), S. 0 
    Details
    ISSN: 1600-051X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract The aim of this experiment was to study clinical parameters when 3 different frequencies of plaque removal were applied to healthy gingivae in the beagle dog model. The maxillary first, second and third premolars of 12 beagle dogs, at the start of the experiment 2 years of age, were, after a thorough cleaning, submitted to daily plaque removal during a pre-experimental period of 8 weeks. At the start of the experiment, the dogs were distributed into 3 groups of 4 dogs each: one group was brushed 7 times a week, a second group was brushed 3 times a week and another group was brushed only once a week. Brushing was executed over a period of 24 weeks, on the right sides of the upper jaws. The left upper jaws served as controls. At regular intervals, the plaque index, the gingival index and probing depths were assessed. A “brushing effect” was calculated for each dog, to include information on all within-dog and between dog variations. Comparison of brushing effects revealed that in this experimental model, plaque removal with a frequency of 3 times a week was sufficient to preserve gingival health, whereas tooth brushing once a week resulted in gingival inflammation. Therefore it can be concluded that 3 times a week is the critical brushing frequency in the beagle dog model with healthy gingiva at baseline.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-051X.1986.tb01451.x
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  • 3
    Electronic Resource
    Electronic Resource
    Artificial periodontal defects and frequency of tooth brushing in beagle dogs (1986)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of clinical periodontology 13 (1986), S. 0 
    Details
    ISSN: 1600-051X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract This investigation was designed to determine the influence of different frequencies of tooth brushing on artificial periodontal defects in the beagle dog shortly after creation.In 12 beagle dogs, periodontal defects were created using elastic bands placed in the sulci below the gingival margin after having cut the dento-gingival fibres to the level of the alveolar bone. This active phase of creating defects lasted for 6 weeks. 6 premolars in the lower jaw were used (2P2, 3P3, 4P4). After removal of the elastic bands, the 12 dogs were distributed into 3 groups of 4 dogs each. Each group was brushed with a certain frequency, i.e., 7 times, 3 times or once a week. Plaque index, gingival index and probing depth, using a constant force probe, were assessed interproximally. The experiment lasted for 24 weeks.For hypothesis testing, a brushing effect was calculated for each dog. Furthermore, an analysis was performed based on the absolute scores at week 24. From the statistical analysis, it was concluded that in artificially-induced periodontal defects in beagle dogs immediately after creation, brushing 7 times a week is superior to brushing 3 times a week to establish and maintain gingival health.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-051X.1986.tb01450.x
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  • 4
    Electronic Resource
    Electronic Resource
    Artificial periodontal defects and frequency of tooth brushing in beagle dogs (1986)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of clinical periodontology 13 (1986), S. 0 
    Details
    ISSN: 1600-051X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract This investigation was designed to determine the influence of different frequencies of tooth brushing on artificial periodontal defects in the beagle dog after a period of healing.In 12 beagle dogs, periodontal defects were created using elastic bands placed in the sulci below the gingival margin after having cut the dento-gingival fibres to the level of the alveolar bone crest. This active phase of creating defects lasted for 6 weeks. After removal of the elastic bands, the created defects were left undisturbed during the remainder of the pre-experimental period (12 weeks). 6 premolars in the lower jaw were used (2P2, 3P3, 4P4).After the pre-experimental period, the 12 dogs were distributed into 3 groups of 4 dogs each. Each group was brushed with a certain frequency, i.e., 7 times, 3 times or once a week.Registrations of plaque index, gingival index and probing depth using a constant force probe were carried out on approximal surfaces. The experiment lasted for 24 weeks. A brushing effect was calculated for each dog to include information on all within-dog and between-dog variations. It was shown in relation to artificially-induced periodontal defects in beagle dogs that after a period of healing, brushing 7 times a week is superior to brushing 3 times a week in establishing and maintaining gingival health.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-051X.1986.tb01457.x
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  • 5
    Electronic Resource
    Electronic Resource
    Experimental gingivitis and frequency of tooth brushing in the beagle dog model (1986)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of clinical periodontology 13 (1986), S. 0 
    Details
    ISSN: 1600-051X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract The aim of this experiment was to study clinical parameters when 3 different frequencies of tooth brushing were applied to sites of experimental gingivitis in beagle dogs. 12 beagle dogs, at the start of the experiment 2 years of age, were used. After a thorough cleaning, the maxillary left and right first, second and third premolars were brushed daily for a period of 8 weeks. Subsequently, for 4 weeks, all brushing was omitted in order to establish an experimental gingivitis. After this pre-experimental period, the dogs were distributed into 3 groups of 4 dogs each: one group was brushed 7 times a week, a second was brushed 3 times a week and the third group was brushed only once a week. Brushing was carried out for 24 weeks, only on the right sides of the upper jaws, the left upper jaws serving as controls. At regular intervals, plaque index, gingival index and probing depths were assessed. A brushing effect was calculated for each dog, to include information on all within-dog and between-dog variations.The present study demonstrated that only by brushing every day can clinically healthy gingivae be obtained in the beagle dog model with experimental gingivitis at baseline. The state of gingival health at baseline may be used to determine the frequency of brushing necessary to create or maintain healthy gingivae.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-051X.1986.tb01458.x
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  • 6
    Electronic Resource
    Electronic Resource
    On a possible substitution of p-xylene by toluene in p-xylene crystals. The crystal structure of p-xylene, C8H10, at 180 K (1986)
    Copenhagen : International Union of Crystallography (IUCr)
    Acta crystallographica 42 (1986), S. 491-497 
    Details
    ISSN: 1600-5740
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0108768186097847
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  • 7
    Electronic Resource
    Electronic Resource
    Structure of (+)-5,6,7,8-tetradehydro-3-methoxy-17-methylmorphinan-4-ol hemihydrate, a potential morphinadien for Diels–Alder reactions (1986)
    Oxford [u.a.] : International Union of Crystallography (IUCr)
    Acta crystallographica 42 (1986), S. 103-105 
    Details
    ISSN: 1600-5759
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0108270186097159
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  • 8
    Electronic Resource
    Electronic Resource
    Strategies for structure solution and refinement of small organic molecules from electron diffraction data and limitations of the simulation approach (2000)
    [S.l.] : International Union of Crystallography (IUCr)
    Acta crystallographica 56 (2000), S. 436-450 
    Details
    ISSN: 1600-5724
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Notes: In recent years, a series of non-linear optically active bis(benzylidene) ketones have been synthesized and investigated by electron crystallography. In most cases, structure refinement was possible by combining electron diffraction analysis and quantum-mechanical calculations with maximum-entropy methods. However, when the torsional angles between the phenyl rings and the C=C double bonds are strongly affected by the crystal field, this method fails because packing-energy calculations are not sufficiently sensitive. This problem can be solved by refining the approximate model with SHELXL, if the data set is sufficiently accurate and the model close to the correct structure. Here it is shown that a considerably superior data set can be obtained at 300 kV with on-line data acquisition.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0108767300006668
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    Paper (German National Licenses)
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  • 9
    Electronic Resource
    Electronic Resource
    Bicadinane, a C 30 pentacyclic isoprenoid hydrocarbon found in crude oil (1986)
    [s.l.] : Nature Publishing Group
    Nature 319 (1986), S. 316-318 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Fig. 1 A, Mass spectrum of compound T from crude oil from well W. Prabumulih-3; B, 500MHz ?-??? spectrum of compound T. Isopropyl group a, 6CH3 = 0.68 and 0.83, Stert ? = 1.96, / = 6.9 Hz. Isopropyl group 6, CH3 = 0.72 and 0.84, Stert H = 2.10, / = 6.9 Hz. Four high-field protons c, d = 0.3-0.5, ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/319316a0
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  • 10
    Electronic Resource
    Electronic Resource
    Structure of 4-tert-butyl-2,6-dimethylacetophenone–iron(III) chloride (1/1) (1986)
    Oxford [u.a.] : International Union of Crystallography (IUCr)
    Acta crystallographica 42 (1986), S. 41-43 
    Details
    ISSN: 1600-5759
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S010827018609738X
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    Paper (German National Licenses)
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