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  • 1990-1994  (8)
  • 1993  (3)
  • 1991  (5)
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  • 1990-1994  (8)
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  • 1
    Electronic Resource
    Electronic Resource
    Immunomodulatory effects on rainbow trout, Oncorlynchus mykiss, injected with the extract of abalone, Haliotis discus hannai (1991)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of applied ichthyology 7 (1991), S. 0 
    Details
    ISSN: 1439-0426
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Rainbow trout, Oncorhynchus mykiss, injected with a water fraction extracted from abalone, Haliotis discus hannai, showed enhanced phagocytosis. This enhanced activity reached its maximum level 5 days after injection. The natural killer cell activities and the chemiluminescence responses of kidney leukocytes in fish treated with this fraction were also significantly increased, compared to those in albumin-treated fish. Rainbow trout injected intraperitoneally with this fraction showed an increased resistance to Vibrio anguillarum.〈section xml:id="abs1-2"〉〈title type="main"〉Zusammenfassung Immunomodulationseffekte bei Regenbogenforellen, Oncorhynchus mykiss, nach Injektion von Aba-lone-Entrakt, Haliotis discus hannaiBei Regenbogenforellen, Oncorynchus mykiss, denen ein wäßriger Extrakt der Abalone, Haliotis discus hannai, injiziert wurde, konnte eine gesteigerte Phagocytoseaktivität beobachtet werden. Diese Aktivi-tätssteigerung erreichte 5 Tage nach Verabreichung der Injektion ihr Maximum. Die natürliche Aktivi-tat von Killer-Zellen und die Chemoluminizenz-Reaktion der Nieren-Leukozyten in den mit dem Extrakt behandelten Fischen waren gegenüber Tieren, denen Albumin injiziert wurde, signifikant erhoht. Regenbogenforellen, denen der Abalone-Extrakt intraperitoneal injiziert wurde, zeigten eine erhohte Resistenz gegen Vibrio anguillarum.〈section xml:id="abs1-3"〉〈title type="main"〉Résumé Effects immunomodulatoires chez la truite arc-en-ciel, Onchorhynchus mykiss, traitie par des injections d'extraits d'onneaux, Haliotis discus hannai La truite arc-en-ciel, Onchorhynchus mykiss, traitie par injection d'une fraction aqueuse extraite d'ormeaux, Haliotis discus hannai, a montré une augmentation du taux de phagocytose. Cette augmentation de I'activité a atteint son niveau maximal cinq jours aprés injection. Les activitts naturelles des cellules tueuses et les résonses chimioluminescentes des leucocytes du rein des poissons traitis par cette fraction ont aussi significativement augmentis, par rapport ä celle des poissons traitis par de l'albumine. Les truites arc-en-ciel uaities par des injections intrapiritoniales de cette fraction ont montré une résistance accrue äVibrio anguillarum.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1439-0426.1991.tb00594.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    The detection of serum antibody to Renibacterium salmoninarum in pen-cultured coho salmon, Oncorhynchus kisutch (Walbaum) (1991)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 14 (1991), S. 0 
    Details
    ISSN: 1365-2761
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2761.1991.tb00594.x
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Enhancement of resistance to bacterial infection in rainbow trout, Oncorhynchus mykiss (Walbaum), by oral administration of bovine lactoferrin (1993)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 16 (1993), S. 0 
    Details
    ISSN: 1365-2761
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: Abstract Bovine lactoferrin was evaluated for its ability to enhance resistance of rainbow trout, Oncorhynchus mykiss (Walbaum), to infection with Vibrio anguillarum. Oral administration of lactoferrin (100 mg kg−1) to fish daily for 3 days prior to an intraperitoneal challenge with V. anguillarum resulted in increased survival rates, and enhanced resistance against Streptococcus sp., although to a lesser extent. In lactoferrin-treated fish, an increase in phagocytic and chemiluminescent (CL) activities of pronephros cells against V. anguillarum was observed. The phagocytic and CL activities of cells against Streptococcus sp. were also significantly increased. However, no in vitro bactericidal activities of lactoferrin against V. anguillarum or Streptococcus sp. were observed. This suggests that the lactoferrin enhanced the resistance of the rainbow trout against bacterial infection through the activation of phagocytes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2761.1993.tb01253.x
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  • 4
    Electronic Resource
    Electronic Resource
    Pharmacokinetics of flosequinan in elderly patients with chronic congestive heart failure (1993)
    Springer
    European journal of clinical pharmacology 44 (1993), S. 387-389 
    Details
    ISSN: 1432-1041
    Keywords: Flosequinan ; Congestive heart failure ; elderly ; pharmacokinetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary We have investigated the pharmacokinetics of the direct vasodilator flosequinan in elderly patients with congestive heart failure. Eight patients received a single dose of 50 mg, and 8 patients received once-daily treatment with 25 mg for two weeks. In the single dose study, the tmax of flosequinan was 2.5 h, Cmax was 1.17 μg · ml−1 and t1/2 was 5.63 h. The tmax of the metabolite BTS 53554 was 20.3 h, Cmax was 1.44 μg · ml−1 and t1/2 was 62.0 h. BTS 53554 accumulated gradually in the 14-day repeated dose study and steady-state was reached after approximately 2 weeks. Flosequinan was not found to accumulate. Adverse reactions were not observed in either the single or repeated dose study. It is advisable to consider renal function and body weight when flosequinan is to be administered to elderly patients with congestive heart failure. The initial dose should be 25 mg.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00316479
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Application of an indentation method to the fracture mechanics study of a polycrystalline graphite (1991)
    Springer
    Journal of materials science 26 (1991), S. 4208-4214 
    Details
    ISSN: 1573-4803
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract None of the conventional indentation techniques are applicable to carbon and graphite materials for determining fracture mechanics parameters because of the difficulty in introducing well-defined median/radial cracks. A novel indentation method is proposed in this work for fracture mechanics studies and then applied to a polycrystalline graphite fracture. The most prominent advantage of the indenter designed is that the residual stresses beneath the indentation impression, which prevail in conventional indentation methods (Knoop and Vickers indentations) and lead to crucial difficulties in fracture mechanics analysis, are negligibly small. This makes possible a quantitative study on the microstructural interaction between the indentation-induced micro-flaw and the natural intrinsic flaws of the material. The dependence of flexural strength of a polycrystalline graphite on the indentation-induced surface flaw size is also discussed by examining the microstructural scaling transition of fracture origin from the indentation-induced to the intrinsic flaws with diminishing indentation surface flaw. An important role of the Mrozowsky micro-crack system in the scaling transition is emphasized.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00553512
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  • 6
    Electronic Resource
    Electronic Resource
    The strength of pitch-based carbon fibre at high temperature (1991)
    Springer
    Journal of materials science 26 (1991), S. 1601-1604 
    Details
    ISSN: 1573-4803
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The strengths of some high modulus pitch-based carbon fibres have been determined up to 1300 °C in both air and nitrogen atmospheres. The fibres possessed Young's moduli of 700 GPa and were 10 μm in diameter. The strength of the fibres was seen to be gauge length dependent but to a lesser extent than is usual with PAN-based carbon fibres. The fibre strength was observed to increase with temperature as did the Weibull modulus.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00544669
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    Paper (German National Licenses)
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  • 7
    Electronic Resource
    Electronic Resource
    Application of an indentation method to the fracture mechanics study of a polycrystalline graphite (1991)
    Springer
    Journal of materials science 26 (1991), S. 4208-4214 
    Details
    ISSN: 1573-4803
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract None of the conventional indentation techniques are applicable to carbon and graphite materials for determining fracture mechanics parameters because of the difficulty in introducing well-defined median/radial cracks. A novel indentation method is proposed in this work for fracture mechanics studies and then applied to a polycrystalline graphite fracture. The most prominent advantage of the indenter designed is that the residual stresses beneath the indentation impression, which prevail in conventional indentation methods (Knoop and Vickers indentations) and lead to crucial difficulties in fracture mechanics analysis, are negligibly small. This makes possible a quantitative study on the microstructural interaction between the indentation-induced micro-flaw and the natural intrinsic flaws of the material. The dependence of flexural strength of a polycrystalline graphite on the indentation-induced surface flaw size is also discussed by examining the microstructural scaling transition of fracture origin from the indentation-induced to the intrinsic flaws with diminishing indentation surface flaw. An important role of the Mrozowsky micro-crack system in the scaling transition is emphasized.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02402970
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    Paper (German National Licenses)
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  • 8
    Electronic Resource
    Electronic Resource
    Abstracts of papers and posters Biopharmacy and Phamaceutcal Technology Meeting (1993)
    Springer
    Pharmacy world & science 15 (1993), S. 1-6 
    Details
    ISSN: 1573-739X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02297508
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    Paper (German National Licenses)
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