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  • 1990-1994  (6)
  • 1960-1964
  • 1993  (3)
  • 1992  (3)
Material
Years
  • 1990-1994  (6)
  • 1960-1964
Year
  • 1
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 72 (1992), S. 1821-1832 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Electrical resistance of Al-1 wt % Si thin-film conductors has been measured as a function of time t, temperature, and current polarity in order to investigate both generation and recovery of (microstructural) damage caused by electromigration. The fractional change of electrical resistance ΔR/R is characterized by three distinct stages: (i) undetectable ΔR/R during an incubation period τ; (ii) linear increase of ΔR/R with t−τ; and (iii) abrupt decrease of ΔR/R when polarity is reversed, followed by gradual resumption of the previous linear increase. Examination of the conductor surface during these three stages by scanning electron microscopy reveals: (i) undetectable microstructural damage; (ii) generation of (first) holes and (then) hillocks; and (iii) recovery followed by further generation of microstructural damage. Results are interpreted by (i) generation of stress σ in grain boundaries; (ii) formation of holes when σ exceeds a critical tensile stress σ+c and hillocks when σ exceeds a critical compressive stress σ−c (||σ+c|| 〈 ||σ−c||), and (iii) interchange of tensile and compressive stress by polarity reversal. The last stage, in fact, represents superposition of a continuation of the linear increase (degradation) of ΔR/R due to the applied current and an exponential decrease (healing) of ΔR/R, characterized by τ, due to stress relaxation. In general, damage and subsequent healing by electromigration involve a delicate balance between applied current, time, and spatial distribution of (elastic) tensile and compressive stress, (anelastic) formation of holes, and (plastic) formation of hillocks, as dictated by the concomitant microstructure.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 61 (1992), S. 276-278 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Time evolution of the fractional change of electrical resistance of passivated Al–1 wt% Si thin-film conductors is characterized by five distinct stages: (1) undetectable change during an incubation period, (2) subsequent linear increase, (3) saturation, (4) abrupt decrease when applied current is interrupted or reversed, and (5) erratic fluctuations at extended times. Results are interpreted in terms of generation of localized tensile and compressive stress by electromigration, resulting in (reversible) hole formation at grain boundary triple junctions, followed by complex combinations of hole movement, coalescence, and annihilation.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 61 (1992), S. 2987-2989 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Steady-state electromigration along grain boundaries in a monatomic polycrystalline thin film has been analyzed in a two-dimensional model by balancing the (applied) electric and (induced) stress driving forces to achieve a zero flux divergence. The continuity of chemical potential requires a unique stress normal to each of the three boundaries terminating at a given triple point. These stresses and the steady-state fluxes are determined by a set of linear equations subject to boundary conditions at the intersection of grain boundaries with the film edge (edge points). When the normal stress is assumed zero at all edge points, the stress typically attains maxima and minima at triple points, whereas, when the flux is assumed zero at all edge points, the stress typically builds up monotonically in the field direction.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Pediatric allergy and immunology 4 (1993), S. 0 
    ISSN: 1399-3038
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: In order to identify newborns at risk for atopic diseases, we developed a family questionnaire and selected specific answers which were suitable to identify atopic family members. The validity of the questionnaire was evaluated by the Phadiatop lest results of 793 mothers and 353 fathers. As both screening instruments do not measure the same, the Phadiatop test identifies scnsitization to inhalant allergens and the history reflects the clinical manifestation of atopic disease, the agreement between sensitization and manifestation is incomplete. Sensitivity and specificity of the questionnaire screening conditions to reproduce the Phadiotop lest result was 64% and 84% for mothers, and 58% and 88% for fathers, respectively. The relative risk for lifetime prevalence of atopic manifestations in Phadiatop positive over negative mothers was calculated to be 3. 88 (95% confidence interval = 3. 12 to 4. 81), and for Phadiatop positive over negative fathers to amount 4. 84 (95% confidence interval 3. 25 to 7. 23). A few relevant answers of 20 were identified by logistic regression analysis to predict the Phadiatop test result nearly, as well as the total questionnaire.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Archives of gynecology and obstetrics 254 (1993), S. 1454-1456 
    ISSN: 1432-0711
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1573-5001
    Keywords: Dihydrofolate reductase ; NMR ; 13C/15N labelled protein
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Summary 13C-based three-dimensional 1H−1H correlation experiments have been used to determine essentially complete 13C and 1H resonance assignments for the amino acid side chains of uniformly 13C/15N labelled L. casei dihydrofolate reductase in a complex with the drug methotrexate. Excellent agreement is observed between these assignments and an earlier set of partial assignments made on the basis of correlating nuclear Overhauser effect and crystal structure data, indicating that the tertiary structure of the enzyme is similar in solution and in the crystal state.
    Type of Medium: Electronic Resource
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