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  • 1990-1994  (5)
  • 1993  (5)
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  • 1990-1994  (5)
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  • 1
    Electronic Resource
    Electronic Resource
    On the origin of photoluminescence in spark-eroded (porous) silicon (1993)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 63 (1993), S. 2771-2773 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Photoluminescence measurements and high-resolution transmission electron microscopy studies on spark-treated (porous) silicon have been performed. Contrary to suggestions put forward by others, it has been found that spark erosion does not yield structures comparable to those obtained for irradiated, that is, damaged silica. Instead, evidence is given that spark treatment of single crystalline silicon wafers produces randomly oriented nanometer-sized silicon crystallites surrounded by a SiO2 matrix. This configuration is believed to be responsible for the observed room temperature visible photoluminescence.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.110792
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Characterization of the cardiac troponin I phosphorylation domain by 31P nuclear magnetic resonance spectroscopy (1993)
    s.l. : American Chemical Society
    Biochemistry 32 (1993), S. 13873-13878 
    Details
    ISSN: 1520-4995
    Source: ACS Legacy Archives
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/bi00213a016
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Polychlorinated biphenyls and chlorinated insecticides in plasma of Caspian terns: Relationships with age, productivity, and colony site tenacity in the great lakes (1993)
    Springer
    Archives of environmental contamination and toxicology 24 (1993), S. 320-331 
    Details
    ISSN: 1432-0703
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Notes: Abstract Chlorinated hydrocarbons such as polychlorinated biphenyls (PCBs) and chlorinated insecticides have often been detected in Great Lakes fish-eating birds at concentrations that are correlated with greater than expected embryo mortality and reduced reproductive success. Blood from 111 known-age, adult Caspian terns (Sterna caspia) nesting in several regions of the upper Great Lakes was collected in 1990 to examine bioavailability of PCBs, to compare concentrations of PCBs among nesting locations, and to determine relationships between concentrations of PCBs and age, productivity, and colony site tenacity. PCBs, DDE, dieldrin, and trans-nonachlor were detected in all the samples. Concentrations of PCBs were, on average, 10, 100, and 250 times greater than those of DDE, dieldrin, and trans-nonachlor, respectively. Concentrations of PCBs were not correlated with age, and were greater in Caspian terns from Saginaw and Green Bays than in Caspian terns from the North Channel and Georgian Bay. Concentrations of PCBs and DDE were significantly correlated with one-another and their accumulation patterns were the most similar among all the chemicals studied. Patterns of organochlorines as determined by cluster analysis were most similar for the nearest nesting locations. The bioaccumulation of PCBs in Great Lakes Caspian terns appeared to be seasonal and did not vary with adult age. A significant negative correlation was observed between mean concentrations of PCBs by region and percent terns returning to natal region. Those populations which were likely to be affected by PCBs were those nesting in Green Bay and Saginaw Bay.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01128730
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Recurrent mutations in the factor IX gene: founder effect or repeat de novo events (1993)
    Springer
    Human genetics 〈Berlin〉 92 (1993), S. 40-48 
    Details
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The investigation of 114 unrelated patients, representing about half the sample of the German haemophilia B population, enabled us to delineate the causative mutation in 103 (90.4%) haemophilic factor IX genes. Of these 103 cases 84 (81.6%) turned out to be unique molecular events, the remainder being repeats. Haplotype analysis revealed that the great majority, if not all, of these recurrent observations occurred independently. This conclusion is supported by our finding that three de novo mutations could be demonstrated at two sites of frequent mutation. A further 20 de novo events could be established in an unselected sample of 37 families with sporadic haemophilia B and 37 families with a history of the disease. Altogether, the germ line of origin could be determined in 21 of these 23 cases, thereby indicating a ratio of male to female mutation rates close to 2. On the basis of the data available, it is becoming clear that rearrangements in the factor IX gene (35.4% of de novo cases) are responsible for haemophilia B at a higher frequency than has been observed today (12.3%). More than two-thirds of the de novo cases cause the severe form of the disease, thereby reflecting the deficit of these haemophilic genes in the actual gene pool because of excess mortality in the past. In addition 40% (12/30) of the de novo single-base mutations were transitions at CpG dinucleotides. Compared with the expected at-random frequency, this observation indicates an 83-fold enhancement of mutation at CpG.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00216143
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Interaction sites on phosphorylase kinase for calmodulin (1993)
    Springer
    Molecular and cellular biochemistry 127-128 (1993), S. 19-30 
    Details
    ISSN: 1573-4919
    Keywords: phosphorylase kinase ; calmodulin ; calmodulin-binding peptides ; Ca2+-binding
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract Holophosphorylase kinase was digested with Glu-C specific protease; from the peptide mixture calmodulin binding peptides were isolated by affinity chromatography and identified by N-terminal sequence analysis. Two peptides originating from the α subunit, having a high tendency to form a positively charged amphiphilic helix and containing tryptophane, were synthesized. Additionally, a homologous region of the β subunit and a peptide from the α subunit present in a region deleted in the α′ isoform were also selected for synthesis. Binding stoichiometry and affinity were determined by following the enhancement in tryptophane fluorescence occurring upon 1:1 complex formation between these peptides and calmodulin. Finally, Ca2+ binding to calmodulin in presence of peptides was measured. By this way, the peptides α 542–566, α 547–571, α 660–677 and β 597–614 have been found to bind specifically to calmodulin. Together with previously predicted and synthesized calmodulin binding peptides four calmodulin binding regions have been characterized on each the α and β subunits. It can be concluded that endogenous calmodulin can bind to two calmodulin binding regions in γ as well as to two regions in α and β. Exogenous calmodulin can bind to two regions in α and in β. A binding stoichiometry of 0.8mol of calmodulin/αβγδ protomer of phosphorylase kinase has been determined by inhibiting the ubiquitination of calmodulin with phosphorylase kinase. Phosphorylase kinase is half maximally activated by 23nM calmodulin which is in the affinity range of calmodulin binding peptides from β to calmodulin. Therefore, binding of exogenous calmodulin to β activates the enzyme. A model for switching endogenous calmodulin between α, β and γ and modulation of ATP binding to α as well as Mg2+/ADP binding to β by calmodulin is presented.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01076754
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    Paper (German National Licenses)
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