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  • 1990-1994  (14)
  • 1950-1954
  • 1915-1919
  • 1994  (14)
  • 1
    Electronic Resource
    Electronic Resource
    The use of polytetrafluoroethylene in the production of high-density bonded Nd-Fe-B magnets : The 6th joint magnetism and magnetic materials (MMM)−intermag conference (1994)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 76 (1994), S. 6831-6833 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Rotary forging has been used to produce high-density bonded magnets from rapidly quenched Nd-Fe-B based ribbons [MQP-D, of nominal composition 28%Nd-56%Fe-15%Co-1%B (wt %)]. Polytetrafluoroethylene (PTFE), when used as an additive (5%–15% by volume) has been found to act as an effective binder and greatly enhances the forgeability of the MQI, allowing higher forging pressures to be used. Densities of up to 98% of the fully dense composite have been achieved. The forging process can be undertaken in air at room temperature. Magnetically, the compacts are comparable to conventional epoxy resin bonded MQI, with energy products of up to 84 kJ/m3. Equivalent volume fractions of MQI (∼83.5 vol %) have been achieved in the compacts with increased PTFE content due to the displacement of pores by the PTFE. The effect of PTFE content on the mechanical strength of the compacts has been assessed and it has been found that strength increases with increasing PTFE content, consistent with the reduction in porosity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.358145
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  • 2
    Electronic Resource
    Electronic Resource
    Hyaline globules in ovarian tumours: Sir (1994)
    Oxford, UK : Blackwell Publishing Ltd
    Histopathology 25 (1994), S. 0 
    Details
    ISSN: 1365-2559
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2559.1994.tb01343.x
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  • 3
    Electronic Resource
    Electronic Resource
    The effect of oxygen concentration on changes in the microbial population, temperature and dry-matter content in grass silage (1994)
    Oxford, UK : Blackwell Publishing Ltd
    Grass and forage science 49 (1994), S. 0 
    Details
    ISSN: 1365-2494
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: The effects of transfusing cores of grass silage with mixtures of oxygen and nitrogen containing 0%, 0·2%, 2%, 5% and 20% oxygen were investigated. Changes in populations of yeasts, lactobacilli and streptococci were measured and the relationship between populations after 7 days' transfusion and oxygen concentration were tested against the predictions of two models, based on Monod and logistic growth functions. Yeasts were related to oxygen by the Monod model, while lactobacilli and streptococci were related by the logistic model. The differences were ascribed to yeasts initiating deterioration by growing aerobically, while lactobacilli and streptococci grew fermentatively once the environment had changed following yeast growth. Dry-matter losses were related to oxygen by the Monod model. Changes in temperature were related to dry matter loss (through measurements of CO2 evolution) using a simple heat balance model.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2494.1994.tb01991.x
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  • 4
    Electronic Resource
    Electronic Resource
    The incidence and severity of postoperative nausea and vomiting in patients exposed to positive intra-operative suggestions (1994)
    Oxford, UK : Blackwell Publishing Ltd
    Anaesthesia 49 (1994), S. 0 
    Details
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: In a double-blind study, the effects of positive intra-operative suggestions on the incidence and severity of postoperative nausea and vomiting were studied in 60 patients randomly selected to undergo routine major gynaecological surgery. Patients who received positive suggestions suffered significantly less nausea and vomiting in the 24 h after surgery.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2044.1994.tb14190.x
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  • 5
    Electronic Resource
    Electronic Resource
    Supernova 1993k — first photometric results (1994)
    Springer
    Experimental astronomy 5 (1994), S. 151-152 
    Details
    ISSN: 1572-9508
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The 61 cm Lowell telescope at Perth Observatory has been automated by the Perth Astronomy Research Group (PARG) for the detection, confirmation and follow-up studies of supernovae and other transient events. This search program complements similar searches operating in the Northern Hemisphere, such as the Berkeley Supernova Search. The first supernova found by our search program, SN 1993k, was discovered on March 28, 1993 (IAUC 5733). The discovery has been made with the telescope in fully automated mode, including automated image analysis. We are currently imaging some 80 galaxies per night. Photometric methods for the analysis of lightcurves are at present being implemented.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01583827
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  • 6
    Electronic Resource
    Electronic Resource
    Predicting outcome in ICU patients (1994)
    Springer
    Intensive care medicine 20 (1994), S. 390-397 
    Details
    ISSN: 1432-1238
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Conclusions Considerable time and energy has been invested in the conception, modelling and evaluation of sophisticated severity scoring systems for ICU patients. These systems are created to enhance the precise estimation of hospital mortality for large ICU patient populations. Their current low sensitivity precludes their use for predicting out-come for individual ICU patients. However, severity scores can already be valuable for predicting mortality in groups of general ICU patients, and are very useful in the clinical trial setting. Outcome of ICU therapy, however, should incorporate more than mortality. Morbidity, disability and quality of life should also be taken into account; these factors were not taken into consideration in the design of the currently available severity scoring systems. At present, the severity scores have a very limited or no role in clinical decision-making for an individual patient, because they are based on a number of physiological and disease-oriented variables collected during the first 24 h after ICU admission. Future developments and subsequent validation of the dynamic process of clinical, physiological and organ-specific variables could improve the sensitivity and the value of severity scoring. Further collaborative developmental work in this field should be encouraged and supported across Europe and North America.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01720917
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  • 7
    Electronic Resource
    Electronic Resource
    Histological study of pancreatic beta-cell loss in relation to the insulitis process in the non-obese diabetic mouse (1994)
    Springer
    Histochemistry and cell biology 101 (1994), S. 263-269 
    Details
    ISSN: 1432-119X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Non-obese diabetic (NOD) mice spontaneously develop an autoimmune diabetes with higher incidence in females than in males. In order to elucidate possible factors involved in the different incidence of diabetes between male and female mice, we studied the progression of pancreatic beta-cell loss in relation to mononuclear cell infiltration of the pancreas (insulitis). We examined the pancreas of 76 NOD mice (39 males and 37 females) of different ages. The beta-cell content was assessed by immunoperoxidase staining of sections with an anti-insulin serum and the severity of insulitis was determined by haematoxylin staining of the same sections. A semi-quantitative criterion was used to grade both parameters. The results showed that females have a faster loss of beta-cell mass, which progressively decreases with the increase of severity of insulitis. In males, a medium to severe degree of insulitis is required before initial loss of beta cells occurs. Under the age of 10 weeks there was a significantly lower content of beta cells in females than males (2.84±0.03 vs 2.67±0.07; P=0.02). Since we never observed a significant difference in the degree of mononuclear cell infiltration in age-matched males and females, these data support the hypothesis of weaker beta-cell resistance to immunological attack in female mice. Thus beta-cell sensitivity, in addition to immunological activity, is an important factor in the pathogenesis of insulin dependent diabetes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00315913
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  • 8
    Electronic Resource
    Electronic Resource
    Effect of cyclosporine A on long-term allograft function in pediatric renal transplant recipients (1994)
    Springer
    Pediatric nephrology 8 (1994), S. 566-569 
    Details
    ISSN: 1432-198X
    Keywords: Cyclosporine A ; Kidney transplantation ; Allograft function ; Iothalamate clearance
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract There have been concerns regarding long-term adverse effects of cyclosporine A (CSA) on renal allograft function. In a retrospective study, we compared long-term allograft function up to 70 months after renal transplantation in pediatric recipients treated with and without CSA, using iothalamate clearance to assess glomerular filtration rate. Patients received CSA, prednisone, and azathioprine (CSA group,n=16) or prednisone and azathioprine alone (Pred/AZA,n=11). At 48 months post transplant, the iothalamate clearances (mean±SD) were 57.9±26.8 ml/min per 1.73 m2 in the CSA group and 68.5±20.2 in the Pred/AZA group (P〉0.05). The mean of the slopes of individual iothalamate clearances versus time during the first 70 months following transplantation were −0.156 in the CSA group and −0.095 in the Pred/AZA group. Neither slope was statistically different from zero. These data suggest that allograft function is not significantly depressed by CSA at 48 months post transplantation and that there is no greater rate of decline in allograft function up to 70 months post transplantation in patients receiving CSA when compared with the AZA/Pred group.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00858128
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  • 9
    Electronic Resource
    Electronic Resource
    Regulation of the gating of the sheep cardiac sarcoplasmic reticulum ca2+-release channel by luminal Ca2+ (1994)
    Springer
    The journal of membrane biology 137 (1994), S. 215-226 
    Details
    ISSN: 1432-1424
    Keywords: Ca2+-release channels ; Sarcoplasmic reticulum ; Cardiac ; Sulmazole
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract We investigated the effects of changes in luminal [Ca2+] on the gating of native andpurified sheep cardiac sarcoplasmic reticulum (SR) Ca2+-release channels reconstituted intoplanar phospholipid bilayers. The open probability (P o )of channels activated solely by cytosolic Ca2+ was greater at positive than negative holding potentials. Channels activatedsolely by 10 μm cytosolic Ca2+ exhibited no change in steady-stateP o or in the relationship betweenP o and voltage when the luminal[Ca2+] was increased from nanomolar to millimolar concentrations. In the absence of activating concentrationsof cytosolic Ca2+, the channel can be activated by the phosphodiesterase inhibitor sulmazole (AR-L 115BS). However, cytosolicCa2+-independent activation of the channel by sulmazole requires luminal Ca2+. In the presence ofsulmazole, at picomolar luminal [Ca2+] the channel remains completely closed. Increasing the luminal [Ca2+]to millimolar levels markedly increases the P o via an increase in theduration of open events. The P o and duration of the sulmazole-activated, luminalCa2+-dependent channel openings are voltage dependent. In the presence of micromolar luminal Ca2+, theP o and duration of sulmazole-activated openings are greater atnegative voltages. However, at millimolar luminal [Ca2+], long openings are also observed at positive voltages and theP o appears to be similar at positive and negative voltages. Our findings indicate thatthe regulation of channel gating by luminal Ca2+ depends on the mechanism of channel activation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00232590
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  • 10
    Electronic Resource
    Electronic Resource
    Adenosine discriminates between the caffeine and adenine nucleotide sites on the sheep cardiac sarcoplasmic reticulum calcium-release channel (1994)
    Springer
    The journal of membrane biology 137 (1994), S. 169-177 
    Details
    ISSN: 1432-1424
    Keywords: Adenosine ; Sarcoplasmic reticulum ; Cardiac Ca2+-release channel ; Caffeine ; Adenine nucleotides
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract Calcium-release channels of sheep cardiac sarcoplasmic reticulum were incorporated into phosphatidylethanolamine bilayers and single channel currents were recorded under voltage-clamp conditions. The effect of adenosine on single channel conductance and gating was investigated, as were the interactions between adenosine and caffeine and adenosine and α,β-methylene ATP. Addition of adenosine (0.5–5 mm) to the cytosolic but not the luminal side of the membrane increased the open probability of single calcium-activated calcium-release channels by increasing the frequency and duration of open events, yielding an EC50 of 0.75 mm at 10 μm activating Ca2+. Addition of 1 mm caffeine potentiated the effects of adenosine at 10 or 100 μm-activating cytosolic calcium, but had no effect on the inability of adenosine to activate the channel at 80 pmcalcium, suggesting discrete sites of action on the calcium-release channel for adenosine and caffeine. In contrast, addition of 100 μm α,β-methylene-ATP decreased single channel open probability in the presence of adenosine, suggesting that these compounds act on the same site on the channel. Activation of single channel opening by adenosine, or by adenosine together with caffeine, had no effect on single channel conductance or the Ca2+/Tris+ permeability ratio. Channels activated by adenosine were characteristically modified by ryanodine and blocked by μm ruthenium red or mm magnesium. These results show that adenosine activates the sheep cardiac sarcoplasmic reticulum Ca2+-release channel by increasing the frequency and duration of open events in a Ca2+-dependent manner. The receptor site on the channel for adenosine is distinct from that for caffeine but probably the same as that for adenine nucleotides.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00233486
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