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  • 1
    Electronic Resource
    Electronic Resource
    A clinical and histopathological study of factors affecting MRI signal intensities of pituitary adenomas (1994)
    Springer
    Neuroradiology 36 (1994), S. 298-302 
    Details
    ISSN: 1432-1920
    Keywords: Pituitary adenoma ; MRI ; Immunohistochemistry ; Pituitary hormones
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Our aim was to elucidate the factors which determine the MRI signal intensities of pituitary adenomas. We examined 51 patients with surgically-confirmed pituitary adenomas. Using a spin-echo pulse sequence (SE 500/15), coronal and sagittal images (3 mm slices) were obtained. Signal intensities on T1-weighted images were measured in the parenchyma of the adenoma and in normal grey matter. The relative intensity of the adenoma was assessed by calculating the ratio of its signal intensity to that of the normal grey matter of the same patient. Parafin-embedded sections were used for haematoxylin and eosin staining. The number of cells in a prescribed area was counted, and the mean of five such counts was taken as the cell density. Immunohistochemically stained sections using antibodies for various pituitary hormones were similarly examined; the ratio of the total number of hormone-positive cells to the overall total number of adenoma cells was calculated. Four independent variables were used in the analysis: the age of the patient, the maximum diameter of the adenoma, the cell density and the proportion of hormone-positive cells in the adenoma and, with the signal intensity ratio as the dependent variable, a multiple regression analysis was performed. This revealed that the the greatest influence upon the signal intensities on T1-weighted images was the proportion of hormone positive cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00593265
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Hydrophilic polymer-coated guide wire combined with progressive suppleness pursil catheter for safer, more definitive embolisation of arteriovenous malformations (1994)
    Springer
    Neuroradiology 36 (1994), S. 326-329 
    Details
    ISSN: 1432-1920
    Keywords: Arteriovenous malformations ; Embolisation ; Guide wire ; Minicatheter ; Progressive suppleness pursil catheter ; Superselective catheterisation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract For safe, more definitive embolisation of arteriovenous malformations, improved selectivity of the catheter is desirable. This report describes the advantage of the combined use of a progressive suppleness pursil catheter and a hydrophilic polymer-coated guide wire, together with precaution against complications. In 14 patients, 27 vessels were catheterised with this. Chemical embolisation using oestrogen alcohol and polyvinyl acetate was carried out only if sufficiencytly superselective catheterization was achieved with negative results on a provocation test. Chemical embolisation was successful in 25 vessels, but in three vessels catheterised very distally, it required much more time to withdraw the catheter because of the friction between it and the wall of the vessel.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00593273
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
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