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  • 1
    Electronic Resource
    Electronic Resource
    Crystals of Ligand-Free Bovine Neurophysin II (1996)
    Copenhagen : International Union of Crystallography (IUCr)
    Acta crystallographica 52 (1996), S. 946-949 
    Details
    ISSN: 1399-0047
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Notes: A modified neurophysin, des 1-6 bovine neurophysin II, has been crystallized in the absence of bound hormone or hormone analogue. These crystals represent the first crystals of ligand-free neurophysin, and are essential for understanding neurophysin–hormone recognition as well as hormone-induced neurophysin dimerization. The crystals diffract to beyond 1.8 Å resolution, belong to space group P3121 (or P3221) with a = 48.86, c = 78.61 Å, and contain one molecule per asymmetric unit.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0907444996005513
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Nicotine effects on adults with attention-deficit/hyperactivity disorder (1996)
    Springer
    Psychopharmacology 123 (1996), S. 55-63 
    Details
    ISSN: 1432-2072
    Keywords: Nicotine ; Attention Deficit/Hyperactivity Disorder ; Attention ; Treatment ; Nicotine skin patches
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Several lines of evidence suggest that nicotine may be useful in treating the symptoms of Attention-Deficit/Hyperactivity Disorder (ADHD). The current study was an acute, placebo-controlled double-blind experiment to determine whether nicotine might be useful as an alternative treatment of adults with ADHD symptomatology. Six smokers and 11 nonsmokers who were outpatient referrals for ADHD were diagnosed by DSM-IV criteria. Measures of treatment effect included the Clinical Global Impressions (CGI) scale, Hopkins' symptom check list (SCL-90-R), the Profile of Mood States (POMS), Conners' computerized Continuous Performance Test (CPT), the Stroop test, and an interval-timing task. The smokers underwent overnight deprivation from smoking and were given a 21 mg/day nicotine skin patch for 4.5 h during a morning session. The nonsmokers were given a 7 mg/day nicotine skin patch for 4.5 h during a morning session. Active and placebo patches were given in a counterbalanced order approximately 1 week apart. Nicotine caused a significant overall nicotine-induced improvement on the CGI. This effect was significant when only the nonsmokers were considered, which indicated that it was not due merely to withdrawal relief. Nicotine caused significantly increased vigor as measured by the POMS test. Nicotine caused an overall significant reduction in reaction time (RT) on the CPT, as well as, with the smokers, a significant reduction in another index of inattention, variability in reaction time over trial blocks. Nicotine improved accuracy of time estimation and lowered variability of time-estimation response curves. Because improvements occurred among nonsmokers, the nicotine effect appears not to be merely a relief of withdrawal symptoms. It is concluded that nicotine deserves further clincal trials with ADHD.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02246281
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Fresip: A mission to determine the character and frequency of extra-solar planets around solar-like stars (1996)
    Springer
    Astrophysics and space science 241 (1996), S. 111-134 
    Details
    ISSN: 1572-946X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract FRESIP (FRequency of Earth-Sized Inner Planets) is a mission designed to detect and characterize Earth-sizes planets around solar-like stars. The sizes of the planets are determined from the decrease in light from a star that occurs during planetary transits, while the orbital period is determined from the repeatability of the transits. Measurements of these parameters can be compared to theories that predict the spacing of planets, their distribution of size with orbital distance, and the variation of these quantities with stellar type and multiplicity. Because thousands of stars must be continually monitored to detect the transits, much information on the stars can be obtained on their rotation rates and activity cycles. Observations of p-mode oscillations also provide information on their age and composition. These goals are accomplished by continuously and simultaneously monitoring 500 solar-like stars for evidence of brightness changes caused by Earth-sized or larger planetary transits. To obtain the high precision needed to find planets as small as the Earth and Venus around solar-like stars, a wide field of view Schmidt telescope with an array of CCD detectors at its focal plane must be located outside of the Earth's at mosphere. SMM (Solar Maximum Mission) observations of the low-level variability of the Sun (∼1:100,000) on the time scales of a transit (4 to 16 hours), and our laboratory measurements of the photometric precision of charge-coupled devices (1:100,000) show that the detection of planets as small as the Earth is practical. The probability for detecting transits is quite favorable for planets in inner orbits. If other planetary systems are similar to our own, then approximately 1% of those systems will show transits resulting in the discovery of 50 planetary systems in or near the habitable zone of solar-like stars.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00644220
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Nutrient and nutritional evaluation of sinasin prepared in two ways (1996)
    Springer
    Plant foods for human nutrition 49 (1996), S. 139-145 
    Details
    ISSN: 1573-9104
    Keywords: Sinasin ; Rice flat bread ; Food preparation ; Kanuri diet ; Proximate composition ; Nutrition ; Protein efficiency ratio ; Food efficiency ratio ; Borno State ; Nigeria
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Abstract Two types of sinasin, a rice-based fermented kanuri flat bread, were prepared and evaluated for their nutrient content and nutritional qualities. The preparation of the sinasin entailed using ‘traditional’ and ‘developed’ methods. The nutritional qualities of the products were evaluated in Wistar-strain albino rats using the Food Efficiency Ratio (FER), and Protein Efficiency Ratio (PER) methods. There was a higher protein content (11.11 percent) in the traditional sinasin than in the developed sinasin (9.93 percent). However, a one-way analysis of variance indicated no significant difference in FER, but a significantly different mean PER (p〈0.01) of 1.3 and 1.5 for the traditional and developed sinasin respectively. The two methods of preparation of the sinasin, their nutrient composition and nutritional qualities are described in this paper.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01091971
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    Paper (German National Licenses)
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