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  • 1
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 85 (1999), S. 4071-4075 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Nanoscale In0.53Ga0.47As/In0.52Al0.48As multiquantum wells structures were studied by photocurrent spectroscopy. Photocurrent spectra showed clear steplike structures accentuated by exciton peaks. Many interband transitions were assigned from the spectral structure. As peaks of forbidden transitions, which appeared in large reverse bias voltages, were extrapolated to zero bias voltage on the photocurrent spectra, transition energies were estimated in a square potential well. New estimation methods of valence band parameters, heavy hole effective mass and valence band offset, were derived from a saturation of the heavy hole subband in the valence potential well, using the envelope function model in the effective mass approximation. The heavy hole effective mass in a direction normal to the quantum well plane and the valence band offset were 0.38m0 and 0.22 eV. © 1999 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: We have achieved long-pulse plasma heating using a negative-ion-based neutral beam injector (NBI) in the large helical device (LHD), where the confinement magnetic field is generated by only external superconducting coils. In the initial long-pulse experiments at lower power than that in short-pulse experiments, 80 keV–1.1 MW NBI heating lasted for 10 s with a little increase in the plasma density at the pulse end. Almost steady-state plasma heating was achieved for 21 s with 66 keV–0.6 MW NB injection. Plasma relaxation oscillation phenomena at a period of 1–2 s were also observed for 20 s. Above 1 keV plasma was easily sustained with a long-pulse NBI heating in LHD, without the current drive nor the disruption in tokamaks. Negative ion source operation was stable and the cooling water temperature rise of beam accelerator grids was nearly saturated with a temperature rise below 10 °C. For a higher power injection, the pulse duration is determined by the beam blocking, where the reionization loss is exponentially increased together with an increase in outgas in the injection port. The port conditioning by a careful repetition of injection is effective to the extension of the injection duration and the plasma maintenance duration. The initial long-pulse NBI heating at the reduced power has demonstrated an ability of steady-state operation in superconducting LHD. © 1999 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: A phase sensitive heterodyne polarimeter was installed on compact helical system (CHS). An HCN laser (337 μm) and Schottky barrier diodes are used for the radiation source and for detection, respectively. By using a phase sensitive heterodyne scheme, the Faraday rotation angle can be measured from the phase variations caused by the phase difference between the right- and left-handed waves in the magnetized plasma. The purpose of the polarimeter on CHS is for a stable density monitor which is free from fringe jump and for the measurements of the internal magnetic field induced by the plasma current. The present resolution of the Faraday rotation angle is 0.1° with 10 ms time resolution and 1° with 1 ms. These are mainly determined by the laser instability. © 1999 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: We developed a 19.6 nm laser x-ray laser grid-image refractometer (XRL-GIR) to diagnose laser-hole boring into overdense plasmas. The XRL-GIR was optimized to measure two-dimensional electron density perturbation on a scale of a few tens of μm in underdense plasmas. Electron density profiles of laser-produced plasmas were obtained for 1020–1022 cm−3 with the XRL-GIR and for 1019–1020 cm−3 from an ultraviolet interferometer, the profiles of which were compared with those from hydrodynamic simulation. By using this XRL-GIR, we directly observed laser channeling into overdense plasmas accompanied by a bow shock wave showing a Mach cone ascribed to supersonic propagation of the channel front. © 1999 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: In the National Institute for Fusion Science, the large helical device (LHD) (R=3.9 m, ap=0.65 m, B=3–4 T) was constructed in Toki City on January, 1998. The LHD is a torsatron/heliotron type device with a superconducting helical winding of pitch parameters of l/m=2/10 and three sets of superconducting poloidal coils. A two color millimeter-wave interferometer has been developed for the measurement of line integral electron density on the horizontal midplane of the LHD. To overcome the effects of the change in the transmission path length (∼100 m) during long pulse plasmas (10–1800 s), we have applied two color interferometry at 140 and 285 GHz. © 1999 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 70 (1999), S. 707-709 
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: A multichannel far-infrared laser interferometer system has been developed for the measurement of the spatial and temporal behaviors of the electron density on the Large Helical Device (LHD) at the National Institute for Fusion Science. Of several candidates for high power laser sources a 119 μm CH3OH laser was taken as a probing light. The optical configuration is of the Michelson interferometer type with 13 channels. The optical system of the interferometer is mounted on a massive stainless frame floated on three vibration isolating mounts. The resolution of the fringe counters is 1/100 fringes, and it corresponds to a line averaged density of 5.6×1016 m−3 at the central chord. Preliminary results have been obtained in the initial experiments on the LHD. © 1999 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Physics of Plasmas 6 (1999), S. 2855-2861 
    ISSN: 1089-7674
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Long-scale jet-like x-ray emission was observed in the experiments on the interactions of 100 TW laser light with plasmas. The jet formation is investigated by simulations with a two-dimensional particle code. When an S-polarized intense laser is irradiated obliquely on an overdense plasma, collimated MeV electrons are observed from the critical surface in the specular reflection direction. These electrons are found to be accelerated through the coronal plasma by the reflected laser light, which was modulated at the reflection point. The quasisteady magnetic channel occurs simultaneously and collimates the energetic electrons along the specular direction. In the case of P-polarized laser, it is found that an outgoing electron stream is induced at the critical surface due to Brunel mechanism. Megagauss quasistatic magnetic fields are generated and pinch the electron stream. The angle of ejected electron depends on the electron's energy. The emission direction of the jet generated by the P-polarized light is determined by the canonical momentum conservation along the target surface. © 1999 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 74 (1999), S. 653-655 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: We have developed a technique to form Si microstructures at preassigned positions on Si substrates. The key element of this technique is resistless patterning of ultrathin SiO2 mask layers by direct electron-beam exposure. Selective-area growth of Si was accomplished by two different chemistries: flow-modulated plasma-enhanced chemical vapor deposition (CVD) at 473 K or ultra-high-vacuum CVD at 853 K. Epitaxial deposition was achieved by the latter growth method when a mask layer with minimum thickness for deposition selectivity (approximately 0.2 nm) was employed. © 1999 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1432-8798
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary.  The hemagglutinin (H) protein of the measles virus (MV) Edmonston strain induced cell fusion in Cos (monkey) and B95a (marmoset) cells, when co-expressed with the fusion (F) protein, whereas the H protein of the wild-type KA strain induced fusion in B95a cells, but not in Cos cells. Asparagine residue at position 481 of the KA H protein was replaced by various amino acids through site-directed mutagenesis. Substitution with tyrosine, which was found at position 481 of the Edmonston H protein, enabled the mutant KA H protein (N481Y) to induce cell fusion in Cos cells co-expressing the F protein, which could be completely blocked by anti-CD46 antibody. This mutant, however, did not cause CD46 downregulation, unlike the Edmonston H protein. The other H protein mutants (N481S, N481T, N481D, N481H, N481F) did not produce syncytia in Cos cells. On the other hand, all of the mutants retained the ability to induce cell fusion in B95a cells. Thus, while tyrosine at position 481 was indispensable for the MV H protein’s interaction with CD46, the residue at this position does not appear to be critically involved in the interaction with the receptor for wild-type strains present on B95a cells.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1432-0827
    Keywords: Key words: C-type natriuretic peptide — Guanylate cyclase-B — Osteogenic cell — ROB-C26 — Dexamethasone.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Abstract. There is recent evidence that natriuretic peptides are important regulators of bone and cartilage, although they were originally identified as the cardiac hormones causing natriuresis and hypotension. Three members of natriuretic peptide family are known: atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), and C-type natriuretic peptide (CNP). The biologically active receptors for these peptides are particulate guanylate cyclases; the two known types are GC-A and GC-B. ANP and BNP have high affinities for GC-A, and CNP is the preferred ligand for GC-B. In this paper we report the results of our study of the expression and possible role(s) of natriuretic peptides in the ROB-C26 cell, which is an osteogenic cell line with multiple potentials for differentiating into myoblast, osteoblast, and adipocyte. ROB-C26 cells produced cGMP in response to natriuretic peptides at both their basal state and after enhanced differentiation into osteoblast which was induced by bone morphogenetic protein [(BMP)-2]. CNP was far more potent than ANP in cGMP production. In contrast, enhanced differentiation into adipocyte by dexamethasone resulted in the marked decrease in their responsiveness to natriuretic peptides. Although the messages for GC-A and GC-B were demonstrated by Northern blot analysis at both the basal stage and after BMP treatment, they were down-regulated after dexamethasone treatment. The presence of CNP was shown by RT-PCR and immunohistochemistry in ROB-C26 cells. C3H10T1/2, which is another and more primitive mesenchymal cell line, also produced cGMP in response to CNP, and less potently to ANP. Culturing ROB-C26 cells with CNP or 8-bromo cGMP decreased [3H]thymidine uptake and slightly increased the message for alkaline phosphatase, which is a marker for osteoblast differentiation. These results suggest that the CNP/GC-B system is preferentially expressed in the cells of osteogenic lineage and their expression is down-regulated with differentiation into adipocyte lineage. The CNP/GC-B system is likely to be an autocrine/paracrine regulator of osteoblast growth and differentiation.
    Type of Medium: Electronic Resource
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