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  • 2000-2004  (8)
  • 1980-1984
  • 1970-1974
  • 2002  (8)
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  • 2000-2004  (8)
  • 1980-1984
  • 1970-1974
Year
  • 1
    Electronic Resource
    Electronic Resource
    Modified electron cyclotron resonance source design for 3He accelerator mass spectroscopy (abstract) : Papers from the Ninth International Conference on Ion Sources (2002)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 73 (2002), S. 887-887 
    Details
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: The 10 GHz ECR-I ion source at ATLAS is being modified to create a small inner volume within the main plasma chamber to reduce the residual helium background gas load. This effort is part of an experiment to measure the residual concentration of 3He in highly isotopically enriched 4He samples. The modification consists of a new extractor electrode on which is integrally mounted a 2.5-cm-diam quartz tube of approximately 8 cm length. Energizing just the extraction coil produces an ECR only inside the quartz volume. The quartz tube is pumped only through the 1-mm-diam extraction hole. rf power is provided by propagation through the main plasma tank acting as a multimode waveguide. The source must operate in the pressure regime of 10–200 mTorr in order to achieve sufficient sensitivity to measure a 3He/4He ratio of approximately 1×10−15. Results of these tests and the operation of the source in this highly unusual mode will be presented. © 2002 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1432461
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Techniques for the measurement of ionization times in ECR ion sources using a fast sputter sample and fast gas valve : Papers from the Ninth International Conference on Ion Sources (2002)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 73 (2002), S. 548-551 
    Details
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: Two techniques for the discrete injection of material into an Electron Cyclotron Resonance ion source (ECRIS) have been developed for the purpose of measuring the ionization and confinement times of ion species. Previously only solid materials in conjunction with a pulsed laser were used in these studies due to the discrete material introduction produced by this configuration. The first method replaces the pulsed laser with a fast high voltage pulse applied to a sputter sample. The high voltage pulse has a rise time of 100 ns, fall time of 80.0 μs, and variable pulse duration. The second method utilizes a fast-pulsed gas valve capable of producing a gas pulse 160 μs in width. These pulse widths are well below the ionization times of the lower charge states and thus allows for time measurements to be made of all charge states. Both of these techniques can be employed to study the effects of rf power, coil configuration, biased disk, and gas mixing on ionization and confinement times. Rise times for neon, argon, and gold will be presented. © 2002 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1430273
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Bovine serum albumin enhances nicotinic acetylcholine receptor function in mouse thalamic synaptosomes (2002)
    Oxford, UK : Blackwell Science Ltd
    Journal of neurochemistry 83 (2002), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Bovine serum albumin (BSA) enhances nicotinic agonist-induced 86Rb+ efflux from synaptosomal fractions of the mouse thalamus, but how it does so is not understood. The experiments reported here indicated that BSA enhancement of nicotinic acetylcholine receptor function was rapid, reversible, depended on BSA concentration, and occurred at all points of the nicotinic agonist concentration-response curve. We hypothesized that BSA-extractable compounds, such as long-chain fatty acids, were responsible for inhibiting nicotinic responses in the absence of BSA. The hypothesis was tested by applying arachidonic, linolenic, or oleic acids in the absence of BSA after an initial prewash with BSA. All three fatty acids exhibited a rapid, concentration-dependent inhibition of nicotinic-agonist stimulated ion flux. Concentration-response curves produced after 30 s of pre-treatment with arachidonic acid were similar to those seen when BSA was completely absent. The effects of pre-treatment were reversed immediately by the introduction of BSA. Furthermore, no effects of fatty acids were observed when preparations were continuously exposed to BSA or when BSA was continuously absent. These results suggest that the removal of endogenous, inhibitory compounds is largely responsible for the rapid, potentiating action of BSA at nicotinic acetylcholine receptors expressed in the mouse thalamus.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1471-4159.2002.01135.x
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  • 4
    Electronic Resource
    Electronic Resource
    Regulation and Expression of Progesterone Receptor mRNA Isoforms A and B in the Male and Female Rat Hypothalamus and Pituitary Following Oestrogen Treatment (2002)
    Oxford, UK : Blackwell Science, Ltd
    Journal of neuroendocrinology 14 (2002), S. 0 
    Details
    ISSN: 1365-2826
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Progesterone receptors play a central role in neuroendocrine and behavioural regulation. To gain insight into the sex- and tissue-specific regulation of progesterone receptors, protein binding on a progesterone receptor-oestrogen response element and mRNA levels for progesterone receptor (PR)-A and PR-B were compared between female and male rats following oestradiol benzoate replacement treatment in hypothalamic and pituitary tissue. Both male and female pituitary protein extracts demonstrated an increase in nuclear protein binding activity to a progesterone receptor-oestrogen response element following oestradiol benzoate treatment. However, there was a greater difference in total binding activity seen in the female pituitary extracts compared to male pituitary protein extracts. In both cases, reflecting the binding data, oestradiol benzoate pretreatment led to an increase in pituitary PR-B messenger RNA, although this increase was significantly larger in females than in males. Oestradiol benzoate treatment also led to a significant increase in specific binding of hypothalamic nuclear proteins to the progesterone receptor oestrogen response element from both females and male hypothalamic extracts. In addition, PR-B messenger RNA was induced by oestradiol benzoate treatment in the female rat hypothalamus, under circumstances where no PR-A could be detected. The male also demonstrated an increase in PR-B messenger RNA following oestradiol benzoate treatment, with undetectable levels of PR-A, although to a lesser degree than that seen in the female. The predominance of PR-B over PR-A messenger RNA in rat hypothalamus and pituitary, and the quantitative differences between female and male rats, could both contribute to the greater responsiveness of female rats to progesterone with respect to control over luteinizing hormone release from the pituitary, and lordosis behaviour regulated by hypothalamic neurones.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.0007-1331.2001.00750.x
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Development and use of an ultra thin fiber-reinforced denture palate (2002)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of prosthodontics 11 (2002), S. 0 
    Details
    ISSN: 1532-849X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1532-849X.2002.328_35.x
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Associations of serum concentrations of IgG, IgA, IgM and interleukin-1β with early-onset periodontitis classification and race (2002)
    Oxford, UK : Munksgaard International Publishers
    Journal of clinical periodontology 29 (2002), S. 0 
    Details
    ISSN: 1600-051X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background: The significance of serum concentrations of various antibodies and cytokines in the pathogenesis of early-onset periodontitis (EOP) is not well understood. Recent reports suggest differences between young blacks and whites in certain humoral responses, regardless of periodontal status. This study was undertaken to compare the serum concentrations of IgG, IgA, IgM, and IL-1β in EOP subjects with that of healthy controls, and to study the effect of race on these levels.Material and Methods: This case-control study included 228 individuals, 19–25 years old who were selected from a larger population examined in the National Survey of Oral Health of United States Children in 1986/1987. The subjects were classified by their EOP status and they included 166 subjects with EOP and 62 healthy controls. Blood samples were used to assess the serum concentrations of IgG, IgM, IgA, IgG subclass, and IL-1β.Results: The serum concentrations of IgG, IgG subclasses, IgA, and IgM in blacks were not significantly different in the generalized, localized and incidental EOP groups as compared to the healthy controls. The serum IL-1β concentration was slightly and uniformly lower in the EOP groups than in the control group, although not statistically significant. Blacks had significantly higher serum concentrations of total IgG, and of IgG1, IgG2 and IgG3 than whites and Hispanics. Hispanics had significantly higher serum concentrations of IgM and IgG4 than whites and blacks. Hispanics also had a significantly higher serum concentration of IL-1β than blacks.Conclusions: Total antibody response in blacks is not associated with EOP classification. Race has a significant effect on serum antibody concentrations irrespective of disease classification, with blacks having significantly higher serum concentrations of IgG1, IgG2 and IgG3 than whites and Hispanics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1034/j.1600-051X.2002.290506.x
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  • 7
    Electronic Resource
    Electronic Resource
    IN MEMORY OF JAMES L. FRAMO: A PERSONAL NOTE 1922–2001 (2002)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of marital and family therapy 28 (2002), S. 0 
    Details
    ISSN: 1752-0606
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Psychology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1752-0606.2002.tb01164.x
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  • 8
    Electronic Resource
    Electronic Resource
    Extending product profiling through simulation (2002)
    Bingley : Emerald
    International journal of operations & production management 22 (2002), S. 956-971 
    Details
    ISSN: 0144-3577
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Economics
    Notes: Manufacturing strategy literature continues to be split between process and content. Content has continually evolved and more precise applications have been developed. Process has lagged behind because of the difficulty in conducting research in this area. Little has been developed since the introduction of the product profiling mechanism. This study presents a methodology that extends the product profiling technique, resulting in more appropriate content recommendations. Two case examples, one manufacturing operation and one service operation, are provided to demonstrate the improved performance of the product profile when combined with simulation. In both cases, problem symptoms caused the organization to seek help in scheduling operations. Cursory study clearly indicated that neither organization had a scheduling problem, but rather, an improper relationship between the marketing and operations functions of the organizations. In both cases, it was possible to demonstrate, with product profiling, the lack of coordination between the marketing and operating functions of the organizations. Product profiling alone, however, was not sufficient to convince either organization to implement proper solutions. When changes were supplemented with a graphical simulation analysis, both organizations agreed with the recommendations and began implementing change.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1108/01443570210446306
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