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  • 2000-2004  (2)
  • 1990-1994
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  • 2003  (2)
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  • 2000-2004  (2)
  • 1990-1994
  • 1980-1984
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  • 1
    ISSN: 1365-3059
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Patterns of variation were determined in anastomosis, pathotype and genotype of Colletotrichum lindemuthianum samples collected from individual plants of common bean cultivars from four locations in the Mexican highlands. In Chihuahua, 22 polymorphic AFLP bands in isolates taken from a single plant identified five distinct genotypes. In Michoacán, nine genotypes were identified based on a total of only six polymorphic bands. Combined cluster analysis of all isolates from individual plants grouped them geographically. In Chihuahua, in isolates from 16 individual plants, only nine genotypes were identified and all samples were found to belong to the same anastomosis group. However, analysis of selected isolates revealed two new pathotypes not reported previously from Chihuahua (races 449 and 467). In contrast, in Michoacán all 13 isolates from individual plants were found to have distinct genotypes, and in Mexico State only two pairs of isolates among 20 samples had identical genotypes. Although no pathotype variation was determined, five anastomosis groups were identified in Michoacán and three in Mexico State. These results suggest that patterns of variation in genotype and anastomosis groups are complex in the different locations sampled, and that no strong relationship exists between genotype, pathotype or anastomosis group.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1365-2559
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Aims:  The Goseki grouping of gastric adenocarcinoma has been suggested as a possible prognostic factor. In those centres where it is used, it may be valuable to assess the Goseki grouping of a tumour on the initial diagnostic biopsy as well as on the resection specimen since it may in theory influence management. We examined the robustness of Goseki grouping of gastric adenocarcinoma in representative sections from resection and biopsy specimens in order to assess the consistency of agreement among a group of pathologists.Methods:  A single representative block from 100 gastric resection specimens was studied using a haematoxylin and eosin and mucin (alcian blue/periodic acid–Schiff) stain. These were circulated in batches to members of a group of 12 pathologists who each completed a simple proforma confirming the presence of carcinoma and assigning a Goseki group. In a second circulation the diagnostic biopsy specimen taken prior to resection was examined in the same way. This allowed comparison of the Goseki group of the biopsy and resection specimens.Results:  In both studies κ statistics showed good agreement on tubular differentiation of the carcinoma, but only moderate agreement for the intracellular mucin production, resulting in moderate agreement for the final Goseki group. Correlation between the Goseki group assigned on the biopsy and resected specimens was seen in 62% of the cases. However, the reproducibility was low (κ 0.375).Conclusions:  The Goseki grouping of resected gastric adenocarcinoma is reproducible and can be used in prognostication. Goseki grouping of biopsy specimens is of limited value in predicting the Goseki group assigned to the resected carcinoma.
    Type of Medium: Electronic Resource
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