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  • 2000-2004  (7)
  • 1980-1984
  • 1970-1974
  • 2004  (7)
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  • 2000-2004  (7)
  • 1980-1984
  • 1970-1974
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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    International journal of cosmetic science 26 (2004), S. 0 
    ISSN: 1468-2494
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: It has been known that high amounts of ‘heat shock proteins (HSPs)’ are produced under heat and other environmental stresses in cells. Recently, it was reported that HSP could also be accumulated in some dermal cells to protect the cellular proteins from damage caused by ultraviolet radiation. Here, the authors have focused on thermophilic cyanobacteria and the heat shock treatment. Thermophilic cyanobacteria are known to thrive under extreme environmental conditions, and produce distinctively high amounts of HSP when exposed to higher temperatures. We tested cell extract from heat-shocked cyanobacterial cells on a number of skin-related biological activities and found it significantly effective. The cyanobacterial cells, originally collected from a spa as hot as 55 °C, were cultivated in the laboratory at 50 °C and broken by a freeze-fracture method. The extract thus obtained had a superoxide dismutase (SOD)-like activity and inhibited lipid peroxide formation. We found that the extract obtained from the heat-shocked (at 63 °C) cells showed a much stronger SOD-like activity, while the inhibitory effect on lipid peroxide formation remained almost the same. Furthermore, the SOD-like activity could withstand heat up to 70 °C for as long as 1 h. Most remarkably, supplementing this heat-shocked extract strongly promoted the proliferation of human dermal fibroblast culture. Extracts from the cells grown at a regular temperature (50 °C) did not promote the proliferation of the fibroblasts. The heat-shocked extract was fractionated by ultrafiltration for further analysis. A fraction (molecular weight: 10 000–30 000) has shown the strongest activity so far. These results indicate that the heat-shocked cyanobacterial extract with its increased amounts of HSPs is a promising potent ingredient for anti-aging cosmetic materials.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    Cytopathology 15 (2004), S. 0 
    ISSN: 1365-2303
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    Journal of fish diseases 27 (2004), S. 0 
    ISSN: 1365-2761
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: A histopathological study was carried out on ayu, Plecoglossus altivelis, with bacterial haemorrhagic ascites. The fish were obtained from culture ponds in Wakayama Prefecture in 2003. The causative agent was identified as Pseudomonas plecoglossicida by a slide agglutination test using anti-P. plecoglossicida FPC941 serum. Histopathological studies revealed lesions in spleen, kidney, liver, intestine, heart and gills. Lesions in the spleen and haematopoietic tissue were prominent and invaded by P. plecoglossicida. Necrotic lesions accompanied by haemorrhage, fibrin deposition and oedema occurred in the splenic pulp and sheathed tissue, and in the kidney. The liver also had necrotic lesions and abscess formations. However, the intestine, heart and gills were only slightly invaded by P. plecoglossicida. No lesions or bacteria were observed in the brain.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Munksgaard International Publishers
    Journal of clinical periodontology 31 (2004), S. 0 
    ISSN: 1600-051X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Objectives: Recently, interleukin (IL) 4 gene polymorphisms have been analyzed in association with periodontitis. Genetic differences between Caucasian and Japanese patients with periodontitis have previously been detected. The aim of the present study was to analyze IL-4 genotypes in Caucasian and Japanese patients with aggressive periodontitis (AgP).Material and Methods: One hundred and twenty-four subjects were included in the study, 31 Japanese and 30 Caucasian patients with generalized AgP, plus 30 Japanese and 33 Caucasian healthy controls. IL-4 polymorphisms were determined by polymerase chain reaction. A logistic regression was used to investigate the possible association of the genotypes with the disease in both populations. Odds ratio (OR) estimates were analyzed for allele frequencies.Results: No significant association of IL-4 polymorphisms with the risk of AgP was determined in either population. However, the allele frequencies showed different results between populations. The carriage of the polymorphism in intron 2 was higher in Caucasian patients compared with controls (OR: 2.0, 95% confidence interval: [1.0;4.2]. Furthermore, the frequency of the IL-4 promoter/intron 2 composite genotype (PP+/IP+) in patients and controls, respectively, was found to be approximately 25% and 60% higher in the Japanese population than in the Caucasian population.Conclusion: There was no evidence of an association of IL-4 genotypes and AgP in either population, although the frequencies of the IL-4 genotypes in the Japanese and the Caucasians were different.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1434-6036
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract. The feasibility of three-dimensional (3-D) photonic crystals made using textile technology was investigated. Three different textures consisting of the cotton-yarn and TiO2 dispersed resin; a crossed linear-yarn laminated fabric, a multi layered woven fabric, and a 3-D woven fabric, were fabricated. The microwave attenuation of the transmission amplitude through these photonic crystals was measured. The straight cotton-yarn as well as the wavy cotton-yarn/TiO2 dispersed resin photonic crystals exhibited band gaps in the 6 to 15 GHz range. Thus, we could fabricate successfully 3-D photonic crystals using textile technology.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 261-263 (Apr. 2004), p. 1313-1318 
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: A fatigue detecting sensor that enables easy and precise estimation of fatigue damage of machines and structures was developed, based on the crack growth characteristics of metal. The sensor is composed of a metal foil with a single edge notch and a base metal foil. The two metal foils are bonded at the both far ends.The sensor is attached with an adhesive to the surface of structural member which is subjected to cyclic loads. The fatigue damage of the member is detected as the fatigue crack initiation from the notch tip of the sensor. The fatigue crack growth rate is independent of the crack length. The metal foil of the sensor is given pre-tension, so the sensor has stable crack growth characteristics independent of the average strain. The crack growth length is measured in a certain period after the installation. The length is converted to the fatigue damage of the member during the samplingperiod of sensor installation. Since no measuring instrument and signal wiring is necessary, the diagnosis procedure becomes easy and the cost for structural health monitoring could be reduced.With such small size of the sensor as conventional strain gages, the pin-pointed application of the sensor to the hot spot of structural stress concentration, where is important for the fatigue strength estimation of welded structures, is possible. Therefore, precise fatigue remaining life assessment could be carried out. Sensors with several strain ranges were developed, so application to vast strain range is possible. Even such a small strain range as 1/10000 is able to be detected.The sensors have been applied to various products like steel bridges, rolling stocks, ships, etc
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    The European physical journal 35 (2004), S. 267-275 
    ISSN: 1434-6052
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract. We examine the soft supersymmetry breaking parameters in supersymmetric theories on a slice of AdS5 which generate the hierarchical Yukawa couplings by dynamically quasi-localizing the bulk matter fields in an extra dimension. Such models can be regarded as the AdS dual of the recently studied 4-dimensional models which contain a supersymmetric CFT to generate the hierarchical Yukawa couplings. In such models, if supersymmetry breaking is mediated by the bulk radion superfield and/or some brane chiral superfields, potentially dangerous flavor-violating soft parameters are suppressed with an appropriate correlation with the Yukawa coupling suppression, thereby avoiding the SUSY flavor problem in a natural manner. We present some models of radion-dominated supersymmetry breaking which yield a highly predictive form of soft parameters in this framework, and discuss the constraints from flavor-changing rare processes. Most of the discussions in this paper can be applied also to models with a flat extra dimension in which the Yukawa hierarchy is generated by quasi-localizing the bulk matter fields in the extra dimension.
    Type of Medium: Electronic Resource
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