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  • 2015-2019
  • 1975-1979  (5)
  • 1915-1919
  • Head twitches  (3)
  • intestinal anastomosis  (2)
  • 1
    Electronic Resource
    Electronic Resource
    The effect of cartilage-bone marrow extract (CBME) on the healing of intestinal anastomosis (1976)
    Springer
    Surgery today 6 (1976), S. 35-42 
    Details
    ISSN: 1436-2813
    Keywords: cartilage-bone marrow extract ; wound healing ; intestinal anastomosis ; hypoproteinemia ; reanastomosis ; long term administration of corticoid
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The intestinal anastomosis made under various conditions with and without treatment with cartilage-bone marrow extract were compared. The preoperative or postoperative administration of cartilage-bone marrow extract was found to increase mechanical strength of the intestinal anastomosis, even under unfavorable conditions such as hypoproteinemia, long term treatment of corticoid or reanastomosis. Formation of connective tissue and healing process were also found to be promoted by cartilage-bone marrow extract treatment.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02468618
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    An alternative one layer inverting suture technique for intestinal anastomosis (1979)
    Springer
    Surgery today 9 (1979), S. 322-326 
    Details
    ISSN: 1436-2813
    Keywords: one layer anastomosis ; intestinal anastomosis ; tensile strength ; bursting pressure ; mechanical strength
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract An alternative method of anastomosis using a suture one layer inverting was proposed, in which the sutures are placed the serosa, proper muscle layer, submucosal layer and muscularis mucosae, but not mucosa. An experimental study using canine intestine revealed that tensile strength as well as bursting pressure at the anastomotic site is significantly superior in our method to the end-on method.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02468632
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Effects of amitriptyline and isocarboxazid on 5-hydroxytryptophan induced head twitches in mice (1976)
    Springer
    Psychopharmacology 48 (1976), S. 101-104 
    Details
    ISSN: 1432-2072
    Keywords: Head twitches ; 5-Hydroxytryptophan ; Serotonin ; 5-Hydroxyindolacetic acid ; Amitriptyline ; Isocarboxazid ; Probenecid
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Effects of amitriptyline and isocarboxazid on brain 5-HT and 5-HIAA were examined in relation to their action on 5-HTP induced head twitches. Amitriptyline reduced 5-HTP induced head twitches but isocarboxazid increased them. Both amitriptyline and isocarboxazid caused a significant increase of brain 5-HT concentration in 5-HTP treated mice. Amitriptyline also caused a significant increase of 5-HIAA concentration, while isocarboxazid reduced 5-HIAA concentration in the brains of 5-HTP treated mice. Probenecid, which significantly increased 5-HIAA concentration without affecting brain 5-HT concentration in 5-HTP treated mice, reduced 5-HTP induced head twitches. These results suggest that 5-HTP induced head twitches might be induced by an increase of 5-HT concentration, and reduced by an increase of 5-HIAA or a decrease of 5-HT concentration in the brains of mice.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00423314
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    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Head twitches induced by benzodiazepines and the role of biogenic amines (1976)
    Springer
    Psychopharmacology 49 (1976), S. 259-261 
    Details
    ISSN: 1432-2072
    Keywords: Head twitches ; Benzodiazepines ; Serotonin ; Dopamine ; Norepinephrine ; GABA ; Glycine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Clonazepam, one of the benzodiazepines, induced head twitches in mice in a dose-dependent manner and sustained them for at least 120 min. Some of the benzodiazepines such as nitrazepam, fludiazepam, and nimetazepam also significantly induced head twitches at doses higher than 10 mg/kg, but other benzodiazepines like diazepam, flurazepam, oxazepam, medazepam, and chlordiazepoxide did not significantly induce head twitches at doses up to 60 mg/kg. The head twitches induced by clonazepam were more strongly blocked by an antiserotonin drug, cyproheptadine than catecholamine receptor blocking drugs, haloperidol, propranolol, and phentolamine, and were not blocked by GABA receptor blocking drugs, bicuculline and picrotoxin, as well as by a glycine receptor blocking drug, strychnine. Clonazepam also increased the head twitches induced by mescaline, a serotonin receptor stimulant. These results indicate that the head twitches induced by clonazepam might be mediated via serotonergic neuron systems.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00426826
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    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Effect of benzodiazepines on central serotonergic neuron systems (1977)
    Springer
    Psychopharmacology 53 (1977), S. 121-126 
    Details
    ISSN: 1432-2072
    Keywords: Benzodiazepines ; Serotonin ; Mescaline ; Head twitches ; Muscle relaxation ; Anticonvulsion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Intracerebral (i.c.) injection of serotonin (5-HT) into mice induced head twitches in a dose-dependent manner at 10 min after injection. The head twitches induced by 5-HT (i.c.) were potentiated by the pretreatment of isocarboxazid (3 mg/kg i.p.), and inhibited by cyproheptadine (0.3 mg/kg i.p.), a 5-HT antagonist. Benzodiazepines such as fludiazepam and diazepam potentiated the head twitches induced by 5-HT (i.c.) in a dose-dependent manner. Mescaline (50 mg/kg i.p.) also induced head twitches in mice at 15 and 30 min after injection. Benzodiazepines potentiated the head twitches induced by mescaline in a dose-dependent manner. Cyproheptadine blocked the potentiating effect of benzodiazepines on the head twitches induced by both 5-HT (i.c.) and mescaline. By repeated administration of fludiazepam or diazepam for 5 days, the potentiating effect of both drugs on the head twitches induced by mescaline was unchanged and their anticonvulsant effects were not modified. In contrast, the potency of both drugs on muscle relaxation was significantly decreased by repeated administration. Benzodiazepines failed to change the uptake of 5-HT into the synaptosomal fractions from the rat brain. These results suggest that the pharmacological action of benzodiazepines is derived at least in part from their activating effect on 5-HT receptors.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00426480
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    Paper (German National Licenses)
    Fulltext
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