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  • 2005-2009  (2)
  • 2000-2004  (2)
  • 1935-1939  (2)
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  • 1
    Electronic Resource
    Electronic Resource
    Risk factors for oral soft tissue lesions in an adult Spanish population (2002)
    Oxford, UK : Munksgaard International Publishers
    Community dentistry and oral epidemiology 30 (2002), S. 0 
    Details
    ISSN: 1600-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract –Objectives: The aims of this study were (i) to determine the prevalence of oral lesions in adults over 30 years old in the city of Oviedo (Spain), and (ii) to analyze the relationship between the prevalence of oral lesions, toxic habits (tobacco and alcohol) and denture wearers in these patients.Methods: A representative sample of the adult population in Oviedo (Spain) was obtained through randomized sampling (n = 753); a total of 308 (41%) subjects were finally included in the study. The observed oral pathology was classified according to the WHO criteria and earlier epidemiological studies.Results: A little over half of all patients (51.1%) had oral lesions. The most frequent lesions were frictional lesion (7.5%), traumatic ulcer (7.1%), denture stomatitis and pseudomembranous candidosis (6.5%), followed by melanin pigmentation (5.8%) and denture-induced hyperplasia (5.2%), plicated tongue (3.9%), lichen planus and hemangioma (3.2%), angular cheilitis and cheek biting (2.9%), fibrous hyperplasia and coated tongue (2.6%), recurrent aphthae (1.9%) and oral leukoplakia (1.6%). In relation to leukoplakia, the odds ratio (OR) of heavy drinkers was 15.98 and the OR of heavy smokers was 12.37. The OR of heavy smokers or heavy drinkers diagnosed of frictional lesion was four times greater than that of nonsmokers or nondrinkers. The OR of heavy smokers with melanic pigmentations was 4.08. The OR of complete denture wearers with candidosis was 11.38. The OR of partial removable denture wearers with hemangioma was 5.01.Conclusions: This study shows the relation of heavy tobacco and heavy alcohol to traumatic keratosis and leukoplakia, and of complete dentures to pseudomembranous candidosis, fibrous hyperplasia and stomatitis. Programs designed to eradicate toxic factors (alcohol and tobacco) should, therefore, be implemented with adequate maintenance of dentures.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1034/j.1600-0528.2002.00048.x
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  • 2
    Electronic Resource
    Electronic Resource
    Clinicopathological and immunohistochemical analysis of 20 cases of Merkel cell carcinoma in search of prognostic markers (2005)
    Oxford, UK : Blackwell Science Ltd
    Histopathology 46 (2005), S. 0 
    Details
    ISSN: 1365-2559
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Aims:  To evaluate the clinicopathological and immunohistochemical characteristics of Merkel cell carcinoma (MCC) in an attempt to find new, potentially significant, prognostic markers.Methods and results:  Clinical data and follow-up, histopathological features (pattern, cell size, thickness, mitoses, vascular invasion, lymphocytic infiltration) and immunohistochemical detection [CK20, thyroid transcription factor (TTF-1), chromogranin A, synaptophysin, p53, Ki67, Fli-1, CD99, c-Kit] were evaluated in 20 cases of MCC. Fli-1 and CD99 were detected in 90% and 55% of cases, respectively. Tumour size 〉 30 mm, stage II, ‘absent’ lymphocytic infiltration, and the presence of 〉 50% of Ki67+ tumour cells, were found to be prognostic indicators of disease-free interval (DFI), but only ‘absent’ lymphocytic infiltration constituted an independent prognostic factor of DFI after multivariate analysis. For overall survival, the same variables, together with local recurrence and lymph node involvement, had prognostic significance, with only local recurrence as an independent prognostic factor after multivariate analysis.Conclusions:  Absence of lymphocytic infiltration and Ki67 immunoreactivity in more than 50% of tumour cells should be evaluated in conjunction with other well-known prognostic markers in MCC. Furthermore, recognizing that Fli-1 and CD99 expression is commonly found in MCC by immunohistochemistry may avoid misinterpretation in the differential diagnosis of MCC with other small round cell tumours.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2559.2005.02158.x
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  • 3
    Electronic Resource
    Electronic Resource
    Dynamics of directional selectivity in MT receptive field centre and surround (2005)
    Oxford, UK : Blackwell Science Ltd
    European journal of neuroscience 22 (2005), S. 0 
    Details
    ISSN: 1460-9568
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: We studied receptive field organization of motion-sensitive neurons in macaque middle temporal cortical area (MT), by mapping direction selectivity in space and in time. Stimuli consisted of pseudorandom sequences of single motion steps presented simultaneously at many different receptive field locations. Spatio-temporal receptive field profiles were constructed by cross-correlating stimuli and spikes. The resulting spike-triggered averages revealed centre-surround organization. The temporal dynamics of the receptive fields were generally biphasic with increased probability for the preferred direction at short latency (50–70 ms) and decreased probability at longer latency (80–100 ms). The response latency of the receptive field surround was on average 16 ms longer than that of the centre. Our results show that surround input and biphasic behaviour reflect two different mechanisms, which make MT cells specifically sensitive to motion contrast in space and time.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1460-9568.2005.04363.x
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  • 4
    Electronic Resource
    Electronic Resource
    Spit-platform temperate carbonates: the origin of landward-downlapping beds along a basin margin (Lower Pliocene, Carboneras Basin, SE Spain) (2003)
    Oxford, UK : Blackwell Science Ltd
    Sedimentology 50 (2003), S. 0 
    Details
    ISSN: 1365-3091
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Geosciences
    Notes: Lower Pliocene temperate carbonates exhibit landward-downlapping beds at the southern margin of the Carboneras Basin in south-eastern Spain. This rarely documented stratal geometry resulted from the accumulation of bedded bioclastic carbonate sand and gravel by longshore currents along a spit platform located a few hundred metres from the palaeoshoreline. The top of the spit platform was covered by shoals that extended over a gently dipping ramp inclined to the north. On the landward slope of the spit, sediments washed over from the shoal area were deposited in parallel-laminated beds with a southward dip of 8–11°. These beds aggraded and retrograded after an increase in accommodation space, probably related to an Early Pliocene eustatic sea-level rise. As a result, the beds downlap onto the underlying unconformity surface in a shoreward direction. Eventually, the depression between the shoreline and the spit platform was filled, and a gentle ramp became established. These Pliocene exposures in the Carboneras Basin and a similar Upper Miocene example in southern Spain suggest that landward-downlapping stratal geometries can be expected in nearshore temperate carbonates along basin margins, and demonstrate a similarity in sedimentary dynamics to siliciclastic sands and gravels.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-3091.2003.00564.x
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  • 5
    Electronic Resource
    Electronic Resource
    Valerius Flaccus—Poet of Romance (1938)
    Cambridge : Cambridge University Press
    Greece and Rome 7 (1938), S. 137-148 
    Details
    ISSN: 0017-3835
    Source: Cambridge Journals Digital Archives
    Topics: Archaeology , Classical Studies
    Notes: The period of the Flavian emperors (A.D. 69–96) was distinguished by a notable revival of epic poetry. No fewer than three poets, whose work is extant, flourished contemporaneously—Statius, Valerius, and Silius. It was indeed an age of literary figures, including Martial, Pliny the Younger, Quin-tilian, and Tacitus. Statius and Valerius are interesting as epic poets in that they broke away from the tradition of national and patriotic poetry prescribed for their art from the time of Ennius. Silius, on the other hand, remained true to the convention of Latin epic, and, in an age when the stimulus of national pride was losing its effect on poetry, produced a long poem that lacked originality and inspiration.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1017/S0017383500005568
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  • 6
    Electronic Resource
    Electronic Resource
    Persius—Poet of the Stoics (1939)
    Cambridge : Cambridge University Press
    Greece and Rome 8 (1939), S. 172-182 
    Details
    ISSN: 0017-3835
    Source: Cambridge Journals Digital Archives
    Topics: Archaeology , Classical Studies
    Notes: There can be little doubt that the extant remains of Persius form the whole of his writings. In his boyhood he had indulged in the literary exercises of the classroom, and these immature efforts included a tragedy, a book of travels, and some lines on the elder Arria, whose Non dolet1 was an appropriate subject for a young Stoic to commemorate. These experiments had little merit, otherwise they would not have been destroyed on the advice of Cornutus, his friend and teacher and literary executor.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1017/S0017383500006380
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